Gene Information

Name : leuS (BPUM_2669)
Accession : YP_001487887.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 2682179 - 2684728 bp
Length : 2550 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
GTGGTACCGCGGGAACCAAAAAATCTCTCGTCCCTTTCCAGGGATGAGGGTTTTTTGTTGATTTTAGAAAAATCTGAATT
CTTGCAGTGGTCATCTGAGCAGATACAGCCGTACATATTAAAGGAGGTTTTCACATTGAGTTTTCAGCATCGGGAAATTG
AAAAGAAGTGGCAGGATTATTGGCTGACACATAAAACATTCGCCACATCTGACTCGGAAGATAAACCAAAGTTCTATGCA
CTTGATATGTTTCCATACCCATCAGGAGCAGGGCTTCATGTCGGGCATCCTGAGGGCTACACAGCAACGGATATTTTATC
ACGCATGAAACGTATGCAGGGATATGATGTTCTTCATCCAATGGGATGGGACGCATTTGGTCTTCCAGCAGAACAGTATG
CGCTAGATACAGGGAATGATCCGGCGGTCTTTACAGAAGAGAACATCAATAACTTCCGCCGACAAATTCAATCACTCGGG
TTCTCGTATGATTGGGATCGAGAAATCAACACGACTGATCCGAATTATTATAAATGGACACAATGGATTTTCTTGAAATT
GTACGAAAAGGGATTGGCGTATATCGATGAAGTACCAGTGAACTGGTGCCCAGCTCTTGGAACAGTCCTTGCAAATGAAG
AAGTCATTGATGGAAAAAGTGAACGCGGAGGACATCCAGTTGAAAGACGTCCGATGAAGCAATGGATGCTAAAGATTACG
GCTTATGCGGACAGGCTGTTAGAAGATTTAGAAGACATTGATTGGCCTGAAAGCATTAAAGATATGCAGCGTAACTGGAT
TGGACGTTCAGAAGGTGCACACGTTCATTTCGAAATAGAAGGACATGACGAACAGTTTACTGTATTTACAACACGTCCTG
ATACATTGTTTGGTGCAACCTATGCGGTACTTGCACCAGAACATGCACTGGTTGAAAAAATTACAACAGCTACTCAAAAA
GAGGCAGTCGAAGCATATATAAAAGAAATTCAATCTAAGAGCGACTTAGAGCGTACAGATCTTGCAAAAACAAAGACGGG
TATTTTCACTGGCGCTTATGCCGTCAATCCATTAAATGGTGAAAAGATGCCGATCTGGATTGCAGATTACGTGCTGGCTA
CTTATGGAACAGGGGCGATTATGGCGGTACCTGCCCATGATGAGCGTGACTATGAATTTGCCAAAACATTTGATCTTCCA
ATCAAGGCAGTTGTCGAAGGCGGAGACATTGAAGAAGAAGCTTACACAGGTGATGGAAAACACATCAACTCTGATTTCCT
TGATGGATTAGGAAAAGAAGAAGCGATTGAAAAAGTCATTGCATGGCTGGAAGAACATCAAAAAGGCGAAAAGAAAGTCA
CTTATCGTTTAAGAGATTGGCTATTTAGCCGTCAGCGTTATTGGGGTGAGCCAATTCCAATTATTCATTGGGAGGATGGA
ACGTCTTCAGCTGTTTCTGAGGAAGACCTTCCACTGATTTTGCCTAAGACGACTGAGATTAAGCCAAGTGGTACAGGTGA
ATCACCTTTAGCGAATATCAAAGATTGGGTTGAGGTTGTCGATCCTGTTACAGGTAAAAAAGGACGCCGTGAAACCAATA
CAATGCCGCAATGGGCAGGCAGCTGCTGGTATTTCTTACGTTATATTGACCCGCATAACTCAGAAGAACTTGCATCTCCT
GAGAAGTTAAAGAAATGGCTTCCGGTTGATGTATATATCGGCGGAGCAGAACATGCTGTACTTCATCTTCTATATGCACG
CTTCTGGCATAAGTTTTTGTATGATATTGGTGTTGTTCCAACAAAAGAACCTTTCATGAAATTGTTCAACCAAGGAATGA
TTCTTGGGGAAAATAATGAAAAAATGAGTAAATCAAAAGGAAATGTTGTCAATCCAGATGATATCGTAGAATCTCATGGT
GCGGATACTTTACGACTTTATGAAATGTTCATGGGACCTTTAGATGCATCAATCGCTTGGTCTGAAACAGGACTTGATGG
TGCTCGCCGTTTCCTTGATCGAGTATGGCGTCTCTTCACAAATGAAGATGGCACAATCAGTGATAAAGTAACGGAGCAAA
CTGGAGGCGCCTTAGAACGCAGCTATCATGAAACTGTGATGAAGGTAACAGACCATTATGAGGGACTGCGCTTCAATACA
GGGATTTCACAATTAATGGTGTTTATCAACGATGCCTACAAGGCTGATACATTGCCGAAAGAATATGCAGAAGGCTTTGT
GAAACTTCTTTCTCCAATTGCACCGCATCTAGCGGAAGAGCTTTGGAATAAACTTGGTCATGAAGGGTCTATTTCTTATG
AAGCATGGCCACAATATGACGAGTCAAAGCTTGTCGACGATGAAGTAGAAATTGTCGTACAGTTGAATGGGAAAGTGAAA
GCAAAATTAACTGTTCCTGCTGATGCCACTAAAGAACAATTAGAAGATCTTGCGAAAAGTGATGCACGTGTAAAAGAACA
GCTTGAAGGGAAAACCATTCGCAAAGTGATTGCGGTTCCTGGGAAGCTTGTCAATATTGTTGCGAATTAA

Protein sequence :
MVPREPKNLSSLSRDEGFLLILEKSEFLQWSSEQIQPYILKEVFTLSFQHREIEKKWQDYWLTHKTFATSDSEDKPKFYA
LDMFPYPSGAGLHVGHPEGYTATDILSRMKRMQGYDVLHPMGWDAFGLPAEQYALDTGNDPAVFTEENINNFRRQIQSLG
FSYDWDREINTTDPNYYKWTQWIFLKLYEKGLAYIDEVPVNWCPALGTVLANEEVIDGKSERGGHPVERRPMKQWMLKIT
AYADRLLEDLEDIDWPESIKDMQRNWIGRSEGAHVHFEIEGHDEQFTVFTTRPDTLFGATYAVLAPEHALVEKITTATQK
EAVEAYIKEIQSKSDLERTDLAKTKTGIFTGAYAVNPLNGEKMPIWIADYVLATYGTGAIMAVPAHDERDYEFAKTFDLP
IKAVVEGGDIEEEAYTGDGKHINSDFLDGLGKEEAIEKVIAWLEEHQKGEKKVTYRLRDWLFSRQRYWGEPIPIIHWEDG
TSSAVSEEDLPLILPKTTEIKPSGTGESPLANIKDWVEVVDPVTGKKGRRETNTMPQWAGSCWYFLRYIDPHNSEELASP
EKLKKWLPVDVYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFMKLFNQGMILGENNEKMSKSKGNVVNPDDIVESHG
ADTLRLYEMFMGPLDASIAWSETGLDGARRFLDRVWRLFTNEDGTISDKVTEQTGGALERSYHETVMKVTDHYEGLRFNT
GISQLMVFINDAYKADTLPKEYAEGFVKLLSPIAPHLAEELWNKLGHEGSISYEAWPQYDESKLVDDEVEIVVQLNGKVK
AKLTVPADATKEQLEDLAKSDARVKEQLEGKTIRKVIAVPGKLVNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 68