Gene Information

Name : smpB (A1C_03205)
Accession : YP_001493435.1
Strain : Rickettsia akari Hartford
Genome accession: NC_009881
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 584005 - 584463 bp
Length : 459 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGACCGAATATAAGAAAGTTATTGCACAAAATAATAAAGCCATTTTTAATTATTTTATTGAAGAAAGATTAGAAGCAGG
TATTGTATTAAATGGGAGTGAAGTACAGTCTCTGCGTCAAGGCAAAGCTTCTATAGAGGAAAGCCATGCGGCAGATACCG
GACATGAGGTATTTTTGTATAACTGCCATATTGCAGAATATGAAAAAGCGAATAGATTTAATCATTCTACTCGTAGACCT
CGTAAATTATTGTTGCATACTAAAGAGATAAAGAAAATTATCGGTAGAATTAGAATAAAAGGCTATACGCTAGTAGCTCT
TTCTATGTATTTTAATAAACAAAATAAAGTGAAAGTTGAGCTTGGTATTGCTAAAGGTAAGAAATTACATGATAAAAGAG
AATCAATTAAAGAAAAAGACTGGAAAAGAGATCAGAGTAGATTAATAAGGCAGAAATAA

Protein sequence :
MTEYKKVIAQNNKAIFNYFIEERLEAGIVLNGSEVQSLRQGKASIEESHAADTGHEVFLYNCHIAEYEKANRFNHSTRRP
RKLLLHTKEIKKIIGRIRIKGYTLVALSMYFNKQNKVKVELGIAKGKKLHDKRESIKEKDWKRDQSRLIRQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 1e-23 48
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 8e-20 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-18 46