Gene Information

Name : tpx (Spro_2616)
Accession : YP_001478845.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Virulence
Product : thiol peroxidase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG2077
EC number : -
Position : 2879603 - 2880106 bp
Length : 504 bp
Strand : +
Note : antioxidant activity; thioredoxin-dependent thiol peroxidase; forms homodimers in solution; shows substrate specificity to alkyl hydroperoxides; periplasmic protein

DNA sequence :
ATGACTCAGACAGTACATTTTCAAGGCAACCCGGTTAGCGTTGCAGGCCACCTGCCACAAACCGGCGAACAAGCCAAAAC
CTTCTCACTGGTTGCCAAAGACTTGTCGGACGTGGCGCTGAGCAGCTTCGCGGGGAAACGCAAAGTTCTGAACATTTTCC
CAAGTATTGATACCGGCGTTTGCGCAACTTCGGTTCGTACATTCAACCAGTTGGCCAGCGGCCTGGATAACACCGTGGTG
CTGTGCATCTCGGCCGACCTGCCGTTCGCCCAGTCACGTTTCTGCGGTGCAGAAGGCCTGAACAATGTAGTCACCCTGTC
CACGCTGCGTGGCGCAGAATTCAAACAGGCTTACGGCGTTGAAATCGCTGAAGGCCCGCTGGCAGGCCTGACCGCACGTG
CGGTTGTGGTATTGGATGGCCAGGACAACGTGCTGTACAGCGAGCTGGTGAATGAAATTACCACCGAGCCTAACTACGAT
GCGGCGCTGGCTGCATTGAAGTAA

Protein sequence :
MTQTVHFQGNPVSVAGHLPQTGEQAKTFSLVAKDLSDVALSSFAGKRKVLNIFPSIDTGVCATSVRTFNQLASGLDNTVV
LCISADLPFAQSRFCGAEGLNNVVTLSTLRGAEFKQAYGVEIAEGPLAGLTARAVVVLDGQDNVLYSELVNEITTEPNYD
AALAALK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tpx YP_001216305.1 thiol peroxidase Not tested VPI-1 Protein 1e-34 48
tpx NP_230472.1 thiol peroxidase Virulence VPI-1 Protein 5e-35 48
tagD AAK20751.1 toxR-activated gene D protein Virulence VPI Protein 7e-35 48
tagD AAK20781.1 toxR-activated gene D protein Virulence VPI Protein 3e-35 48

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
tpx YP_001478845.1 thiol peroxidase VFG0087 Protein 1e-35 48