Gene Information

Name : lysS (C8J_0376)
Accession : YP_001481952.1
Strain : Campylobacter jejuni 81116
Genome accession: NC_009839
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 374819 - 376324 bp
Length : 1506 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTTTGATAATATTTTAGAGCAGCAAAGAATAGAAAAAGCCAAGGAATTAAAAAATTTAGGGATCAATCCTTATCCTCA
TTTTTTAGAAAAAGAAATGTCTTTAAAGACTTTTAAGGATAAATTTTCTTATATTTTAGAGCAAGTTGAAAAAAGAGATG
AAAGTGTCAATGCTGTTGTTGCAGGACGTTTGAAACTTTTGCGTATAGCTGGGAAATCGATTTTTGCAAACATTGAAGAT
GAAGATACAAATTTGCAAATTTATTTTAATAAAGATAGTGTAGGTGAAGAACTTTATGCGATTTTGAAAAAGAATTTAGA
AGTAGGTGATATTGTTTTGGTTAAAGGTTTTCCTTTTGTAACTAAAACAGGTGAGTTTAGTTTGCATGCAAGTGAAGTAA
AACTCGCTACAAAAGCTATTGTTCCTTTACCTGAAAAATATCATGGATTAACAGATATTGAGCAAAGATATCGTAAACGT
TATGTTGATATGATAATGAATGCAGAAGTTAGAAAAGATTTTTTAGTGCGTTCTAAAGTGGTGAGTTTGATTCGTCATTT
TTTTGAAAATAAAGGCTTTTTAGAAGTAGAAACTCCTATGATGCATCCGATTGCAGGTGGAGCAAACGCTAAGCCTTTTG
TAACTTTTCACAATTCTTTAGGCGTAGAAAGATTTTTAAGAATTGCTCCAGAACTTTATCTTAAAAGACTTGTAGTGGGT
GGTTTTGAGGCAGTTTTTGAAATCAATCGTTGTTTTAGAAACGAAGGTATGGATTTAACCCATAATCCTGAATTTACAAC
TATAGAATTTTATTGGGCTTATCATAATTATAAAGATTTAATGGATTTAACTGAAGAACTTTTTGCTTTACTTTTAGATA
AACTTAATTTGGGAAAAACAATAGAATTTGATGGAAAAATGATAGATTTTTCTAAACCTTTTGAAAGAATTACTTACAAA
GATGCACTTTGTAAATATGGTGGTTTGGATAGGGATTTAATTGAAGATAAGGAAAAAATTCTTACTAAATTAAAAGTAGA
TGGTTTTGAAGCGAATGAAAAGCTTGAACTTGGACATTTACAAGCTGAACTTTTTGATAATTATGTGGAAGAAAAATTGA
TCAATCCTACTTTTGTGATTGATTTTCCTATTTCCATAAGTCCTTTATCAAGACGTAGCGATGAGGATTCTCAGATTGCT
GAGAGATTTGAGTTGTTTATTTGTGGAAGAGAATTGGCAAATGGTTTTAATGAGCTTAATGATCCTCTTGATCAATATGA
GAGATTTTTAAAACAAATTGAAGCTAAAAATGCAGGCGATGAAGAGGCTTGCGAAATGGATGAAGATTTTGTAAATGCTT
TGGGTTATGGAATGCCTCCAACGGCAGGGCAGGGTATAGGTATAGATAGACTTGTTATGCTTTTGACAAATAAAAAATCT
ATTCGAGATGTGATATTGTTTCCTGCAATGCGTCCATTAAAATCAGAACTAAAGGAGAAAGAATGA

Protein sequence :
MFDNILEQQRIEKAKELKNLGINPYPHFLEKEMSLKTFKDKFSYILEQVEKRDESVNAVVAGRLKLLRIAGKSIFANIED
EDTNLQIYFNKDSVGEELYAILKKNLEVGDIVLVKGFPFVTKTGEFSLHASEVKLATKAIVPLPEKYHGLTDIEQRYRKR
YVDMIMNAEVRKDFLVRSKVVSLIRHFFENKGFLEVETPMMHPIAGGANAKPFVTFHNSLGVERFLRIAPELYLKRLVVG
GFEAVFEINRCFRNEGMDLTHNPEFTTIEFYWAYHNYKDLMDLTEELFALLLDKLNLGKTIEFDGKMIDFSKPFERITYK
DALCKYGGLDRDLIEDKEKILTKLKVDGFEANEKLELGHLQAELFDNYVEEKLINPTFVIDFPISISPLSRRSDEDSQIA
ERFELFICGRELANGFNELNDPLDQYERFLKQIEAKNAGDEEACEMDEDFVNALGYGMPPTAGQGIGIDRLVMLLTNKKS
IRDVILFPAMRPLKSELKEKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 7e-105 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001481952.1 lysyl-tRNA synthetase VFG1668 Protein 4e-105 47