Gene Information

Name : yjcI (BPUM_1119)
Accession : YP_001486363.1
Strain : Bacillus pumilus SAFR-032
Genome accession: NC_009848
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 1197320 - 1198438 bp
Length : 1119 bp
Strand : +
Note : catalyzes the formation of cysteine from cystathionine; in B. subtilis also has O-acetylhomoserine thiolyase activity

DNA sequence :
ATGACAGAACATGTGGAAACGACATTAGCGCAAATTGGAAACCGTAGCGAAGAGGCGACTGGTACGGTCAGTCCCCCCGT
TTATCTTTCAACAGCATACAGACATAGAGGCATAGGGGAATCAACCGGATTTGATTACATTCGAACGAAAAACCCAACAA
GGCAGCTTGTAGAGGATGCGATTGCTTCACTCGAAGAAGGGACGGCCGGATTTGCCTTCAGTTCGGGAATGGCTGCGATC
CAAACGATCAAGGCGCTATTTGAAAGCGGTGATGAACTCATCGTCTCATCAGACCTATATGGCGGTACATACCGTTTGTT
TGAAAACGAATGGAAAAAGTACGGCTTACGTTTTCTTTACGATGATTTTTCAGATGAAGACTGTTTACGCTCTAAAATCA
CGCCAAACACAAAAGCAGTCTTTATTGAGACGCCGACAAATCCACTTATGCAAGAAGCGGATATTCAAAAAATAGCGAAG
ATTGCAAAAGAACATGGCGCTTTGGTCATTGTCGATAACACCTTTTACACTCCCGTTTTGCAAAAGCCGATTACGCTTGG
AGCGGACATTGTGATTCATAGCGCAACCAAATATTTAGGCGGACATAATGACGTTCTTGCAGGGCTTGTCGTCACAAAAG
GAGAGCAGTTGTCTGAAGACATGTTCCAGCATCAAAATGCGATTGGAGCAGTTCTATCACCATTTGACTCATGGCTATTA
ATGAGAGGGATGAAAACACTGGCTCTTAGAATGCGCCAGCACGAAGCAAATGCGCAGGAGCTAGCGGAGTTTTTAAAGAA
ACAGCCAGAAATTCAAGATGTCCTTTACCCAGGCAAGGGAGGAATGCTGTCTTTCCGTGTAGCCGAAGAGGACTGGGTCA
ATCCATTTTTAAAGCAGCTGAAAACGATTTGTTTTGCTGAAAGTCTTGGAGGAATTGAAAGTTTTATCACGTATCCTGCG
ACGCAAACGCACATGGATATTCCTGAGGAAATTCGCATTGCAAACGGTGTGTGTAACAAACTGCTCCGTTTCTCCGTTGG
TATTGAGCATGTAGATGACCTGAAGGCAGACCTAAAGCAGGCACTATCACAAGTAAAAGAGGAGGTACATGCCAAATGA

Protein sequence :
MTEHVETTLAQIGNRSEEATGTVSPPVYLSTAYRHRGIGESTGFDYIRTKNPTRQLVEDAIASLEEGTAGFAFSSGMAAI
QTIKALFESGDELIVSSDLYGGTYRLFENEWKKYGLRFLYDDFSDEDCLRSKITPNTKAVFIETPTNPLMQEADIQKIAK
IAKEHGALVIVDNTFYTPVLQKPITLGADIVIHSATKYLGGHNDVLAGLVVTKGEQLSEDMFQHQNAIGAVLSPFDSWLL
MRGMKTLALRMRQHEANAQELAEFLKKQPEIQDVLYPGKGGMLSFRVAEEDWVNPFLKQLKTICFAESLGGIESFITYPA
TQTHMDIPEEIRIANGVCNKLLRFSVGIEHVDDLKADLKQALSQVKEEVHAK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-72 45
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-73 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yjcI YP_001486363.1 cystathionine gamma-synthase BAC0207 Protein 3e-57 42