Gene Information

Name : guaA (Spro_3595)
Accession : YP_001479819.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : -
Position : 3970951 - 3972528 bp
Length : 1578 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGACAAAAAATATCCATAAGCATCGCATCCTGATTCTGGACTTTGGTTCGCAATACACTCAACTGGTAGCACGCCGCGT
GCGCGAAATCGGCGTTTACTGTGAGCTGTGGGCCTGGGACGTTAGCGAAGAGCAAATCCGCGAATTCAATCCAAGCGGCA
TCATCCTGTCCGGCGGCCCGGAAAGCACCACCGAAGCCAACAGCCCGCGCGCGCCAGAATACGTGTTCACCGCCGGTGTC
CCGGTGCTGGGCGTATGCTACGGCATGCAGACCATGGCGATGCAGTTGGGTGGCCAGGTAGAAGGTTCCAACGAGCGTGA
GTTCGGTTATGCCCAGGTGGAAATCACCACCGAAAGCGCATTGGTGCGCGACATCGAAGACGCACTGAGCCCGGCCGGCA
AACCGCTGCTGGACGTGTGGATGAGCCACGGCGACAAAGTGACCGCTATCCCGGCTGACTTCGTGACCGTTGCCAGCACC
GATACCTGCCCGTTTGCCATTATGGCCAACGAAGAAAAACGCTTCTACGGCGTGCAGTTCCACCCGGAAGTAACCCACAC
CCGTCAGGGCCAGCGTATGCTGGAGCGTTTCGTGCTGGATATCTGCCAGTGTGAAGCCCTGTGGACCCCGGCAACCATCA
TTGAAGATGCGGTAGAACGTATTCGTCAGCAGGTAGGTGAAGATCACGTAATCCTCGGCCTGTCCGGCGGCGTGGATTCT
TCCGTTACCGCGATGCTGCTGCACCGTGCCATCGGTAAACGCCTGACCTGCGTGTTTGTCGACAACGGCCTGTTGCGCCT
GAATGAAGCCGAACAGGTACTGGAAATGTTTGGTGACCACTTCGGCCTGAACATCGTTCACGTGGCGGCAGAAGATCGCT
TCCTGAGCGCCCTGGCCGGTGTTGACGAGCCGGAAGCCAAGCGCAAAATCATTGGTCGCGTGTTCGTTGAGCTGTTCGAC
GAAGAAGCCTGCAAGCAATCTGAAGTTAAATGGCTGGCGCAGGGCACCATCTACCCGGACGTGATCGAATCCGCCGCTTC
TGCCACCGGCAAAGCGCACGTGATCAAGTCGCACCACAACGTGGGTGGCCTGCCGAAAGAGATGAAGCTGGGCCTGGTCG
AACCGCTGAAAGAGCTGTTCAAAGACGAAGTGCGCAAAATTGGCCTGGAACTGGGCCTGCCGTACGACATGCTGTTCCGC
CACCCGTTCCCGGGGCCAGGTCTGGGTGTGCGCGTGCTGGGCGAAGTGAAGAAAGAGTATTGCGACCTGCTGCGTCGCGC
CGATGCCATCTTCATTGAAGAACTGCACAAGGCCGATCTGTACAACAAGGTCAGCCAGGCATTCACCGTGTTCCTGCCGG
TACGTTCCGTTGGCGTGATGGGCGATGGCCGTAAATACGACTGGGTTGTTTCACTGCGCGCAGTGGAAACCATCGACTTT
ATGACCGCGCATTGGGCGCACCTGCCGTACGATTTCCTCGGCCGCGTCTCCAACCGCATCATCAACGAAGTGAACGGCAT
TTCCCGTGTAGTTTATGACATCAGCGGCAAGCCACCGGCTACCATTGAATGGGAATGA

Protein sequence :
MTKNIHKHRILILDFGSQYTQLVARRVREIGVYCELWAWDVSEEQIREFNPSGIILSGGPESTTEANSPRAPEYVFTAGV
PVLGVCYGMQTMAMQLGGQVEGSNEREFGYAQVEITTESALVRDIEDALSPAGKPLLDVWMSHGDKVTAIPADFVTVAST
DTCPFAIMANEEKRFYGVQFHPEVTHTRQGQRMLERFVLDICQCEALWTPATIIEDAVERIRQQVGEDHVILGLSGGVDS
SVTAMLLHRAIGKRLTCVFVDNGLLRLNEAEQVLEMFGDHFGLNIVHVAAEDRFLSALAGVDEPEAKRKIIGRVFVELFD
EEACKQSEVKWLAQGTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKLGLVEPLKELFKDEVRKIGLELGLPYDMLFR
HPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELHKADLYNKVSQAFTVFLPVRSVGVMGDGRKYDWVVSLRAVETIDF
MTAHWAHLPYDFLGRVSNRIINEVNGISRVVYDISGKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-127 50
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-127 50
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 1e-127 50
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-111 48