Gene Information

Name : A1E_05000 (A1E_05000)
Accession : YP_001492701.1
Strain : Rickettsia canadensis McKiel
Genome accession: NC_009879
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : -
Position : 1019334 - 1020611 bp
Length : 1278 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAAATATCAAATGGATTAGAGAAAACCAAGAATTGTTTGATGAAAAGCTTAGCCAAAGATTTATTGAACCTATGTC
TAGTAAAATCGCTATGCTCGACGAAGAGAAAAGAAAAATTACGAGTTTAATTCAAGAATTTCAGCATGCACGTAGGGTGA
AATCGAAGATTTTAGGTAATATGACCTCTAAAAGCAGTGAAGAGTTTGAAGGTTTACAAAGAGATGTCAAACATATAAAT
GAGAAGTTGGAAGAACTTGAAAAGGATCTAAATAACAATAACGAATTAAATGAGCTATTAAATATGCTTCCTAATATTCC
GGACGACGAAGTACCTTACGGAATTGATGAAAGTATGAATAAATTAGTTCGTACTTACGGAGAGATAAATCCAAATGCTT
TAAATAAGCAGCATTTTGAACTAGGCACAAAATTAAATTTAATGGATTTTGAACAAACTACTAAAATTTCAGGAGCTAGA
TTTGTAACATTAAAAGGCGATTTAGCAAAGCTAGAACGTGCTTTAATTAACTTTATGATTGATGTTCATACTAAAGAGTT
TGACTTCTTTGAGATATCACCTCCAGTATTAGTTCGAGATAATGCTATGTATAATGCAGGACAACTACCTAAATTTACTG
AAGAGTCTTTTGCAACAACAAAGGGTTACAGACTAATTCCAACCGCAGAAGTATCTTTAGTCAATATAGTCGCTGATACT
ATTATATCAAGAGAAAAATTACCTATGCGTTACGTTGCTTACACCCAGTGCTTTAGATCAGAAGCAGGTAGTAGCGGTAG
AGATACAAGAGGTATGATTAGATTACATCAATTCGGTAAAGTAGAGCTTGTATCTATTACTACTCCAGAAGAGTCACAAA
ATGAACATGAATATATAACTAATGCATCAGAGACTATTTTACAAAAACTTAATCTACCTTATCGTATTATGTTACTTTGC
ACTGGAGATATGGGATTTGCAGCAAAAAAAACCTATGATATAGAAGTATGGCTTCCGGGACAAAAGCAATATCGTGAAAT
TGCGAGCTGTTCTAATTGTGGAGATTTTCAAGCACGTAGAATGAAAGCAAGATATAAAGAATTCGGCAGTAACGATACTA
CCTTAGTTCATACTTTAAATGCTTCAGGATTACCTATCGGAAGAACTATGGTTGCAATATTAGAAAGTTATCAGAACGAA
GATGGATCAATAACTATACCTGATGTCTTGATAAATTACATGGGAGGGTTACAAAAAATCACTACATATAGTGAATAA

Protein sequence :
MLNIKWIRENQELFDEKLSQRFIEPMSSKIAMLDEEKRKITSLIQEFQHARRVKSKILGNMTSKSSEEFEGLQRDVKHIN
EKLEELEKDLNNNNELNELLNMLPNIPDDEVPYGIDESMNKLVRTYGEINPNALNKQHFELGTKLNLMDFEQTTKISGAR
FVTLKGDLAKLERALINFMIDVHTKEFDFFEISPPVLVRDNAMYNAGQLPKFTEESFATTKGYRLIPTAEVSLVNIVADT
IISREKLPMRYVAYTQCFRSEAGSSGRDTRGMIRLHQFGKVELVSITTPEESQNEHEYITNASETILQKLNLPYRIMLLC
TGDMGFAAKKTYDIEVWLPGQKQYREIASCSNCGDFQARRMKARYKEFGSNDTTLVHTLNASGLPIGRTMVAILESYQNE
DGSITIPDVLINYMGGLQKITTYSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 5e-79 46