Gene Information

Name : Spro_0310 (Spro_0310)
Accession : YP_001476548.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : 5.99.1.2
Position : 364529 - 366568 bp
Length : 2040 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCAACTCTACCTGTGCGAAAAACCCAGTCAGGGTAAAGATATCGGCGCCATTCTCGGGGCGACGCAGCGAAAACAGGG
TTACCTGGCGGGCGCTGGCGTGATAGTCACCTGGGCTATAGGGCATCTGCTGGAACAGGCCCAGCCGGAGACCTACGGTG
AGCAGTTCGGCAGTCCCTGGCGGGAGTCCGTTCTTCCTATTGTCCCTACCCAGTGGAAAATGGCGGTAAAAAAAGACACT
GCCGACCAGTTCGCTGTTATCCGCGGGTTGCTCAAACAGGTTGATTCTGTGGTGATTGCGACCGATGCGGATCGCGAGGG
GGAAGTGATCGCGCGGGAGTTACTGGAACATTGCCACTTTACCGGCCCGGTCCAGCGGCTCTGGTTGTCAGCGCTGGACG
AGGCCAGTATTCGGCATGCCCTGGCGAACAAACTCCCTGGCGAGAAGACCGCGCCCCTGTATGAAGCTGGCCTGGCGCGA
TCACGTGCTGACTGGATGACGGGGATGAATTTAACCCGGCTTTATACGCTCAAAGCCCGTGAGCAGGGATACGGCGAGGT
ATTGTCGATCGGGCGGGTGCAGACCCCCACGCTGGCGCTGGTCGTGAACCGAGACCGCGACATTACCAACTTCATCTCCA
AACCGTACTGGCAAGTCAGGGCCACGCTGCAAAAAGGCGGGATCACTTTCCCGGCAAACTGGGTACCAGCCGCCAACTAC
TGTGATGAAGAGAAGCGCTGTATTCAACAGAATGTGGCGCAGGCCGTCGTGCAGCGGTGTCAGCAAACGGCTCATGCCGT
TGTGCTTGAGGTGGGGACCGAGCGCAAGAAAGAGTCCGCGCCGTTGGCATTTGATCTGGGCACCCTGCAGCAGGCTTGCT
CCCGCAAGTGGGGGATGAGCGCCAACCAGGTCTTGAGTATCGCACAGTCACTGTATGAGACGCACAAGGCCACCACATAT
CCCCGGACGGATTGCGGCTATCTGCCGACATCGATGCGGGAAGAGGTTGCCGATGTGCTGAGCGCTGTTACCCGCACGGA
CCCAACGCTCAACGAAAGCGTGGCCAGGCTCGACAGGGCTTTTGTTTCCCGTATCTGGAATGACAAAAAAATTACGGCGC
ACCACGGGATTATCCCAACCAAACAGCCGTTCGACCTGAGCAAGTTGTCAGCCGATGAGCTCAAGGTCTATCAGCTGATC
CGTCAGCATTACCTGGCACAGTACCTGTCCTTACATGAAGTAGATGTGACGGAAGCCACCTTCAATATCGGCGGGCAACT
GTTCCGCACCCGCGGCAAGGTCGAGGCTGTTGCTGGATGGAAAGTGTTGTTCCAGCATGACGTGAGCGAGGCGAAAGAGG
AACCGGCTGACACGGATGATGTCCGGCTGCCGGCGCTGGTTAAAGGGGAAACCGTCGCGGTAGCCGGCGCTGAGCTCAAA
ACGTTGCAGACGAAGCCCCCAGGACATTTCACCGACGGGACACTGATCGCCGCCATGAAAAATGCAGCGGCGTTCGTCAG
TGACCCGCAACTGAAGAAAGTGTTGAAAGAGAACGCAGGGCTGGGTACTGAAGCGACGCGCGCCGGTATCCTGGATACGC
TGTTTAAACGCGGGTACCTGGAGAAGAAGGGCAAATACCTACTCTCCACACCGATCGCCGGCGAACTGATTGATGCGTTA
CCGACTGCGCTGACCAACCCCGGGATGACGGCGCTGTGGGAGCAGGCGCTGGACGAGATTGCCCAGGGCCAGATGACACT
CGATACGTTCATGAGCCGCCAGGCACAGTGGACAGGGCATCTGGTGGAGAAAGGGAAGACGCAGGCTGTGAAGTTTACCG
CCCCACCTTCACCGCCGTGCCCGACATGCAGTGGGTCGATGCGCCGGCGTGCCGGCAAGAAAGGCGGTGGTGCTTTCTGG
GGCTGCAGTAATTATCCCACTTGCCAGGGTGTCATTAACATCGATGCAAAAGGTGGGCGCAAGGCTAAGCGCTATAAAGC
GAAATCACCGACTAAAAATAAAGCAACAGGATCGGAGTAA

Protein sequence :
MQLYLCEKPSQGKDIGAILGATQRKQGYLAGAGVIVTWAIGHLLEQAQPETYGEQFGSPWRESVLPIVPTQWKMAVKKDT
ADQFAVIRGLLKQVDSVVIATDADREGEVIARELLEHCHFTGPVQRLWLSALDEASIRHALANKLPGEKTAPLYEAGLAR
SRADWMTGMNLTRLYTLKAREQGYGEVLSIGRVQTPTLALVVNRDRDITNFISKPYWQVRATLQKGGITFPANWVPAANY
CDEEKRCIQQNVAQAVVQRCQQTAHAVVLEVGTERKKESAPLAFDLGTLQQACSRKWGMSANQVLSIAQSLYETHKATTY
PRTDCGYLPTSMREEVADVLSAVTRTDPTLNESVARLDRAFVSRIWNDKKITAHHGIIPTKQPFDLSKLSADELKVYQLI
RQHYLAQYLSLHEVDVTEATFNIGGQLFRTRGKVEAVAGWKVLFQHDVSEAKEEPADTDDVRLPALVKGETVAVAGAELK
TLQTKPPGHFTDGTLIAAMKNAAAFVSDPQLKKVLKENAGLGTEATRAGILDTLFKRGYLEKKGKYLLSTPIAGELIDAL
PTALTNPGMTALWEQALDEIAQGQMTLDTFMSRQAQWTGHLVEKGKTQAVKFTAPPSPPCPTCSGSMRRRAGKKGGGAFW
GCSNYPTCQGVINIDAKGGRKAKRYKAKSPTKNKATGSE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 65
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 65
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 65
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 59
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-164 53
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 5e-166 52
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 2e-156 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-154 50
topB AAW83109.1 TopB Not tested GGI Protein 7e-122 43