Gene Information

Name : hemC (Spro_0178)
Accession : YP_001476416.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 201395 - 202336 bp
Length : 942 bp
Strand : -
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGTTAGACAAAATTATTCGAATTGCCACCCGACAAAGCCCACTCGCTCTCTGGCAGGCACATTATGTGCAGCAGCGCCT
GATGGCCAACCACCCTGGCCTGCAGGTTGAACTGGTGCCAATGGTCACTAAGGGCGACATTATTCTGGATACGCCACTGG
CGAAGGTCGGTGGTAAAGGGCTGTTTGTTAAGGAACTTGAGCTGGCGTTACTCGATGGCCGTGCCGATATCGCCGTCCAT
TCGATGAAAGACGTCCCGGTAGATTTCCCCGCCGGCCTGGGTTTGGTGACCATTTGCGAGCGCGACGATCCACGCGACGC
ATTTGTATCCAATCGTTTCACCTCGCTCGATCAACTGCCGCAGGGCAGCGTGGTTGGCACCTCCAGCCTGCGCCGCCAGT
GCCAGTTACGTGAGCGTCGTCCGGACCTGATCGTGCGCGATCTGCGCGGCAACGTTGGCACCCGTTTGTCAAAACTGGAC
AACGGTGATTACGACGCCATTATTCTGGCGGTCGCCGGGCTCAAGCGCCTGGGTCTGGAACAGCGCATCCGCAGCCCGCT
TAGCCCGGAAGAGTGCTTGCCGGCGGTCGGTCAGGGTGCTGTGGGCATTGAGTGCCGCCTCGACGATGAAACCACCCGTG
CGCTACTGGCCCCGCTCAATCATGCCGTCACCGAAACCCGCGTTCGTGCCGAACGTGCGATGAATACCCGGTTGGAAGGC
GGTTGTCAGGTGCCGATCGGCAGCTATGCCGAACTCGATGGCGACAGCCTGTGGCTGCGTGCATTGGTAGGCTCCCCGGA
CGGCAGTCAGATGGTGCGCGGCGAACGTCGCGGCCCGGCAGCGCTGGCGGAACAAATGGGCATTGAGCTGGCGGAAGAGT
TGCTGGCGCAGGGCGCACGCGAAATTCTACAGGATGTTTATCAGGGAAATCCTCCGGCATGA

Protein sequence :
MLDKIIRIATRQSPLALWQAHYVQQRLMANHPGLQVELVPMVTKGDIILDTPLAKVGGKGLFVKELELALLDGRADIAVH
SMKDVPVDFPAGLGLVTICERDDPRDAFVSNRFTSLDQLPQGSVVGTSSLRRQCQLRERRPDLIVRDLRGNVGTRLSKLD
NGDYDAIILAVAGLKRLGLEQRIRSPLSPEECLPAVGQGAVGIECRLDDETTRALLAPLNHAVTETRVRAERAMNTRLEG
GCQVPIGSYAELDGDSLWLRALVGSPDGSQMVRGERRGPAALAEQMGIELAEELLAQGAREILQDVYQGNPPA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 4e-85 62
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 4e-85 62