Gene Information

Name : Spro_4107 (Spro_4107)
Accession : YP_001480330.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 4561072 - 4563111 bp
Length : 2040 bp
Strand : -
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCAACTCTACCTGTGCGAGAAACCCAGCCAGGGTAAAGATATCGGCGCTATTCTCGGGGCGACGCAGCGTAAGCAGGG
TTACCTGGCGGGCGCCGGCGTCATTGTCACCTGGGCTATCGGTCACCTGCTGGAACAGGCCCAGCCGGAGACTTACGGTG
AGCAGTTCGGCAGTCCCTGGCGTGAGTCCGTTCTTCCTATCGTCCCTACCCAGTGGAAAATGACGGTCAAAAAAGAGACT
GCCGATCAGTTTGCTGTCATCCGCGGGTTGCTCAAACAGGTTGATTCTGTGGTGATTGCGACCGATGCAGACCGCGAGGG
GGAGGTGATCGCGAGAGAGTTACTGGAGCATTGCCACTTTACCGGCCCGGTCCAGCGCCTCTGGTTGTCAGCGCTGGACG
AGGCCAGTATTCGGCACGCCCTGGCGAACAAGCTCCCAGGCGAGAAGACTGCGCCCCTGTATGAAGCTGGCCTGGCGCGA
TCACGGGCTGACTGGATGACGGGGATGAATTTAACCCGACTTTACACGCTCAAAGCCCGTGAGCAGGGATACGGCGAGGT
GTTATCGATTGGGCGGGTGCAGACCCCTACGCTGGCGCTGGTCGTGAACCGTGACCGCGACATTGCCAACTTCATTTCCA
AACCGTACTGGCAAGTCAGGGCCACGCTGCAGAAGGGCGGGATCGCCTTCCCGGCAAGCTGGGTTCCTGCCGCCAACTAC
TGTGATGAGGAGAAGCGCTGTATTCAACAGAATGTGGCTCAAGCCGTTGTTCAGCTGTGTCAGCAAACAGGTCATGCCGT
TGTGCTTGAGGTGGGGACCGAGCGCAAGAAGGAGTCCGCGCCGTTGGCCTTTGACCTGGGCACCCTGCAGCAGGCTTGCT
CACGCAAGTGGGGGATGAGCGCCAACCAGGCCTTGAGTATCGCGCAGTCTCTGTATGAGACGCACAAAGCCACCACGTAT
CCCCGGACGGATTGCGGCTATCTGCCGACATCGATGCGGGAAGAAGTTGCCGATGTGCTGAGCGCGGTTACCCGCACGGA
CCCAACGCAGAGCGGCAGCGTTGCCAGGCTCGACAGGACATTTGTTTCTCGTATCTGGAATGACAAAAAAATCACGGCGC
ACCACGGGATTATCCCAACCAAACAGCCGTTCGACCTGAGCAAGCTGTCTGCCGACGAGCTTAAGGTTTATCAGCTGATC
CGTCAGCATTACCTGGCGCAGTTCCTGCCGTTACATGAAGTGGATGTGACGGAGGCTACTTTCAATATTGGCGGGCAACT
GTTCCGCACCCGCGGAAAGGTCGAGGTGGTGGCCGGGTGGAAAGTGCTGTTCCAGCATGACGTGAGCGAGGCGAAGGAGG
AATCTACCGACACAGATGATGTCCGGCTGCCAGCCCTGGTTAAAGGTGAAACCGTCGCGGTTGCCGGTGCTGAGCTCAAA
ACGCTGCAAACGAAGCCCCCAGGGCATTTCACCGACGGGACATTGATCGCCGCGATGAAAAATGCAGCGGCATTCGTCAG
TGATCCGCAACTGAAAAAGGTGTTGAAAGAGAACGCGGGGCTGGGGACGGAAGCGACGCGTGCCGGTATCCTGGAGACGC
TGTTTAAACGTGGGTACCTGGAGAAGAAGGGCAAATACCTGCTCTCTACGCCGATCGCCGGCGAACTGATAGATGCGTTA
CCGACCGCACTGACCAACCCCGGGATGACGGCGCTGTGGGAGCAGGCGTTGGACGAGATTGCTCAGGGTCAGATGACACT
CGACACATTCATGAGCCGTCAGGCGCAGTGGACAGGGCACCTGGTGGAGAAAGGAAAGGCGCAAGCCGTGAAGTTTACCG
CGCCACCTTCTCCACCTTGCCCGACCTGTAGCGGCACGATGCGCCGGCGTGCCGGCAAGAAAGGCAGTGGCGCCTTCTGG
GGCTGCAGTAATTACCCCACTTGCCAGGGCATCATTAACATCGATGCTAAAGGTGGGCGCAAGGCTAAGCGCTATAAAGC
AAAATCACCGGCTAAAAATAAAACAACCAAATCAGAGTAA

Protein sequence :
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMTVKKET
ADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLAR
SRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDIANFISKPYWQVRATLQKGGIAFPASWVPAANY
CDEEKRCIQQNVAQAVVQLCQQTGHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQALSIAQSLYETHKATTY
PRTDCGYLPTSMREEVADVLSAVTRTDPTQSGSVARLDRTFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLI
RQHYLAQFLPLHEVDVTEATFNIGGQLFRTRGKVEVVAGWKVLFQHDVSEAKEESTDTDDVRLPALVKGETVAVAGAELK
TLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILETLFKRGYLEKKGKYLLSTPIAGELIDAL
PTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKAQAVKFTAPPSPPCPTCSGTMRRRAGKKGSGAFW
GCSNYPTCQGIINIDAKGGRKAKRYKAKSPAKNKTTKSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 66
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 66
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 66
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 59
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 3e-167 54
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 5e-170 53
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 1e-160 52
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-157 51
topB AAW83109.1 TopB Not tested GGI Protein 1e-123 42