Gene Information

Name : yjcJ (BPUM_1120)
Accession : YP_001486364.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 1198435 - 1199613 bp
Length : 1179 bp
Strand : +
Note : catalyzes the formation of L-homocysteine from cystathionine

DNA sequence :
ATGACCACACATGATTGGACATTCGAAACCCAACTCGTTCATAACGCATTCAAAACAGACCGTTCAACAGGTGCAGTCAG
TGTGCCGATTCAGCATGCGTCCACCTTTCATCAAAGCAGCTTTGATGATTTTGGTCAATATGACTACTCAAGATCGGGGA
CTCCTACACGTCAAGCGTTAGAGGATACGATTGCGGCGCTAGAAGGAGGAACGAGAGGGCTTGCTTTTGCATCTGGCATG
GCAGCCATCTCCACTGCTTTTCTTCTATTATCAAAAGGAGATCACGTCCTTGTCACAAGAGATGTGTATGGTGGTACATT
TCGTATGATCACCCAAGTCCTTTCGAGATTCGGCATTGAGCATACCTTTGTGGACATGACGGATTTGAATGAAGTCAAAA
AAGGCATTCAATCGAATACGAAGGTCATTTACATGGAAACACCGTCAAACCCGACGCTAGGAATTACGGATATAGAGGGC
GTCGTCCAGCTTGCGAAAGAACATGACTGTCTGACATTTTTAGATAATACATTTTTAACACCGGCTCTTCAGCGTCCGCT
CGACCTTGGCGTTGACGTTGTCCTGCACAGCGCAACGAAATTTTTGAGCGGTCATAGTGATGTACTGTCAGGCTTAGCGG
TGGTGAAAGATGAGAAGCTGGGAGAGGAACTCTATTCGCTGCAAAACTCATTCGGTGCGGTCCTTGGCGTGCAGGATTGC
TGGCTTGTGTTAAGAGGGTTAAAAACCCTTCAGGTGAGATTGGAAAAAGCCAGCCAAACGGCATTTGAACTCGCTTCATT
TCTCAAAGAACATCCTGCGGTGAAAAAAGTATACTATCCAGGCTTAGATAACCATCTAGGAGCAGACATTCAGCGAAAGC
AAGCAAGCGGAGCTGGAGCCGTTCTCTCATTTGAATTAGAAAACGAAGCAGCAGTCAAAGAATTAGTGGACGCTGTCACA
TTACCTGTATTCGCCGTCAGCCTTGGCGCCGTCGAATCCATTCTGTCATACCCAGCCAAAATGTCACATGCGGCTATGCC
AAAAGAAGAAAGAGAAAAAAGAGGAATTACAGATGGGTTGCTTCGTTTAAGTGTTGGAGTTGAAAACGGAGAAGACCTCA
AACGCGACTTCAAACAAGCACTCGATCAATTAAAGCCCGTTCTTGTCAACCAATCATGA

Protein sequence :
MTTHDWTFETQLVHNAFKTDRSTGAVSVPIQHASTFHQSSFDDFGQYDYSRSGTPTRQALEDTIAALEGGTRGLAFASGM
AAISTAFLLLSKGDHVLVTRDVYGGTFRMITQVLSRFGIEHTFVDMTDLNEVKKGIQSNTKVIYMETPSNPTLGITDIEG
VVQLAKEHDCLTFLDNTFLTPALQRPLDLGVDVVLHSATKFLSGHSDVLSGLAVVKDEKLGEELYSLQNSFGAVLGVQDC
WLVLRGLKTLQVRLEKASQTAFELASFLKEHPAVKKVYYPGLDNHLGADIQRKQASGAGAVLSFELENEAAVKELVDAVT
LPVFAVSLGAVESILSYPAKMSHAAMPKEEREKRGITDGLLRLSVGVENGEDLKRDFKQALDQLKPVLVNQS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-82 51
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 8e-89 50
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 2e-87 49

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yjcJ YP_001486364.1 cystathionine beta-lyase BAC0207 Protein 2e-60 41