Gene Information

Name : guaA (C8J_1191)
Accession : YP_001482767.1
Strain : Campylobacter jejuni 81116
Genome accession: NC_009839
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1197394 - 1198929 bp
Length : 1536 bp
Strand : +
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAAAAAAGCAGATATTTTAGTTTTAGACTTTGGCTCTCAATACACTCAGCTTATAGCAAGACGCTTAAGGGAACAAGG
AGTTTATGCAGAAATTTTACCTTTTAATGTGAGCTTAGCTGATATTAAGGCGAAAGAACCAAAAGGTATTATTTTAAGCG
GAGGTCCAGCAAGCGTATATGCAACTGATGCGTATTTTTGCGATAAAGGTATATTTGACTTAGGTTTACCTATTCTTGGA
ATTTGTTATGGTATGCAGCTTATGGCACATCATTACAAAGCTACAGTAGCACCTGCAGGACATAAAGAATACGGCAAAGC
AAACATAGAAGTTAAAAAAGATAGCGCTTTGTTTAAAAATCTTCCAAAAAAACAAACTGTTTGGATGAGTCATTCTGATA
AGGTAGAAAATTTACCTCAAGGTTTTGAAGTTTTAGCCACAAGTGAAAATAGTCCTTTTTGTGTTTTTGGAAATGAAGAT
AAGAAATTCTTTGCTCTACAATTTCACCCAGAAGTACAACACAGTGAATTTGGCAAAAATATCTTAAAAAATTTTGCTAA
ATACGCTTGCAATTGTGAAAGCGTTTGGAATATGGGTTCTTTTGCAAAAACTCAAGCAGAAAAAATCCGTGAAGAAGTAG
GCAGTGATAAAGTGCTTTGCGCAGTAAGTGGCGGAGTAGATAGTAGCGTAGTTGCTGCACTTTTAGCTAGCGCTATAAAA
GAGCAAGTTATAGTAGTTTTTGTAGACAATGGACTTTTAAGAAGTGGAGAAAAAGAACAAGTTGAATTTATGTTTAAAAA
TACCTTAGGTATCGATCTTATCAGCATTGATGCAAGTGAAATTTTCCTAAGTCGCTTGGCTAATGTTAGAGATCCTGAGC
AAAAAAGAAAAATCATAGGAAATACCTTTATAGAAGTTTTTGAAGAAGAAGCAAAAAAACATAAAGATGTAAAATATCTC
GCTCAAGGCACACTTTATACTGATATCATAGAAAGTTCTGTTGTAGGTGCAAGCAAAACCATTAAAAGCCATCATAATGT
AGGGGGCTTACCTGAAAAAATGAATCTTAAACTCATAGAGCCTTTAAAAGAAATTTTTAAAGATGAAGTGCGTGCTTTAG
GGCTTGAGCTTGGACTTAGCAAAGAAGTGGTTTATCGCCATCCTTTCCCTGGGCCAGGGCTTGCTATACGCATTATGGGA
GAAGTAAATCGCCCTAGCTTAGAACTATTGCGCAAGGCTGATGTAATTTTACTCGAAGAACTTAAAAGTACAGGTTGGTA
TGATAAAACTTGGCAAGCATTTTGCGTGCTTTTAAATATTAAAAGCGTTGGGGTTATGGGGGATAACCGCACTTATGATA
ATGCAGTTTGCATACGCGTTGTAGATGCAAGCGATGGTATGACAGCTACTTTCTCGCATTTACCTTATGAAGTTTTAGAA
AACATAAGTCGCCGTATCATCAATGAAGTAGAAGGTATAAACCGCGTTGTTTATGATATCTCAAGCAAACCACCTGCAAC
CATAGAATGGGAATGA

Protein sequence :
MKKADILVLDFGSQYTQLIARRLREQGVYAEILPFNVSLADIKAKEPKGIILSGGPASVYATDAYFCDKGIFDLGLPILG
ICYGMQLMAHHYKATVAPAGHKEYGKANIEVKKDSALFKNLPKKQTVWMSHSDKVENLPQGFEVLATSENSPFCVFGNED
KKFFALQFHPEVQHSEFGKNILKNFAKYACNCESVWNMGSFAKTQAEKIREEVGSDKVLCAVSGGVDSSVVAALLASAIK
EQVIVVFVDNGLLRSGEKEQVEFMFKNTLGIDLISIDASEIFLSRLANVRDPEQKRKIIGNTFIEVFEEEAKKHKDVKYL
AQGTLYTDIIESSVVGASKTIKSHHNVGGLPEKMNLKLIEPLKEIFKDEVRALGLELGLSKEVVYRHPFPGPGLAIRIMG
EVNRPSLELLRKADVILLEELKSTGWYDKTWQAFCVLLNIKSVGVMGDNRTYDNAVCIRVVDASDGMTATFSHLPYEVLE
NISRRIINEVEGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 5e-136 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 7e-136 55
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 6e-136 55
guaA NP_938969.1 GMP synthase Not tested Not named Protein 1e-116 48