Gene Information

Name : thyA (Spro_3821)
Accession : YP_001480045.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : 2.1.1.45
Position : 4228016 - 4228810 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATCTGGATTTGATGAACAAAGTGCTCGCCGAGGGCACCCCTAAAGCCGACCGTACCGGCACTGGCACCTT
GTCGATATTCGGCCACCAGATGCGTTTCAATTTGCAGGAAGGGTTTCCGCTGGTCACTACCAAAAAGTGTCACCTGCGTT
CAATCATCCATGAGCTGCTGTGGTTCCTGAACGGTGACACCAACGTGGCTTACCTGAAGGAAAACAAAGTCAGCATCTGG
GACGAGTGGGCCGATGAAAACGGTAACCTTGGCCCGGTGTACGGCAAGCAGTGGCGTGCCTGGGGGACGGCGGACGGTCG
TCAGATCGATCAATTGACCACCGTGCTGAACCAGTTGAAACAGGACCCGGATTCACGCCGTATCATTGTTTCAGCCTGGA
ACGTGGGGGAGTTGGATCAGATGGCGTTGGCACCGTGCCACGCGTTCTTCCAGTTCTACGTGGCGGATGGCAAATTGTCT
TGCCAACTGTACCAGCGTTCCTGCGATGTGTTCCTCGGTTTGCCGTTCAACATTGCCAGCTACGCGCTATTGGTACATAT
GATGGCGCAGCAATGTGACCTGGAAGTGGGTGATTTCGTCTGGACCGGCGGCGACACTCATTTGTACAGCAACCATATGG
AACAAACCCAGCTGCAGTTGACGCGTGAGCCGCGTGCCTTGCCGAAATTGGTGATCAAGCGCAAGCCGGCATCGCTGTTT
GATTACCGTTTCGAAGACTTTGAAATCGAAGGTTACGATCCGCACCCAGCCATTAAGGCACCGGTTGCCATCTGA

Protein sequence :
MKQYLDLMNKVLAEGTPKADRTGTGTLSIFGHQMRFNLQEGFPLVTTKKCHLRSIIHELLWFLNGDTNVAYLKENKVSIW
DEWADENGNLGPVYGKQWRAWGTADGRQIDQLTTVLNQLKQDPDSRRIIVSAWNVGELDQMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMEQTQLQLTREPRALPKLVIKRKPASLF
DYRFEDFEIEGYDPHPAIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 2e-87 66