Gene Information

Name : Spro_1719 (Spro_1719)
Accession : YP_001477951.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1888244 - 1888993 bp
Length : 750 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTATCGCAATTATTCCAGCCCGTTATGCATCAACCCGTTTACCGGGTAAACCGCTGGCCGATATCCACGGCAA
GCCGATGGTGGTGCATGTTATGGAACGTGCACGCGAGTCGGGCGCCAGCCGCGTTATTGTCGCGACCGATCACCCGGCAG
TAGCCGAAGCGGTCAAAGCGGCAGGCGGTGAAGTCTGCATGACCCGGGCCGATCACAATTCCGGCACCGAGCGCTTGGCA
GAGGTGATCGAGCATTATGGGTTCGCTGATGACGAAATCATCGTTAACGTTCAGGGTGATGAGCCACTGATCCCACCGGT
GATTGTGCGTCAGGTGGCTGAAAATCTGGCGGGCAGTCAGGCCGGAATGGCTACCCTGGCGGTGCCTATCGAAAGCGCAG
AAGAAGCTTTTAACCCCAATGCGGTCAAAGTGGTGATGGATGCACAGGGTTATGCGCTCTATTTCTCACGCGCCACCATT
CCATGGGATCGCGAACGCTTTGCCCAATCCAAAGAAAGCATCGGCGACAGCCTGTTGCGCCACATAGGTATTTACGCCTA
TCGCGCCGGTTTTGTTCGCCGTTACGTTACCTGGGCGCCAAGCCAGCTGGAGCAAATTGAGCTGCTGGAACAGTTGCGGG
TGCTGTGGTACGGCGAAAAAATCCACGTGGCGGTTGCCAAGGCAATGCCGACCGTGGGTGTCGATACGCAGGAAGATTTG
CAGCGCGTGCGCGACAGTATCAAAGGCTGA

Protein sequence :
MSFIAIIPARYASTRLPGKPLADIHGKPMVVHVMERARESGASRVIVATDHPAVAEAVKAAGGEVCMTRADHNSGTERLA
EVIEHYGFADDEIIVNVQGDEPLIPPVIVRQVAENLAGSQAGMATLAVPIESAEEAFNPNAVKVVMDAQGYALYFSRATI
PWDRERFAQSKESIGDSLLRHIGIYAYRAGFVRRYVTWAPSQLEQIELLEQLRVLWYGEKIHVAVAKAMPTVGVDTQEDL
QRVRDSIKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-28 46
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 8e-28 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 6e-28 45