Gene Information

Name : clpC (BPUM_0071)
Accession : YP_001485331.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Virulence
Product : class III stress response-related ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 78323 - 80758 bp
Length : 2436 bp
Strand : +
Note : negative regulator of genetic competence MecB

DNA sequence :
ATGATGTTTGGAAGATTCACTGAAAGAGCTCAAAAGGTATTAGCACTTGCACAAGAAGAAGCCATTCGCCTAGGCCATAA
GAACATTGGTACTGAACACATTTTACTTGGTCTAGTACGTGAGGGTGAGGGCATCGCCGCAAAAGCGTTAGAAGCACTGG
GCCTTGTTTCAGATAAAATCCAAAAAGAAGTCGAAAGCTTGATTGGAAGAGGGCAAGAGGTGTCTCAAGCTATTCCTCAT
TATACGCCTAGAGCGAAGAAGGTCACTGAGCTTTCAATGGATGAAGCAAGAAAGCTCGGTCATTCCTATGTAGGGACAGA
ACATATTCTCTTAGGTCTTATTCGCGAGGGAGAGGGTGTAGCAGCCCGCGTTTTAAATAACCTCGGTGTGAGCTTAAATA
AAGCACGTCAGCAAGTCCTGCAGCTGCTTGGCAGTAATGAAACAGGTGCATCTGCCGCTGGCTCTAACAGCAATGCAAAT
ACCCCAACATTAGATAGCTTAGCAAGAGATTTAACAGCGATTGCGAAAGAAGACAGCTTGGACCCTGTCATTGGACGAAG
CAAAGAAATTCAGCGTGTCATTGAGGTCCTAAGCAGAAGAACAAAAAACAACCCGGTGCTGATTGGTGAGCCTGGTGTTG
GTAAAACAGCCATCGCTGAAGGTCTTGCACAGCAAATTATTCATAATGAAGTGCCTGAAATTCTACGCGATAAACGAGTG
ATGACGCTTGATATGGGAACCGTTGTAGCGGGAACAAAATATCGTGGTGAATTTGAGGATCGTTTGAAAAAAGTCATGGA
CGAAATTCGCCAGGCAGGAAATATCATTCTCTTCATTGATGAGCTTCATACACTGATTGGTGCTGGTGGAGCAGAGGGTG
CGATTGACGCATCTAATATTCTAAAACCATCCTTAGCACGTGGAGAGCTTCAATGTATCGGGGCGACAACATTAGATGAG
TACCGTAAATATATTGAAAAGGATGCTGCGCTTGAACGACGTTTCCAGCCAATTCAAGTAGATCAGCCATCAGTTGATGA
GAGTATTCAAATCTTAAGAGGACTTAGAGATCGTTATGAGGCACATCACCGTGTGTCCATTACAGATGAAGCGATTGAGG
CGGCAGTGAAGCTGTCTGACCGTTATATTTCTGATCGTTTCCTTCCAGATAAGGCGATTGATTTAATTGATGAGGCAGGT
TCGAAAGTCCGCTTACGTTCTTTCACAACACCGCCTAACCTAAAAGAACTAGAGCAAAAGCTGGATGAAGTACGCAAGGA
AAAAGATGCGGCTGTTCAAAGTCAGGAATTTGAAAAAGCAGCTTCTCTTCGCGATACAGAGCAGCGTCTGCGTGAAAAGG
TAGAGGTCACAAAGAAATCTTGGAAAGAAAAGCAAGGACAGGAGAATTCAGAGGTATCAGTGGATGATATCGCAATGGTT
GTCTCTAGCTGGACGGGAGTGCCTGTTTCAAAAATTGCCCAAACCGAAACAGATAAGCTTCTAAATATGGAACAATTACT
CCATTCTCGTGTAATTGGGCAGGATGAAGCAGTTGTCGCTGTAGCAAAAGCTGTGAGACGTGCGCGTGCTGGACTAAAAG
ATCCAAAACGTCCAATTGGCTCATTTATCTTCTTAGGCCCAACAGGGGTTGGTAAAACGGAGCTTGCAAGAGCACTCGCA
GAGTCTATTTTCGGTGATGAAGAAGCGATGATCCGTATTGATATGTCAGAATACATGGAGAAACACTCTACATCTAGACT
TGTTGGGTCACCTCCTGGCTATGTTGGCTATGAAGAAGGCGGACAACTGACTGAAAAAGTGAGAAGAAAACCTTATTCTG
TTGTGCTTTTAGACGAGATTGAAAAGGCGCATCCAGATGTATTCAACATCTTACTTCAAGTATTAGAAGATGGTCGTCTG
ACTGATTCTAAAGGGCGTACTGTTGACTTTAGAAATACGATTTTGATCATGACATCCAACGTTGGAGCTAGTGAACTGAA
GCGAAATAAATATGTTGGCTTTAACGTGCAGGATGAAGGTCAAAATTACAAGGATATGAAAGGCAAAGTGATGGGCGAGT
TGAAACGTGCGTTCAGACCAGAATTCATCAACCGTATTGATGAAATCATTGTCTTCCATTCACTTGAAAAGAAACATCTA
AAAGAGATTGTGTCTCTCATGTCTGATCAATTGACGAAACGATTAAAAGAACAAGACCTTTCAATTGAATTGACAGAAGC
AGCAAAAGCGAAGATTGCTGATGAAGGTGTAGACCTTGAGTACGGTGCGCGTCCGTTAAGAAGAGCGATTCAAAAGCATG
TGGAGGATCGACTTTCTGAGGAGCTTCTGAAGGGTAATATTGAAAAAGGTCAACAAATTGTATTAGATGTGGAAGATGGA
GAAATTGTCGTAAAAACGACGGCTGCTACGAACTAA

Protein sequence :
MMFGRFTERAQKVLALAQEEAIRLGHKNIGTEHILLGLVREGEGIAAKALEALGLVSDKIQKEVESLIGRGQEVSQAIPH
YTPRAKKVTELSMDEARKLGHSYVGTEHILLGLIREGEGVAARVLNNLGVSLNKARQQVLQLLGSNETGASAAGSNSNAN
TPTLDSLARDLTAIAKEDSLDPVIGRSKEIQRVIEVLSRRTKNNPVLIGEPGVGKTAIAEGLAQQIIHNEVPEILRDKRV
MTLDMGTVVAGTKYRGEFEDRLKKVMDEIRQAGNIILFIDELHTLIGAGGAEGAIDASNILKPSLARGELQCIGATTLDE
YRKYIEKDAALERRFQPIQVDQPSVDESIQILRGLRDRYEAHHRVSITDEAIEAAVKLSDRYISDRFLPDKAIDLIDEAG
SKVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREKVEVTKKSWKEKQGQENSEVSVDDIAMV
VSSWTGVPVSKIAQTETDKLLNMEQLLHSRVIGQDEAVVAVAKAVRRARAGLKDPKRPIGSFIFLGPTGVGKTELARALA
ESIFGDEEAMIRIDMSEYMEKHSTSRLVGSPPGYVGYEEGGQLTEKVRRKPYSVVLLDEIEKAHPDVFNILLQVLEDGRL
TDSKGRTVDFRNTILIMTSNVGASELKRNKYVGFNVQDEGQNYKDMKGKVMGELKRAFRPEFINRIDEIIVFHSLEKKHL
KEIVSLMSDQLTKRLKEQDLSIELTEAAKAKIADEGVDLEYGARPLRRAIQKHVEDRLSEELLKGNIEKGQQIVLDVEDG
EIVVKTTAATN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 58
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 6e-98 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_001485331.1 class III stress response-related ATPase VFG0079 Protein 0.0 79
clpC YP_001485331.1 class III stress response-related ATPase VFG0080 Protein 1e-149 54