Gene Information

Name : cadB (Spro_3768)
Accession : YP_001479992.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Virulence
Product : lysine/cadaverine antiporter
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0531
EC number : -
Position : 4163917 - 4165266 bp
Length : 1350 bp
Strand : -
Note : antiporter protein responsible for lysine import and cadaverine export; member of the lysine-dependent acid resistance system 4 (AR4); inner membrane protein

DNA sequence :
ATGGGTTCATCCAAGAAAATAGGGCTTATTGCCTGCACCGGTGTGGTTGCCGGTAATATGATGGGGAGCGGTATTGCCTT
ATTACCCGCGAACCTGGCAAGCCTCGGTTCTATCGCCATCTGGGGATGGGTAATCTCTATTATTGGCGCGATGTCACTGG
CTTATGTCTATGCGCGTCTGGCCACCAAAAACCCTCAGCAGGGTGGCCCTATTGCTTACGCGGGTGAAATTTCCCCGGCG
TTTGGTTTCCAGACCGGTGTGCTTTATTACCATGCGAACTGGATCGGTAATTTGGCCATCGGCATTACCGCAGTTTCTTA
TCTCTCTACCTTCTTCCCTGCATTGAATAATCCGGTACCGGCAGGTATTGCCTGTATCGCCATCGTCTGGATATTCACCT
TTGTTAACCTGCTTGGCGGGACCTGGGTCAGCCGCTTGACCACCCTCGGCCTGGTGCTGGTGCTGATCCCGGTGATTGTC
ACCGCGACTGCGGGCTGGCATTGGTTCGACGCTGCAACCTACCACGCTAACTGGAACACTTCCGGTACCACCGACAGCCA
TGCGGTAATCAAAAGTATTCTGCTGTGCCTGTGGGCGTTCATCGGCGTAGAGTCTGCCGCCGTGAGCACCGGCATGGTGA
AAAACCCGAAACGCACCGTACCGCTGGCAACCATGCTGGGTACCGCGCTGGCCGGGATTATCTACATTGCGGCCACTCAG
GTGATGAGCGGTATGTTCCCGGCTAGCCAAATGGCTGCCAGCGGTGCACCGTTCGCCGTCAGCGCCTCCGCCATTATGGG
TAACTGGGCTGCACCACTGGTCTCTGCCTTCACCGCCTTTGCCTGCCTGACTTCACTGGGTTCGTGGATGATGCTGGTTG
GCCAGGCCGGGGTTCGTGCCGCCAACGACGGTAACTTCCCGAAAGTTTATGGTGAAGTCGATAAAAACGGCGTGCCGAAA
AAAGGCCTGCTGCTGGCAAGCTGCAAAATGACCGCGCTGATGGTGCTGATTACCGCCATGAGCTCCGGCGGCGGTAAAGC
TTCCGACCTGTTCGGCATGCTGACCGGTATTGCGGTGCTGCTGACCATGTTGCCTTACTTCTACTCTTGCGTAGACCTGA
TCCGCTTCGAAGGCGTCAATATCCGTAACCTGTTGAGCCTGATTGCCTCGGTTCTGGGTTGTGGCTTCTGCTTCATCGCA
CTGATGGGGGCCGAATCGTTCGAACTGGCCGGTACCTTCATCATCAGCCTGATCATCCTGATGTTCTACGCCCGCAAAAT
GAATACCCGTCAGACAGCGAAAGCCAATGCTGTAGCCATCGACGACAGCTCGACGGCCAAAGCGCACTAA

Protein sequence :
MGSSKKIGLIACTGVVAGNMMGSGIALLPANLASLGSIAIWGWVISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPA
FGFQTGVLYYHANWIGNLAIGITAVSYLSTFFPALNNPVPAGIACIAIVWIFTFVNLLGGTWVSRLTTLGLVLVLIPVIV
TATAGWHWFDAATYHANWNTSGTTDSHAVIKSILLCLWAFIGVESAAVSTGMVKNPKRTVPLATMLGTALAGIIYIAATQ
VMSGMFPASQMAASGAPFAVSASAIMGNWAAPLVSAFTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDKNGVPK
KGLLLASCKMTALMVLITAMSSGGGKASDLFGMLTGIAVLLTMLPYFYSCVDLIRFEGVNIRNLLSLIASVLGCGFCFIA
LMGAESFELAGTFIISLIILMFYARKMNTRQTAKANAVAIDDSSTAKAH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadB NP_756989.1 lysine/cadaverine antiporter Not tested PAI II CFT073 Protein 4e-167 87
cadB AAL67382.1 cadaverine/lysine antiporter Not tested PAI II CFT073 Protein 3e-167 87
unnamed CAD66196.1 putative lysin/cadaverin transporter Virulence PAI III 536 Protein 3e-137 69

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
cadB YP_001479992.1 lysine/cadaverine antiporter VFG1671 Protein 2e-137 69