Gene Information

Name : Spro_1626 (Spro_1626)
Accession : YP_001477858.1
Strain : Serratia proteamaculans 568
Genome accession: NC_009832
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 2.5.1.48
Position : 1780703 - 1781848 bp
Length : 1146 bp
Strand : -
Note : PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent protein; aromatic amino acid beta-eliminating lyase/threonine aldolase; KEGG: yen:YE1469 putative cystathionine gamma-synthase

DNA sequence :
ATGGCCAAGTTTGATACGTTGACCGTTCACGCCGGTTATACCCCGGACGCTACCGGCGCAGTGATGCCGGCCATTTATGC
CACCTCCACCTATGCCCAACCGGCACCGGGGGAACATACCGGCTATGAATATTCGCGCAGCGCCAACCCAACACGCACTG
CGTTGGAGAGCGCCATCGCCGAACTGGAAAGCGGCAGCCGCGGCTACGCTTTCGCTTCTGGTCTGGCGGCCTGCTCGACG
GTGCTGGAGCTGCTCGATCAGGGCAGCCACCTGGTGGCGGTTGACGATCTGTACGGCGGGACCTATCGCCTGCTGGAAAA
GGTGCGTAGCCGCACCGCCGGATTGCGGGTTACCTATGTTTCCCCGGCGGACATTACCGCACTGGAGCAGGCGATCGAAC
CGGATACCAAAATGATCTGGGTGGAAACGCCGACCAATCCGCTGTTGAAGCTGGCGGACTTGAGTGCGATCGCGGCGATC
GCCAAAAAACACGATTTAATCAGCGTGGCGGACAACACCTTCGCCTCACCTTATATTCAACGTCCGCTGGAACTCGGCTT
TGACGTGGTGGTGCATTCCGCCACCAAATACCTCAATGGCCATTCCGACGTGGTGGCCGGTGTGGCCGCGGTAGGGAATA
ACCCGGAGTTGGCCGAACAGCTAGGTTTCCTGCAAAACGCGGTAGGTGGCATTCTCGATCCGTTCAGCAGCTTCCTGACG
TTGCGCGGTATCCGCACGCTGGCGCTGCGCATGGAGCGTCACAGTAATAGCGCCTTGCGCATCGCCCAGTGGCTGGAAAG
CCAACCGCAGGTGGAAGAAGTCTACTATCCGGGCCTGCCGAGCCATCCACAACACGCGCTGGCGGCCAAGCAGATGAGCA
GTTTCGGCGGCATGATTTCGGTGCGCCTGAAAGGTGACGATGCCTTTGCCCGTCGGGTGATCAAACGTTCAAAACTGTTC
ACCCTGGCAGAAAGCCTGGGCGGCGTGGAAAGCCTGATTAGCCAGCCGTTTAGCATGACTCATGCGTCGATCCCGCTGGA
ACAGCGGCTGAAAACCGGCATCACGCCACAGTTACTGCGTCTGTCGGTAGGTATTGAGGATGCGGATGATCTGATCGCCG
ATTTGCAGCAGGCGCTGGCGGAGTAA

Protein sequence :
MAKFDTLTVHAGYTPDATGAVMPAIYATSTYAQPAPGEHTGYEYSRSANPTRTALESAIAELESGSRGYAFASGLAACST
VLELLDQGSHLVAVDDLYGGTYRLLEKVRSRTAGLRVTYVSPADITALEQAIEPDTKMIWVETPTNPLLKLADLSAIAAI
AKKHDLISVADNTFASPYIQRPLELGFDVVVHSATKYLNGHSDVVAGVAAVGNNPELAEQLGFLQNAVGGILDPFSSFLT
LRGIRTLALRMERHSNSALRIAQWLESQPQVEEVYYPGLPSHPQHALAAKQMSSFGGMISVRLKGDDAFARRVIKRSKLF
TLAESLGGVESLISQPFSMTHASIPLEQRLKTGITPQLLRLSVGIEDADDLIADLQQALAE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-79 52
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-80 52
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 4e-49 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Spro_1626 YP_001477858.1 cystathionine gamma-synthase BAC0207 Protein 3e-62 44