Gene Information

Name : guaA (BPUM_0548)
Accession : YP_001485802.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 586366 - 587907 bp
Length : 1542 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAAATTTAGTAAATGAAATGATTTTGGTTCTAGATTTCGGCAGTCAGTACAATCAGTTGATCACACGCCGTATTCG
TGAATTTGGTGTGTACAGTGAGCTTCATCCGCACACTTTAACTGCTGAAGAAATTAAAGAAATGGCGCCTAAAGGAATCA
TCCTTTCTGGCGGACCAAACAGTGTTTATGATGAAGGATCTTTCCGCTGTGATGAAAAGATTTTTGATCTAGACATTCCG
GTTCTAGGCATTTGCTACGGCATGCAGCTCATGACTCACTATTTAGGCGGGAAAGTAGAAGCGGCAAGCCAGCGTGAATA
CGGAAAAGCGGATATCCACATTAATGGAACGCCTGCTTTATTTAAAGACCTTCCGACTGATCAAGTTGTTTGGATGAGCC
ATGGTGACCTCGTTGTTGAAGTACCAGAAGGCTTTACAGTTGATGCAACAAGTGCACATTGTCCAAACTCAGCGATGAGC
TTAGCTGAGAAGAATTTCTATGGCGTTCAGTTCCACCCAGAGGTTCGTCATTCTGAGTACGGAAATGACCTATTGAAAAA
CTTTGTCTTCGGCGTGTGTGATTGCGATGGCAAATGGTCAATGGAGAACTTCATTGAAATCGAAATGCAGAAAATCCGTG
AAACAGTAGGAGACAAACAAGTACTGTGCGCACTAAGCGGCGGTGTGGATTCATCTGTTGTGGCGGTATTGATCCACAAA
GCCATCGGTGATCAGCTGACATGTATTTTCGTTGACCACGGTCTTCTTCGCAAAGGCGAAGCAGAAGGGGTTATGAAGAC
ATTTAGCGAAGGTTTCAACATGAACGTGATTAAAGTAGATGCAAAAGATCGTTTCTTAAACAAGCTAAAAGGTGTGTCTG
ATCCTGAGCAAAAACGTAAAATCATCGGTAACGAATTCATCTATGTATTCGATGATGAATCGGACAAGCTAAAAGGAATC
GACTATTTAGCACAAGGAACACTTTACACAGATATCATTGAGAGCGGAACAGCAACGGCACAAACAATCAAATCTCACCA
CAACGTAGGTGGTCTTCCAGAAGACATGCAGTTCGAATTGATTGAGCCACTCAATACACTATTCAAGGATGAAGTCCGTG
CCCTAGGTTCAGAGCTGGGTATTCCTGACGACATCGTCTGGAGACAGCCATTCCCAGGTCCAGGACTAGGTATCCGTGTA
CTAGGTGAAATTTCTGAAGAAAAACTAGAAATCGTCCGTGAATCAGATGCAATTCTACGCGAAGAAATTGCCAACTTCGG
CCTTGAACGCGACATCTGGCAATACTTCACGGTTCTTCCAGACATCCGCAGCGTAGGTGTCATGGGTGACGCAAGAACAT
ACGACTACACAATCGGCATCCGTGCTGTTACTTCGATTGACGGTATGACGAGTGACTGGGCAAGAATCCCTTGGGATGTA
CTTGAAAAGATCTCAACTCGTATCGTGAATGAAGTGAAGCATGTGAACCGCGTGGTGTATGATATTACGAGTAAGCCGCC
TGCTACAATTGAGTGGGAATGA

Protein sequence :
MTNLVNEMILVLDFGSQYNQLITRRIREFGVYSELHPHTLTAEEIKEMAPKGIILSGGPNSVYDEGSFRCDEKIFDLDIP
VLGICYGMQLMTHYLGGKVEAASQREYGKADIHINGTPALFKDLPTDQVVWMSHGDLVVEVPEGFTVDATSAHCPNSAMS
LAEKNFYGVQFHPEVRHSEYGNDLLKNFVFGVCDCDGKWSMENFIEIEMQKIRETVGDKQVLCALSGGVDSSVVAVLIHK
AIGDQLTCIFVDHGLLRKGEAEGVMKTFSEGFNMNVIKVDAKDRFLNKLKGVSDPEQKRKIIGNEFIYVFDDESDKLKGI
DYLAQGTLYTDIIESGTATAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRALGSELGIPDDIVWRQPFPGPGLGIRV
LGEISEEKLEIVRESDAILREEIANFGLERDIWQYFTVLPDIRSVGVMGDARTYDYTIGIRAVTSIDGMTSDWARIPWDV
LEKISTRIVNEVKHVNRVVYDITSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 0.0 77
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 0.0 77
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 0.0 77
guaA NP_938969.1 GMP synthase Not tested Not named Protein 3e-136 53