Gene Information

Name : tetA (APECO1_O1R83)
Accession : YP_001481436.1
Strain :
Genome accession: NC_009838
Putative virulence/resistance : Resistance
Product : TetA
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG2814
EC number : -
Position : 89603 - 90793 bp
Length : 1191 bp
Strand : -
Note : tetracycline resistance protein

DNA sequence :
ATGAAATCTAACAATGCGCTCATCGTCATCCTCGGCACCGTCACCCTGGATGCTGTAGGCATAGGCTTGGTTATGCCGGT
ACTGCCGGGCCTCTTGCGGGATATCGTCCATTCCGACAGCATCGCCAGTCACTATGGCGTGCTGCTAGCGCTATATGCGT
TGATGCAATTTCTATGCGCACCCGTTCTCGGAGCACTGTCCGACCGCTTTGGCCGCCGCCCAGTCCTGCTCGCTTCGCTA
CTTGGAGCCACTATCGACTACGCGATCATGGCGACCACACCCGTCCTGTGGATCCTCTACGCCGGACGCATCGTGGCCGG
CATCACCGGCGCCACAGGTGCGGTTGCTGGCGCCTATATCGCCGACATCACCGATGGGGAAGATCGGGCTCGCCACTTCG
GGCTCATGAGCGCTTGTTTCGGCGTGGGTATGGTGGCAGGCCCCGTGGCCGGGGGACTGTTGGGCGCCATCTCCTTGCAT
GCACCATTCCTTGCGGCGGCGGTGCTCAACGGCCTCAACCTACTACTGGGCTGCTTCCTAATGCAGGAGTCGCATAAGGG
AGAGCGTCGACCGATGCCCTTGAGAGCCTTCAACCCAGTCAGCTCCTTCCGGTGGGCGCGGGGCATGACTATCGTCGCCG
CACTTATGACTGTCTTCTTTATCATGCAACTCGTAGGACAGGTGCCGGCAGCGCTCTGGGTCATTTTCGGCGAGGACCGC
TTTCGCTGGAGCGCGACGATGATCGGCCTGTCGCTTGCGGTATTCGGAATCTTGCACGCCCTCGCTCAAGCCTTCGTCAC
TGGTCCCGCCACCAAACGTTTCGGCGAGAAGCAGGCCATTATCGCCGGCATGGCGGCCGACGCGCTGGGCTACGTCTTGC
TGGCGTTCGCGACGCGAGGCTGGATGGCCTTCCCCATTATGATTCTTCTCGCTTCCGGCGGCATCGGGATGCCCGCGTTG
CAGGCCATGCTGTCCAGGCAGGTAGATGACGACCATCAGGGACAGCTTCAAGGATCGCTCGCGGCTCTTACCAGCCTAAC
TTCGATCATTGGACCGCTGATCTTCACGGCGATTTATGCCGCCTCGGCGAGCACATGGAACGGGTTGGCATGGATTGTAG
GCGCCGCCCTATACCTTGTCTGCCTCCCCGCGTTGCGTCGCGGTGCATGGAGCCGGGCCACCTCGACCTGA

Protein sequence :
MKSNNALIVILGTVTLDAVGIGLVMPVLPGLLRDIVHSDSIASHYGVLLALYALMQFLCAPVLGALSDRFGRRPVLLASL
LGATIDYAIMATTPVLWILYAGRIVAGITGATGAVAGAYIADITDGEDRARHFGLMSACFGVGMVAGPVAGGLLGAISLH
APFLAAAVLNGLNLLLGCFLMQESHKGERRPMPLRAFNPVSSFRWARGMTIVAALMTVFFIMQLVGQVPAALWVIFGEDR
FRWSATMIGLSLAVFGILHALAQAFVTGPATKRFGEKQAIIAGMAADALGYVLLAFATRGWMAFPIMILLASGGIGMPAL
QAMLSRQVDDDHQGQLQGSLAALTSLTSIIGPLIFTAIYAASASTWNGLAWIVGAALYLVCLPALRRGAWSRATST

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tetA(A) AGK07027.1 TetA(A) Not tested SGI1 Protein 3e-124 80
tetA(A) AGK07085.1 TetA(A) Not tested SGI1 Protein 3e-124 80
tetA YP_006098396.1 tetracycline resistance protein Not tested Tn2411 Protein 4e-124 80
tetA(A) ACK44537.1 TetA(A) Not tested SGI1 Protein 3e-124 80
tetA CAJ77066.1 Tetracycline resistance protein Not tested AbaR1 Protein 2e-124 80
tetA(A) ACN81011.1 TetA(A) Not tested AbaR5 Protein 3e-124 80
tet(G) AAK02051.1 tetracycline resistance protein Not tested SGI1 Protein 3e-91 61
tetA(G) ABZ01843.1 TetA(G) Not tested SGI2 Protein 3e-91 61
tetA(G) AGK06974.1 TetA(G) Not tested SGI1 Protein 3e-91 61
tetA(G) AGK07104.1 TetA(G) Not tested SGI1 Protein 3e-91 61
tetA CAJ77034.1 Tetracycline resistance protein Not tested AbaR1 Protein 3e-93 60
tet(H) YP_005176248.1 tetracycline efflux protein, class H Not tested ICEPmu1 Protein 1e-64 50
tetA YP_005797160.1 tetracycline resistance protein, class G (TETA(G)) Not tested AbaR4e Protein 5e-67 49
tetA(B) AAL08445.1 tetracycline resistance protein TetA(B) Not tested SRL Protein 2e-67 48
tetB AEA34667.1 tetracycline resistance determinant Not tested Not named Protein 2e-67 48
tetA(B) AEZ06045.1 tetracycline efflux protein Not tested Tn6167 Protein 2e-67 48
BJAB07104_00277 YP_008207742.1 Permeases of the major facilitator superfamily Not tested AbaR25 Protein 4e-67 48
BJAB0868_00281 YP_008211607.1 Permeases of the major facilitator superfamily Not tested AbaR26 Protein 4e-67 48
tetA(B) AEQ20905.1 tetracycline resistance protein Not tested Tn6166 Protein 4e-67 48
ABZJ_00260 YP_005524216.1 Tetracycline resistance protein, class B (TETA(B) ) (Metal-tetracycline/H(+) antiporter) Not tested AbaR22 Protein 4e-67 48
tetA(B) AFH57202.1 tetracycline resistance protein Not tested AbaR4a Protein 3e-67 48

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetA YP_001481436.1 TetA Y19114.gene.p01 Protein 3e-145 99
tetA YP_001481436.1 TetA NC_011586.7045189.p0 Protein 9e-116 81
tetA YP_001481436.1 TetA X75761.gene.p01 Protein 6e-124 80
tetA YP_001481436.1 TetA NC_010410.6002597.p0 Protein 1e-124 80
tetA YP_001481436.1 TetA CP001485.1.gene2821. Protein 1e-124 80
tetA YP_001481436.1 TetA AF534183.gene.p01 Protein 6e-125 79
tetA YP_001481436.1 TetA NC_010410.6002612.p0 Protein 2e-93 60
tetA YP_001481436.1 TetA AF133140.gene.p01 Protein 2e-93 60
tetA YP_001481436.1 TetA AF133139.gene.p01 Protein 1e-94 60
tetA YP_001481436.1 TetA AY264780.2.gene3.p01 Protein 5e-77 54
tetA YP_001481436.1 TetA AF070999.gene.p01 Protein 3e-81 54
tetA YP_001481436.1 TetA Y19116.gene.p01 Protein 8e-73 53
tetA YP_001481436.1 TetA L06940.gene.p01 Protein 6e-74 53
tetA YP_001481436.1 TetA AY743590.gene.p01 Protein 3e-70 50
tetA YP_001481436.1 TetA Y15510.gene.p01 Protein 1e-65 50
tetA YP_001481436.1 TetA AF121000.gene.p01 Protein 4e-64 49
tetA YP_001481436.1 TetA AJ420072.gene.p01 Protein 3e-63 49
tetA YP_001481436.1 TetA V00611.gene.p01 Protein 3e-67 48
tetA YP_001481436.1 TetA AB084246.gene.p01 Protein 1e-67 48
tetA YP_001481436.1 TetA NC_010558.1.6275971. Protein 1e-67 48
tetA YP_001481436.1 TetA CP004022.1.gene2534. Protein 3e-66 48
tetA YP_001481436.1 TetA AF038993.gene.p01 Protein 2e-66 48
tetA YP_001481436.1 TetA AF090987.gene.p01 Protein 1e-63 48
tetA YP_001481436.1 TetA L06798.gene.p01 Protein 1e-62 47
tetA YP_001481436.1 TetA AJ250203.gene.p01 Protein 1e-57 45
tetA YP_001481436.1 TetA NC_011595.7059241.p0 Protein 1e-49 44
tetA YP_001481436.1 TetA NC_011586.7043399.p0 Protein 8e-50 44
tetA YP_001481436.1 TetA NC_010410.6003291.p0 Protein 1e-49 44
tetA YP_001481436.1 TetA NC_009085.4918440.p0 Protein 1e-45 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tetA YP_001481436.1 TetA VFG1036 Protein 1e-67 48