Gene Information

Name : guaA (P9215_00351)
Accession : YP_001483240.1
Strain : Prochlorococcus marinus MIT 9215
Genome accession: NC_009840
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.4.1
Position : 34763 - 36349 bp
Length : 1587 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAGTCAAACATCTTTAAAAAAAGAACGAGATCCTTCAATATTAATTCTGGATTTCGGATCTCAATATTCTGAATTGAT
TGCAAGAAGAATTAGAGAAACTAATGTTTTTTCTCTTGTAGTAAGTAATTGCATTTCAATTAAGGAAATTAATAATATTA
ATCCCAAAGGGATCATTTTGAGTGGAGGTCCAAATTCTGTATATGAGCAAAATGCGCCTAAATGTGATGAAAAAATTTTT
AATTTAGGAATTCCTATTCTTGGTATATGCTATGGAATGCAATTAATGGTCAAAGAACTTGGTGGATCTGTTATCCCAGC
AACAAAAAAAGCTGAATATGGTAGAGCACCAATAAATATAGACCAAGAATCTGATCTCCTTTCTGATGTACAAGATAAAT
CTATAATGTGGATGAGTCATGGCGATTCTATTAAATGTTTGCCTGTTGGATTTAATAAAATTGCTCATACCGAGAACACA
CTCCATGCAGCAATTTCAAATGATTTAAAGAAATTATTTGGCGTACAGTTTCATCCTGAAGTTATTCATTCAGAGTATGG
GATGACGGTAATTAAAAATTTTGTTTATAAAATCTCTTGTTGTGCGGCTGATTGGACAACCGAAACCTATATTGAGGAAA
CTATTCCTAGGATAAGAGAACAAGTTGGCAATAAAAAAGTTTTGCTTGCCTTGTCAGGAGGAGTTGATTCATCAACTCTT
GCTTTTCTTCTCAATAAAGCAATTGGAAACCAGCTCACATGCATGTTTATTGACCAAGGTTTTATGAGAAAAGGTGAACC
AGAATTTTTAATGAATTTTTTTGATAAGAAATTTCATATAAAAGTTGAATATATTAATGCCAGGAAAAGGTTTATTTCTA
AATTAAAAGGGATTACTGAACCAGAACAAAAAAGAAAAATTATTGGTGAAGAATTTATCAGGGTATTTGAAGAAGAAAGC
AATAGGTTGGGACCTTTTCAGTATTTAGCTCAAGGTACTCTTTATCCTGATGTTATTGAGAGTGCTGGGACTAATATTGA
TCCCAAAACAGGTGAAAGAATAGCCGTAAAAATAAAGAGTCATCATAATGTGGGTGGATTGCCAAAAGATTTACAATTTA
AATTAGTTGAGCCATTAAGAAAACTTTTCAAGGACGAAGTCCGACAAGTTGGAGCTGCTTTAGGTTTGCCGGCTGAAATT
ATAAAAAGGCATCCATTCCCAGGTCCAGGATTAGCTATAAGAATTTTGGGAGAGGTGAATAATGAAAAACTTGATTGTTT
GAGAGATGCAGATTGGATAGTAAGAGATGAAATTAAAAAAGCAGGTCTTTACAATGAGATTTGGCAAGCTTTTGCAGTAT
TGTTGCCTGTAAAAACCGTAGGAGTTATGGGTGATAAAAGGACTTATGCGTGGCCAATAGTTTTACGTTGTGTATCAAGT
GAAGATGGGATGACAGCCGATTGGTCAAAAATTCCCTTTAAGATTTTGGAGAGGATTGCAAATAGAATCGTAAATGAAGT
AATTTCAGTAAATAGAGTTGTTTATGATATTACAAGTAAACCTCCTGGAACTATTGAGTGGGAATGA

Protein sequence :
MSQTSLKKERDPSILILDFGSQYSELIARRIRETNVFSLVVSNCISIKEINNINPKGIILSGGPNSVYEQNAPKCDEKIF
NLGIPILGICYGMQLMVKELGGSVIPATKKAEYGRAPINIDQESDLLSDVQDKSIMWMSHGDSIKCLPVGFNKIAHTENT
LHAAISNDLKKLFGVQFHPEVIHSEYGMTVIKNFVYKISCCAADWTTETYIEETIPRIREQVGNKKVLLALSGGVDSSTL
AFLLNKAIGNQLTCMFIDQGFMRKGEPEFLMNFFDKKFHIKVEYINARKRFISKLKGITEPEQKRKIIGEEFIRVFEEES
NRLGPFQYLAQGTLYPDVIESAGTNIDPKTGERIAVKIKSHHNVGGLPKDLQFKLVEPLRKLFKDEVRQVGAALGLPAEI
IKRHPFPGPGLAIRILGEVNNEKLDCLRDADWIVRDEIKKAGLYNEIWQAFAVLLPVKTVGVMGDKRTYAWPIVLRCVSS
EDGMTADWSKIPFKILERIANRIVNEVISVNRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 5e-139 54
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-139 54
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 6e-139 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-127 50