Gene Information

Name : guaA (Abu_0921)
Accession : YP_001489850.1
Strain : Arcobacter butzleri RM4018
Genome accession: NC_009850
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 916582 - 918117 bp
Length : 1536 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAACATGTACCAATAGTAGTTTTAGATTTCGGTAGTCAATATACTCAAATCATTGCTAGAAAACTTAGAGAAGCAGG
TGTTTACTCTGAAATAGTTCCTTATAATGAACCTATTGGAGATATAGTAGCTAGAACTCCAAAAGGAATTATTCTATCAG
GTGGACCAGCATCTGTTTATGCTGTTGATGCTTATCATCCAGATACTACAATATTTGAATTGGGTCTTCCAATTTTAGGT
ATTTGTTATGGAATGCAACTAATCTCTCAACATTTTGGTGGAAGTGTAATTCCAGCAAGTCATCACGAATATGGAAAAGC
TAAATTACAATTTGAAGTTGAAAATCCAATTTTCAAAGATACACAAGATGGTCAAATTGTTTGGATGAGCCACGGAGATA
GAGTTGAAAATATCCCTGCTGGATTTGAAAAAATCGCAACAAGTGAAAATTCTCCATTTGCAGCTATTGCAGATATAAAT
AGAAATATTTATGCATTTCAATTTCACCCAGAAGTTTATCACTCACAAGAAGGAAGCAAACTTCTTAAAAACTTTGCTAA
ACATATTTGTGGTTGTGAATCTACTTGGAATATGGGAAGTTTTGCAAAAGAGCAAATAAAACAAATCCAAGATAAAGTTG
GAAATAAAAAAGTATTATGTGCAGTTTCAGGTGGAGTTGATAGCTCAGTTGTAGCAACTTTATTAGCTGAAGCTATTGGA
GAACAAGTAATTCCTGTATTTGTAGATAATGGACTTTTAAGAGCAAATGAAAGAGAACAAGTTGAAACTATGTTCAAAAG
CAGAGGTGTAAATCTAATCACAGTTGATGCAAGTGAAACTTTCTTATCAAAACTAGCTGGTGTTACAGACCCAGAGAAAA
AAAGAAAAATCATTGGTGAAACATTTATCGAAGTATTTGATGTAGAAGCAAAAAAACACTCTGGAATTGAGTTTTTAGCA
CAAGGAACTTTATATACAGATGTTATCGAATCAGTTTCTGTAAAAGGTCCAAGTAAAACTATCAAATCTCACCATAATGT
TGGTGGTCTTCCTGATTGGATGAAATTTGAACTAATTGAACCTCTAAGAGAAATCTTCAAAGATGAAGTTAGAGCTTTAG
GATTAGAACTTGGTCTTCCAAAAAGTATGATAAGCAGACATCCATTCCCTGGTCCTGGTCTTGCTATTAGAATTATGGGT
GAAGTAAATAAACCTGATTTAGAACTTTTAAGAAAAGCTGATGTTATCATGCTTGATGTATTACATTCAACTGGATATTA
TGATAAAACTTGGCAAGCATTTACAGTATTATTAAATGTAAAATCTGTTGGTGTTATGGGTGATAATAGAACTTATGATA
ATACAGTTTGTGTAAGAATAGTAGATGCAACAGATGGTATGACAGCAACTTTTGCACATATTCCACATGAAATACTTGAA
ACTATCTCAAGAAGAATCATCAACGAAGTTGATGGAATCAACAGAGTAGTGTATGATATTTCATCAAAACCACCAGCAAC
TATCGAGTGGGAATAA

Protein sequence :
MKHVPIVVLDFGSQYTQIIARKLREAGVYSEIVPYNEPIGDIVARTPKGIILSGGPASVYAVDAYHPDTTIFELGLPILG
ICYGMQLISQHFGGSVIPASHHEYGKAKLQFEVENPIFKDTQDGQIVWMSHGDRVENIPAGFEKIATSENSPFAAIADIN
RNIYAFQFHPEVYHSQEGSKLLKNFAKHICGCESTWNMGSFAKEQIKQIQDKVGNKKVLCAVSGGVDSSVVATLLAEAIG
EQVIPVFVDNGLLRANEREQVETMFKSRGVNLITVDASETFLSKLAGVTDPEKKRKIIGETFIEVFDVEAKKHSGIEFLA
QGTLYTDVIESVSVKGPSKTIKSHHNVGGLPDWMKFELIEPLREIFKDEVRALGLELGLPKSMISRHPFPGPGLAIRIMG
EVNKPDLELLRKADVIMLDVLHSTGYYDKTWQAFTVLLNVKSVGVMGDNRTYDNTVCVRIVDATDGMTATFAHIPHEILE
TISRRIINEVDGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-134 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-134 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 2e-134 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-116 50