Gene Information

Name : A1C_06075 (A1C_06075)
Accession : YP_001493956.1
Strain : Rickettsia akari Hartford
Genome accession: NC_009881
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1085018 - 1086295 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAGTATCAAATGGATTAGAGAAAATCAAGAATTATTCGATGAAAAGCTTAGCAAAAGATTTATTGAACCTATGTC
TAGTAAAATTGCTATGCTCGACGGAGAGAAAAGAAAAATTACGAGTTTAATTCAAGAATTTCAGCATGCACGTAAGGTAA
AATCAAAGATTTTAGGTAATATGGCTTCTAAAAGCGGCGAAGAGTTTGAAGCGATACAAAGAGATGTCAAACATATAAAT
GAGAAGTTGGAAGAACTTGAACAGGATCTAAATAATAATAACGAATTAAATGAACTATTAAATATGCTTCCTAATATTCC
GGACGAAGAAGTACCTTACGGAATGGATGAAAGTATGAATAAATTAGTTCGTACTTACGGAGAGACAAATCCAAATGCTT
TAAATAAACAGCATTTTGAACTAGGTACAAAATTAAATTTAATGGATTTTGAACAAACTGCTAAAATTTCTGGAGCTAGA
TTTGTAACGTTAAAAGGTGATTTAGCAAAGTTAGAACGTGCTTTAATTAATTTTATGATTGATGTTCATACTAAAGAGTT
TAACTTCTTTGAGATGTCACCTCCAGTATTAGTTCGAGATAATGCTATGTATAATTCAGGACAACTACCTAAATTTGCTG
AAGAGTCTTTTGCAACAACAAATGGTTACAGACTAATTCCAACCGCAGAAGTATTTTTAGTAAATATAGTCGCCGATACT
ATAATACCAAGGGAAAAATTGCCGATGCGTTATGTTGCTTACACCCCGTGCTTTAGATCAGAAGCAGGTAGTAGCGGTAG
AGATACAAGAGGTATGATCAGATTACATCAGTTCGGTAAAGTTGAGCTAGTATCTATTACTACCCCGGAAGAATCAAAAC
ATGAGCATGAATATATAACTAATTCATCAGAGACTATTTTACAAAAACTGAATCTTCCTTATCGTGTTATGTTACTTTGC
ACCGGAGATATGGGATTTGCGGCAAAAAAAACCTATGATATAGAGGTGTGGCTTCCGGGACAAAAGCAATATCGTGAAAT
TGCTAGCTGTTCTAATTGTGGAGATTTTCAAGCACGTAGAATGAAAGCAAGATATAAGGAATTCGGCAGTAACGAAACTA
CCTTAGTCCATACTTTAAATGCTTCAGGATTACCTATCGGAAGAACTATGGTTGCAATACTTGAAAATTATCAGAATGAA
GATGGCTCAATAACTATACCTGATGTCTTGATAAATTACATGGGAGGGTTACAAAAAATCACTACACATGGTGAATAA

Protein sequence :
MLSIKWIRENQELFDEKLSKRFIEPMSSKIAMLDGEKRKITSLIQEFQHARKVKSKILGNMASKSGEEFEAIQRDVKHIN
EKLEELEQDLNNNNELNELLNMLPNIPDEEVPYGMDESMNKLVRTYGETNPNALNKQHFELGTKLNLMDFEQTAKISGAR
FVTLKGDLAKLERALINFMIDVHTKEFNFFEMSPPVLVRDNAMYNSGQLPKFAEESFATTNGYRLIPTAEVFLVNIVADT
IIPREKLPMRYVAYTPCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESKHEHEYITNSSETILQKLNLPYRVMLLC
TGDMGFAAKKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNETTLVHTLNASGLPIGRTMVAILENYQNE
DGSITIPDVLINYMGGLQKITTHGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-78 46