Gene Information

Name : murD (Spro_0759)
Accession : YP_001476993.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : -
Position : 847065 - 848384 bp
Length : 1320 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGGCGGATTATCAGGGTAAAAAAGTAGTCATCATCGGGCTGGGCCTTACCGGCCTGTCCTGTGTTGATTTCTTTATGGC
GCGCGGCGTGACGCCACGCGTTATGGATACCCGCATCTCACCGCCAGGGCTGGACAAGCTGCCTGAAAGCGTTGAGCGTC
ATCTGGGCGATTTGAATCAGGACTGGCTGTTGGCGGCGGATTTGATCGTTGCCAGCCCGGGAATGGCGCTGGCTACCCCG
GCATTAAGCGCCGCTGCGGATGCCGGCGTGGAGATCGTCGGCGACGTCGAGCTGTTCTGCCGCGAAGCGCAGGCACCGAT
CGTGGCCATCACCGGCTCTAATGGCAAAAGCACCGTCACTACCCTGGTGGGTGAGATGGCGAAAGCGGCCGGTTGGGCGG
TGGGCGTTGGCGGCAATATCGGCCTGCCTGCGCTGAGTTTGTTACGTCAGGAGTGCCAACTGTACGTGCTGGAGCTATCA
AGCTTCCAACTGGAAACCACCTTCAGCCTGCATGCGGCCGCGGCGACCATTTTGAACGTCACAGAAGATCACATGGACCG
CTACCCATTTGGCCTGCAGCAGTACCGTGCAGCCAAACTGCGCGTTTATGAAAATGCCGAGGTCTGCGTGGTCAATGCGG
ATGATGCGCTAACCATGCCGGTTCGCGGCGCCGATAAGCGCTGCATCAGTTTCGGTGCCGATGTGGGCGACTACCATTTG
AACCGTCAACTGGGCGAAACCTGGCTGCGGGTGCGTGGCGAGAAAATCCTCAATACCCGCGAGATGAAACTGACCGGCCG
TCACAACTATACCAATGCGCTGGCGGCGTTGGCATTGGCCGATGCGGTCAATATCCCGCGAGCCTCCAGTCTGAAAGCGC
TGACCACCTTTACCGGCCTGGCACATCGCTTCCAACTGGCGTGGGAACATAACGGCGTACGCTGGATTAACGATTCCAAA
GCCACCAACGTCGGCAGTACCGAAGCGGCGTTGAATGGTCTGCAGGTGGACGGCACTCTGCATCTGTTGCTGGGCGGCGA
CGGCAAGTCTGCTGACTTTTCCCCGCTGGCGCAGTATCTGCAGGGCGATAACGTCCGTCTTTACTGTTTTGGTCGTGATG
GCGAACAGCTGGCGCAGCTGCGGCCGGAGGTTGCTACGCTGACCGAGACCATGGAACAGGCGATGCAGGCGATAGCCGGT
CGGGTGCAGTCCGACGATATGGTGTTGCTGTCACCGGCATGCGCCAGCCTGGACCAGTTCCGTAATTTTGAAGTGCGCGG
CGACGAGTTCGCCCGTCTGGCACAGGAGCTCGGCGGATGA

Protein sequence :
MADYQGKKVVIIGLGLTGLSCVDFFMARGVTPRVMDTRISPPGLDKLPESVERHLGDLNQDWLLAADLIVASPGMALATP
ALSAAADAGVEIVGDVELFCREAQAPIVAITGSNGKSTVTTLVGEMAKAAGWAVGVGGNIGLPALSLLRQECQLYVLELS
SFQLETTFSLHAAAATILNVTEDHMDRYPFGLQQYRAAKLRVYENAEVCVVNADDALTMPVRGADKRCISFGADVGDYHL
NRQLGETWLRVRGEKILNTREMKLTGRHNYTNALAALALADAVNIPRASSLKALTTFTGLAHRFQLAWEHNGVRWINDSK
ATNVGSTEAALNGLQVDGTLHLLLGGDGKSADFSPLAQYLQGDNVRLYCFGRDGEQLAQLRPEVATLTETMEQAMQAIAG
RVQSDDMVLLSPACASLDQFRNFEVRGDEFARLAQELGG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-54 42
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-54 42