Gene Information

Name : hemC (A1C_03825)
Accession : YP_001493548.1
Strain : Rickettsia akari Hartford
Genome accession: NC_009881
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 684699 - 685604 bp
Length : 906 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGATAAATTCTATCAGAATAGGTACAAGAAACAGTCCACTTGCTTTAATACAAACTAATTTAGTGATTCAGCAAATCAA
ACAATTTTTTCCTGATATTAATTGTGCAATAGTACCTATTATTACTAGCGGTGATTTAATCCAAAATAAACCATTATACG
ATATAGGAGGTAAAGCTTTATTTTTAAAGGAAATAGAGCAAGCCTTGCTTGATAAAAAAATTGACTTAGCCGTTCATTCT
TTGAAAGACGTACCGGGTAGAATACCTGAAGAGCTAGTAATTTCCGCTGTTTTAGAGCGTGAAGACCCAAGAGATGTTTT
TGTATGTTTAAATTATAAATCCATAAAAGAACTGCCGCAACATTCCGTAATAGGTAGCTCGGCAGTCCGAAGAAAAGCAT
TTATCCAAAAAATAAGACCAGATTTAAAGGTAACAATTTTTAGAGGGAATGTTGATTCAAGAATAAAAAAGCTAATGACC
GGCGAAGTTGATGCAACAATTTTAGCATATGCGGGTCTGAAAAGGCTTGGAGCGTTTAATCCAGAATATTGTCATTTGAT
AGAATATTCGCATATGTTGCCGTGTGTAGGGCAGGGAGTCATTGCAGTTGAGATACGACAAAATGATAATTCTATGCTTG
AGATATGTAACCAAATTAATCATCTGCCTACCTGTGAACTAATAAAACCCGAAAGAGCGTTTTTAGAATATCTAGATGCT
AATTGCCGTACACCGATTGGTACTTACTCACAATATCTAGATGCGGATAATATACAAACCGATTTTATGCTTGGTAACCC
CGATTGCAGTAAAATAACCTTCCACACTGAAATTACCAATATCAAAACTTCAAAAGAAGGTGGCATCAAAGCCGCTAAAA
TGATGTTGAATCAACTGAAAAAATGA

Protein sequence :
MINSIRIGTRNSPLALIQTNLVIQQIKQFFPDINCAIVPIITSGDLIQNKPLYDIGGKALFLKEIEQALLDKKIDLAVHS
LKDVPGRIPEELVISAVLEREDPRDVFVCLNYKSIKELPQHSVIGSSAVRRKAFIQKIRPDLKVTIFRGNVDSRIKKLMT
GEVDATILAYAGLKRLGAFNPEYCHLIEYSHMLPCVGQGVIAVEIRQNDNSMLEICNQINHLPTCELIKPERAFLEYLDA
NCRTPIGTYSQYLDADNIQTDFMLGNPDCSKITFHTEITNIKTSKEGGIKAAKMMLNQLKK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 1e-47 41
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 1e-47 41