Gene Information

Name : lysS (P9215_18921)
Accession : YP_001485091.1
Strain : Prochlorococcus marinus MIT 9215
Genome accession: NC_009840
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1628823 - 1630361 bp
Length : 1539 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
TTGTCTGAAATAAAAGAAGCACGCTTACAAAAAGCTAGGTCACTCGTAAGTAAAGGATTCGCTTCTTACGCACAGAGTTT
TAAGGTATCAAATACTACCAGTTTCCTTCTTCAAGAATTTGATTATTTAGAAAATGGTCAAGAGGCAGACTTCAGTGTCT
CTGTTGCTGGTAGAGTCTTGGCAAAAAGGGTAATGGGTAAAATTGCCTTTTTCACAATAAGCGATCAAGAAGGTCAGATT
CAGCTTTATCTAGATAAAAGGATTATTAATTTAAATTTAGAAAAACAAAAATTACTTTCTTTTGAAGATATCAAGGAAAT
AGTAGATATTGGTGATTGGATAGGTGTATACGGAACTATTAAAAAAACTAACAAAGGTGAGCTTTCAATTAAAGTAGAAA
AATGGGAAATGTTATCCAAATCATTACAACCTTTACCAGATAAGTGGCATGGATTGACAGATATTGAAAAAAGATATAGA
CAACGTTATCTAGATTTAATAGTAAATCCTCACTCTAAAAATGTATTTAAAACAAGAGCAAAATGTATAAGTTTTATAAG
AAAATGGCTAGATAATAGAAATTTTTTAGAGATAGAGACTCCAATTCTGCAATCTGAGGCTGGCGGTGCTGAAGCAAGAC
CATTTATAACTCATCACAATACATTAGATATTCCGCTCTATCTAAGAATAGCTACAGAATTACATTTAAAAAGAATGGTT
GTTGGAGGGTTTGAAAAAGTATATGAAATGGGAAGAATCTTCCGTAATGAGGGGATAAGTACAAGACATAATCCGGAATT
CACTTCAGTTGAAATTTATGAAGCTTATTCTGATTATTTCGATATGATGAATTTAACTGAAGAATTGATTAAAGATGTCG
TAGCTGATTCGTGTGGGTCTTTAATTATAAATTATCAAAATAAAGAAATTGATTTTTCTAAACCTTGGTTAAGAATTTCA
ATGAAAGATATTGTCAAAAAATATACAGGTATTGATTTTGATTCTTTCAGTGGAGACTTTCTAGCAGCAAAACAAGCCGT
TAAAAATATAAATGTTGATCTCTCTAACAAAGTGAATACTATGGGAAGACTTTTAAATGAGGTCTTCGAGCAAAAAGTAG
AATCAAAACTTATAGAACCCACTTTTGTTATCGATTATCCTGTTGAGATTTCTCCTTTAGCTAGGCCGCATTTTGATAAT
AAAGAAATAGTTCAGAGATTTGAATTATTTATTGTTGGGCGAGAGTTGGCAAATGCGTTTAGTGAGTTGATAGATCCAGT
AGATCAAAGAGAAAGAATGCAATTACAGCAATCTCTTAGAGATGAAGGAGATCTGGAGGCTCACTGTATAGATGAAGATT
TCTTGAATGCTTTAGAGATTGGCATGCCGCCAACTGGAGGATTAGGTATAGGTATTGATAGGTTAATTATGTTAATTACT
AATAGTGCATCAATTAGAGATGTAATCCCTTTCCCATTGTTAAAACCAGAAATAACTTCCAAAAAAAGTGAAAAATTACC
CTTGAATGAAGTAAAATAA

Protein sequence :
MSEIKEARLQKARSLVSKGFASYAQSFKVSNTTSFLLQEFDYLENGQEADFSVSVAGRVLAKRVMGKIAFFTISDQEGQI
QLYLDKRIINLNLEKQKLLSFEDIKEIVDIGDWIGVYGTIKKTNKGELSIKVEKWEMLSKSLQPLPDKWHGLTDIEKRYR
QRYLDLIVNPHSKNVFKTRAKCISFIRKWLDNRNFLEIETPILQSEAGGAEARPFITHHNTLDIPLYLRIATELHLKRMV
VGGFEKVYEMGRIFRNEGISTRHNPEFTSVEIYEAYSDYFDMMNLTEELIKDVVADSCGSLIINYQNKEIDFSKPWLRIS
MKDIVKKYTGIDFDSFSGDFLAAKQAVKNINVDLSNKVNTMGRLLNEVFEQKVESKLIEPTFVIDYPVEISPLARPHFDN
KEIVQRFELFIVGRELANAFSELIDPVDQRERMQLQQSLRDEGDLEAHCIDEDFLNALEIGMPPTGGLGIGIDRLIMLIT
NSASIRDVIPFPLLKPEITSKKSEKLPLNEVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-99 46

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001485091.1 lysyl-tRNA synthetase VFG1668 Protein 6e-100 46