Gene Information

Name : lysS (Spro_3888)
Accession : YP_001480112.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : -
Position : 4307579 - 4309096 bp
Length : 1518 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGTCTGAGCAACAACCACAAGGCGCCGAACAGGCGCTGGATCTCAATAACGAGTTGCAGTCACGCCGTGAAAAACTGGC
TGCGCTGCGCGAGAACGGCATTGCGTTCCCGAATGATTTCCGTCGCGACACCACGTCCGACAAGCTGCACGCTGCGTACG
GCGATAAAGACAACGAAGAGCTGGAAGCACTGGGTGTAGAAGTCACCGTTGCCGGCCGTATGATGACCCGTCGTATCATG
GGCAAGGCATCCTTTGTCACGCTGCAAGACGTTGGTGGCCGCATCCAGTTGTACGTCGCCCGCGACGATCTGGCGGAAGG
CGTTTACAACGAAGAATTCAAGAAGTGGGACCTGGGTGACATCCTTGGCGCACGCGGTAAGCTGTTCAAAACCAAGACCG
GCGAGCTGTCTATCCACTGCACCGAACTGCGCCTGCTGACCAAGGCCCTGCGCCCGCTGCCGGACAAGTTCCACGGCCTG
GCCGATCAGGAAACCCGCTATCGTCAGCGTTACCTGGATCTGATTGCCAACGACGAATCGCGCAAGACCTTCCAGGTGCG
TTCTCAGATCATGGCGGCGATGCGTAACTTCATGGTGGAACGCGGCTTCATGGAAGTCGAAACCCCTATGATGCAGGTGA
TCCCGGGTGGTGCTTCTGCTCGTCCATTCGTGACTCACCACAATGCGCTGGACATCGATATGTATCTGCGTATTGCCCCA
GAGCTGTACCTGAAGCGTCTGGTGGTAGGTGGCTTCGAGCGCGTGTTCGAAATCAACCGTAACTTCCGTAACGAAGGCGT
TTCTCCGCGTCATAACCCAGAGTTCACCATGATGGAACTCTATATGGCTTACGCGGATTACAAAGATCTGATCGAACTGA
CCGAGTCGCTGTTCCGCACCCTGACCCAGAACGTGCTGGGTAATACTCAGGTGCAGTACGGTGATGAAGTGTTCGACTTC
GGCAAGCCGTTCGTGAAGCTGACCATGACCGAGGCGATCAAAAAATACCGTCCGGAAACCGATCTGGCTGACCTGGCTGA
TATGGGTAAAGCGGTGGCTATCGCTGAATCCATCGGCATCAAGGTTGAGAAGAGCTGGGGTCTGGGCCGCGTAGTGACCG
AGATCTTCGAAGAAGTGGCGGAAAGCCATCTGATTCAGCCGACTTTCATCACTGAATACCCGGCCGAAGTTTCACCGCTG
GCGCGCCGTAACGACGTTAACCCGGAAATCACTGACCGCTTTGAGTTCTTCATCGGCGGCCGTGAAATCGGCAACGGCTT
CTCCGAGCTGAATGACGCAGAAGACCAGGCGCAGCGTTTTGCTGACCAGGCTAATGCGAAAGACGCAGGTGATGACGAAG
CCATGTTCTACGACGAAGACTACGTCACCGCGCTGGAGCACGGCCTGCCACCAACCGCAGGTCTGGGCATCGGTATCGAC
CGTATGGTGATGCTGTTCACTAACAGCCACACCATTCGCGACGTGATTCTGTTCCCGGCAATGCGCCCACAGAAATAA

Protein sequence :
MSEQQPQGAEQALDLNNELQSRREKLAALRENGIAFPNDFRRDTTSDKLHAAYGDKDNEELEALGVEVTVAGRMMTRRIM
GKASFVTLQDVGGRIQLYVARDDLAEGVYNEEFKKWDLGDILGARGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
ADQETRYRQRYLDLIANDESRKTFQVRSQIMAAMRNFMVERGFMEVETPMMQVIPGGASARPFVTHHNALDIDMYLRIAP
ELYLKRLVVGGFERVFEINRNFRNEGVSPRHNPEFTMMELYMAYADYKDLIELTESLFRTLTQNVLGNTQVQYGDEVFDF
GKPFVKLTMTEAIKKYRPETDLADLADMGKAVAIAESIGIKVEKSWGLGRVVTEIFEEVAESHLIQPTFITEYPAEVSPL
ARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFADQANAKDAGDDEAMFYDEDYVTALEHGLPPTAGLGIGID
RMVMLFTNSHTIRDVILFPAMRPQK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 9e-170 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001480112.1 lysyl-tRNA synthetase VFG1668 Protein 5e-170 69