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Name : guaA (P9215_00351) Accession : YP_001483240.1 Strain : Prochlorococcus marinus MIT 9215 Genome accession: NC_009840 Putative virulence/resistance : Unknown Product : GMP synthase Function : - COG functional category : F : Nucleotide transport and metabolism COG ID : COG0519 EC number : 6.3.4.1 Position : 34763 - 36349 bp Length : 1587 bp Strand : + Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway DNA sequence : ATGAGTCAAACATCTTTAAAAAAAGAACGAGATCCTTCAATATTAATTCTGGATTTCGGATCTCAATATTCTGAATTGAT TGCAAGAAGAATTAGAGAAACTAATGTTTTTTCTCTTGTAGTAAGTAATTGCATTTCAATTAAGGAAATTAATAATATTA ATCCCAAAGGGATCATTTTGAGTGGAGGTCCAAATTCTGTATATGAGCAAAATGCGCCTAAATGTGATGAAAAAATTTTT AATTTAGGAATTCCTATTCTTGGTATATGCTATGGAATGCAATTAATGGTCAAAGAACTTGGTGGATCTGTTATCCCAGC AACAAAAAAAGCTGAATATGGTAGAGCACCAATAAATATAGACCAAGAATCTGATCTCCTTTCTGATGTACAAGATAAAT CTATAATGTGGATGAGTCATGGCGATTCTATTAAATGTTTGCCTGTTGGATTTAATAAAATTGCTCATACCGAGAACACA CTCCATGCAGCAATTTCAAATGATTTAAAGAAATTATTTGGCGTACAGTTTCATCCTGAAGTTATTCATTCAGAGTATGG GATGACGGTAATTAAAAATTTTGTTTATAAAATCTCTTGTTGTGCGGCTGATTGGACAACCGAAACCTATATTGAGGAAA CTATTCCTAGGATAAGAGAACAAGTTGGCAATAAAAAAGTTTTGCTTGCCTTGTCAGGAGGAGTTGATTCATCAACTCTT GCTTTTCTTCTCAATAAAGCAATTGGAAACCAGCTCACATGCATGTTTATTGACCAAGGTTTTATGAGAAAAGGTGAACC AGAATTTTTAATGAATTTTTTTGATAAGAAATTTCATATAAAAGTTGAATATATTAATGCCAGGAAAAGGTTTATTTCTA AATTAAAAGGGATTACTGAACCAGAACAAAAAAGAAAAATTATTGGTGAAGAATTTATCAGGGTATTTGAAGAAGAAAGC AATAGGTTGGGACCTTTTCAGTATTTAGCTCAAGGTACTCTTTATCCTGATGTTATTGAGAGTGCTGGGACTAATATTGA TCCCAAAACAGGTGAAAGAATAGCCGTAAAAATAAAGAGTCATCATAATGTGGGTGGATTGCCAAAAGATTTACAATTTA AATTAGTTGAGCCATTAAGAAAACTTTTCAAGGACGAAGTCCGACAAGTTGGAGCTGCTTTAGGTTTGCCGGCTGAAATT ATAAAAAGGCATCCATTCCCAGGTCCAGGATTAGCTATAAGAATTTTGGGAGAGGTGAATAATGAAAAACTTGATTGTTT GAGAGATGCAGATTGGATAGTAAGAGATGAAATTAAAAAAGCAGGTCTTTACAATGAGATTTGGCAAGCTTTTGCAGTAT TGTTGCCTGTAAAAACCGTAGGAGTTATGGGTGATAAAAGGACTTATGCGTGGCCAATAGTTTTACGTTGTGTATCAAGT GAAGATGGGATGACAGCCGATTGGTCAAAAATTCCCTTTAAGATTTTGGAGAGGATTGCAAATAGAATCGTAAATGAAGT AATTTCAGTAAATAGAGTTGTTTATGATATTACAAGTAAACCTCCTGGAACTATTGAGTGGGAATGA Protein sequence : MSQTSLKKERDPSILILDFGSQYSELIARRIRETNVFSLVVSNCISIKEINNINPKGIILSGGPNSVYEQNAPKCDEKIF NLGIPILGICYGMQLMVKELGGSVIPATKKAEYGRAPINIDQESDLLSDVQDKSIMWMSHGDSIKCLPVGFNKIAHTENT LHAAISNDLKKLFGVQFHPEVIHSEYGMTVIKNFVYKISCCAADWTTETYIEETIPRIREQVGNKKVLLALSGGVDSSTL AFLLNKAIGNQLTCMFIDQGFMRKGEPEFLMNFFDKKFHIKVEYINARKRFISKLKGITEPEQKRKIIGEEFIRVFEEES NRLGPFQYLAQGTLYPDVIESAGTNIDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRQVGAALGLPAEI IKRHPFPGPGLAIRILGEVNNEKLDCLRDADWIVRDEIKKAGLYNEIWQAFAVLLPVKTVGVMGDKRTYAWPIVLRCVSS EDGMTADWSKIPFKILERIANRIVNEVISVNRVVYDITSKPPGTIEWE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| guaA | YP_001331415.1 | GMP synthase | Not tested | vSa¥á | Protein | 7e-139 | 54 |
| SAMSHR1132_03620 | YP_005324884.1 | GMP synthase | Not tested | vSa¥á | Protein | 6e-139 | 54 |
| SAPIG0468 | YP_005733278.1 | GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) | Not tested | SAPI-S0385 | Protein | 5e-139 | 54 |
| guaA | NP_938969.1 | GMP synthase | Not tested | Not named | Protein | 2e-127 | 50 |
