Gene Information

Name : thyA (BPUM_1916)
Accession : YP_001487146.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 1970086 - 1970880 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAATACAAAGAGTTATGCCGTCATGTATTACAGCACGGGGATGAAAAAGGTGACAGAACGGGAACAGGCACAAT
CAGCACGTTCGGTTACCAGATGAGATTTGATTTGCAGGAAGGATTTCCACTTTTAACAACAAAGAAATTGCACCTGAAAT
CAATTATTCATGAGTTGCTTTGGTTTTTAAAAGGTGATACAAATGTCAAATACCTTCAGGAAAATGGTGTCCGTATATGG
AATGAATGGGCAGATGAAAATGGCGAACTAGGCCGTGTGTACGGAGCGCAGTGGCGATCTTGGGCTAGTGGAGACGGTGA
GACTGTGGATCAGATCACAAAGCTGATCCACGATATCGAGCATAATCCCAATTCAAGAAGACTAATCGTCAGCGCTTGGA
ACCCGGGTGAAATTGATCAAATGGCGCTGCCACCATGTCATTGTCTGTTTCAATTTTACGTATCAAACGGAAAGCTTTCT
TGCCAGCTTTATCAAAGATCGGCAGATATCTTTTTAGGTGTTCCATTTAATATTGCTTCATATGCTCTTCTTACGATGAT
GATTGCCAAAGTCACAAATCTTGAGCCAGGAGAGTTTGTTCATACGCTAGGGGATGCTCATATTTATCAGAATCATCTTC
CTCAGGTGAACATGCAACTAGAGCGTGAGGAACGTGCGCTTCCGCAGCTTCGCATCACAAGAGATGTGAAGAGCATTTTT
GATTTCACGTTCGATGATTTTGTACTTGAAAATTATGATCCGCATCCGCACATTAAAGGAGAAGTCAGTGTATGA

Protein sequence :
MKQYKELCRHVLQHGDEKGDRTGTGTISTFGYQMRFDLQEGFPLLTTKKLHLKSIIHELLWFLKGDTNVKYLQENGVRIW
NEWADENGELGRVYGAQWRSWASGDGETVDQITKLIHDIEHNPNSRRLIVSAWNPGEIDQMALPPCHCLFQFYVSNGKLS
CQLYQRSADIFLGVPFNIASYALLTMMIAKVTNLEPGEFVHTLGDAHIYQNHLPQVNMQLEREERALPQLRITRDVKSIF
DFTFDDFVLENYDPHPHIKGEVSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 8e-79 61