Gene Information

Name : yrhB (BPUM_2360)
Accession : YP_001487586.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 2370046 - 2371194 bp
Length : 1149 bp
Strand : -
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGAAACGAAAAACAATGATGATACACAGCGGAACAACGGGTGATGAAAAAACGGGCGCTGTGTCTGTACCTATATACCA
AGTGAGCACCTATAAGCAGCCGAAAGCAGGCGAACATACAGGGTATGAATATTCAAGAACAGCGAACCCAACAAGAACGG
CACTAGAAACCGCCATTCGTGACCTTGAAGGAGGAGCAAACGGCTACGCATTTGGTTCAGGAATGGCTGCCATTACGGCA
GTGATGATGCTGTTTAACAGTGGAGATCATATTGTCCTGACAGATGACGTTTACGGCGGAACGTACCGCGTCATCACAAA
GGTACTCAATCGTATTGACATTCAAGCGACCTTTGTTGACACAAGTGATCCTGAAGCAGTGAAAAAGGCGATTTTACCTG
AAACAAAAGCGGTTTACATTGAATCACCAACCAATCCTTTACTCAAAATGACTGACCTCAAAGCAGTCGGCCAATTGACA
AAAGAAGCTAACATCTTAATGATTGTTGATAATACATTTTTCACACCTTATTTCCAAAGACCGATTGAATATGGGGCAGA
CATTGTCCTGCATAGTGCCACTAAATATTTAGGTGGTCACAGTGACGTCGTAGGTGGGCTTGTTGTAACAGCGACGGAAG
AGCTTGGGGAAGAACTGCATTTTGTTCAAAATTCTACAGGTGGAATCCTTGGACCGCAGGATTCATGGCTTCTCATGAGA
GGAATCAAAACACTTGGACTAAGAATGGAAGCACATCAGCAAAATGCACAGAAAATCGCTGAGTTTTTAGAACAACATCC
AGCAGTCACACGTGTTTATTACCCAGGTCTTGATGCTCATCCCGGACATGAACTTGCAAAAACGCAAGCATCAGGCTACG
GCGGTATGATCTCTTTTGATATTGGAAAAGAAGAACATGTCGATGTGTTTTTAAGTCAGCTTAAGCTGTTTACGATCGCA
GAAAGCCTTGGAGCGGTTGAAAGCTTAATTTCTGTTCCTGCTCGAATGACTCATGCGTCCATTCCAAAAGACCGTCGCGA
GGAGCTTGGCATCACTGATGGGTTAATTCGTATATCCGTCGGGATTGAAGATGTGGATGATTTACTGAATGATATGAAGC
AGGGACTAAACGCACTAGTGAATGGATAG

Protein sequence :
MKRKTMMIHSGTTGDEKTGAVSVPIYQVSTYKQPKAGEHTGYEYSRTANPTRTALETAIRDLEGGANGYAFGSGMAAITA
VMMLFNSGDHIVLTDDVYGGTYRVITKVLNRIDIQATFVDTSDPEAVKKAILPETKAVYIESPTNPLLKMTDLKAVGQLT
KEANILMIVDNTFFTPYFQRPIEYGADIVLHSATKYLGGHSDVVGGLVVTATEELGEELHFVQNSTGGILGPQDSWLLMR
GIKTLGLRMEAHQQNAQKIAEFLEQHPAVTRVYYPGLDAHPGHELAKTQASGYGGMISFDIGKEEHVDVFLSQLKLFTIA
ESLGAVESLISVPARMTHASIPKDRREELGITDGLIRISVGIEDVDDLLNDMKQGLNALVNG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-108 57
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-106 56
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-78 44

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yrhB YP_001487586.1 cystathionine beta-lyase BAC0207 Protein 6e-71 43