Gene Information

Name : hemC (BPUM_2456)
Accession : YP_001487679.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 2464703 - 2465638 bp
Length : 936 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
TTGCGTACAATTAAAGTAGGTTCTAGAAGAAGTAAGCTTGCAATTACACAAACAAAATGGGTCATTCAAAAGCTGTCTGA
ACTAAACCCTTCTTATTCTTTTGAAATAAAAGAGATTGTGACAAAGGGTGATCAAATTTTAGATGTAACCTTATCAAAGG
TTGGCGGAAAAGGACTGTTTGTCAAAGAAATTGAACAGGCGATGCTGAATCACGACATCGATATGGCAGTTCACAGTATG
AAGGATATGCCGGCTGCTCTTCCTGAAGGATTAGTCATTGGCTGTATTCCTGAGCGTGAAGATGTAAGGGACGCTCTTAT
TTCGAAGGATCATCTTCATCTACATGAGCTGCCAAAGGGTGCGATTGTGGGAACAAGCAGCTTACGGCGTAGTGCCCAGC
TTCTTCAGGAAAGACCAGATCTGAACATCAAATGGATTCGAGGAAACATTGATACACGATTGGAAAAGCTGAAAAATGAA
GAATATGATGCCATTATTTTAGCGGCTGCTGGTCTGTCCAGAATGGGCTGGAGTAAAGAGGTTGTGTCTGAATTTTTATC
TCCTGAGACTTGTCTGCCCGCAGTTGGCCAAGGCGCTTTGTCAATTGAGTGCCGCGGAGATGATGAAGAGCTGTTGCAGC
TCCTCGCTCAATTTACGAATGAATACACAAAGAAAACGGTTCTCGCTGAACGAGCCTTCCTCAAACAAATGGATGGCAGC
TGTCAGGTGCCGATTGCTGGATATGCAACAATGAATGAGCGCGATGAAATTGAACTGACGGGTCTTGTGGCATCTGCTGA
TGGACATACGATTATTCGAGAAACTGTATCAGGCACTGACCCTGAGGCAATTGGAACAGCATGTGCGAAGCAGATGGCTG
ATAAGGGAGCAAAGGATTTAATCGACAAGGTGAAAAAGGATCTGTCCTCCCAATGA

Protein sequence :
MRTIKVGSRRSKLAITQTKWVIQKLSELNPSYSFEIKEIVTKGDQILDVTLSKVGGKGLFVKEIEQAMLNHDIDMAVHSM
KDMPAALPEGLVIGCIPEREDVRDALISKDHLHLHELPKGAIVGTSSLRRSAQLLQERPDLNIKWIRGNIDTRLEKLKNE
EYDAIILAAAGLSRMGWSKEVVSEFLSPETCLPAVGQGALSIECRGDDEELLQLLAQFTNEYTKKTVLAERAFLKQMDGS
CQVPIAGYATMNERDEIELTGLVASADGHTIIRETVSGTDPEAIGTACAKQMADKGAKDLIDKVKKDLSSQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 8e-62 49
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 8e-62 49