Gene Information

Name : Tlet_0789 (Tlet_0789)
Accession : YP_001470419.1
Strain : Thermotoga lettingae TMO
Genome accession: NC_009828
Putative virulence/resistance : Virulence
Product : ATPase
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 803364 - 805811 bp
Length : 2448 bp
Strand : +
Note : PFAM: AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: tma:TM0198 ATP-dependent Clp protease, ATPase subunit

DNA sequence :
ATGTTCGATAGATTTTCTGAAAAATCAGCGCAGGTTTTTGTTGATGCACAAAATGAAGCCAAAGAAATGGGACATTCTTA
TGTTGGAACAGAACATATACTTTTATCGGTTCTGAAACAGGACTTACCTGTTGTTGAAGCTCTTTCTGAGATGGGTATAA
CCTATGCCCGAACAAAAAATGAGGTTATTTCAATGGTGGGCATGGGTATGAGAGGATTTGCCAGTTCACCACAGATGACA
CCGAGGGCAAGAAGAGTAATAGAAATGGCATATGAGGAAGCCAAATATCTTGGAAGTGAGAAAATACATCCAGAACACAT
ACTGCTCGGCATCATAAGAGAAGGTGAAGGAATAGCTGTCCATGTACTCAGGAAAATGGGTATAGATCTTGGTGTATTGA
GGCGCATGATAGTTGAAAGTACTTCACCAAGAATTAACGATGCTGGTAGTGAAAGGACTTTTGAGAATTCGTCGGTGAGA
CATCTGGAAGGTTTTGGTATAGACTTAACGGCGCTTGCGATGAAGAATCAGCTTGACCCGGTTATTGGAAGAGAGGAAGA
AATAGAAAGAGTTATGCAAATTCTGGTGAGAAGGAAGAAAAACAATCCAGTTTTGATTGGGGAGCCCGGAATAGGGAAAA
CGGCTATTGTCGAAGGCCTTGCACAGCGAATCGTTGCTGGAGAGGTTCCTGAGCCGTTGAAACATAAAACAATTTTTTCG
CTCGATGTTGCCGCTCTCGTTGCTGGAACGAAATACAGAGGCGAGTTTGAAAAAAGGATGAAAAAGCTTCTACAGATAGT
TACCAAGGACCCCGGCATAATTTTGTTTATTGACGAAGTCCATACAATAGTTGGTGCAGGATCTGCGGAAGGTGCAGTGG
ATGCAGCAAATATTTTGAAACCAGCCCTTTCTCGTGGAGAGATTCGCTGTATAGGCGCGACAACACCCGATGAATATAGA
AAATACATCGAAAAAGATGCGGCTCTTGAGAGAAGGTTCCAGAAGATCTACGTCAAGGAACCAACTGTCGAAGAGACTAT
TAACATCCTTAAAGGTTTGAGGTACAAATATGAGACTCATCACAGGGTAAAGTATACAGATAATGCGTTAGAGGCTGCCG
TATATTTATCAAAGAGATATATTACAGATCACTTTTTACCCGATAAAGCCATAGATGTAATTGACGAGGCCGCTGCAAGA
GCTCGCTTGAGAAGCTTTGTTATTCCTGATGAGCTGCAACAACTGAGAAAACAGCTTGAGCAAGTCAAAGCCGATAAAGA
ACTTGCCGTTTTAAATCAAGATTATGAAAGAGCAGCAGATCTCAAAGAAAAAGAAAAATTGTTGAATCAGGAGTACACAG
AAAAATATGAGCAATGGAGAAAAAATGTTGAATCTTCAATTGTAGCAGTTGATGTTGATCAGATATCCGAAGTAGTCTCA
GGCTGGACAGGTATTCCTTTGATGAAAATAGAAGAGAACGAGAGCATGAGACTGCTCAATCTTGAGAAAGTTTTACACCA
AAGAATAGTTGGGCAGGATGAAGCAATTAAGGCCATAGCAAGGGCTATAAGAAGGGCGAGAAGCGGGTTGAAAGATCCAA
GAAGGCCCATAGGAGTGTTTCTGTTTCTTGGGCCTACAGGTGTAGGAAAGACCGAACTGACAAAGGTTTTGACCGCGCAT
CTGTTTGGTGACGAGAAAGCTTTACTCAGATTTGACATGAGTGAATATATGGAAAGATTCTCTGTATCCAGATTAATTGG
TGCACCACCTGGTTATGTTGGCTACGAAGAAGGAGGTACTTTAACTGAAAGAGTAAGAAGAAGACCATTTTCAGTTATAC
TCTTTGACGAGATTGAAAAAGCGCATCCTGATGTATTCAATATTTTACTTCAAATTATGGACGATGGCAGGTTGACGGAT
TCGCAGGGAAGAGAAGTGGATTTCAAAAATACCATAGTTGTTATGACAAGTAATATCGGTGGCAATTTGATAAACAAATC
CAAGAAAACTATGGGTTTTGTCTCGCAAGACGCGGATAAAGATTATCAGGAAATGAAATCGTTGGTCCTGGAGGAAGTTA
AGAAAACTTTTAGACCAGAGTTTCTCAACAGGATCGATGAGGTGATAGTTTTCCACCCACTAAACAGGGATCATATAGAA
AAGATCGTTGATATACTTGTATCAGACGTACACAAAAGATTGGAAAGTAAGGGCATGACACTGAAGCTTACGAAGGAAGC
TAAGAATTTCCTGATTGAAAAGGGCTATGATCCTGTATTTGGTGCGAGGCCGTTGAGAAGGGCCATACAACAATACCTCG
AAGATCCGCTGGCAGAAGAATTGCTACGCGGTAAGTTTGCTTTTGGAGATACAGTAGTGTGCAAAGTAAGTGGAAACGGA
TTGAAATTCACCAAACATAGATCTAAAGCGGGAGCACTTAAAGGATGA

Protein sequence :
MFDRFSEKSAQVFVDAQNEAKEMGHSYVGTEHILLSVLKQDLPVVEALSEMGITYARTKNEVISMVGMGMRGFASSPQMT
PRARRVIEMAYEEAKYLGSEKIHPEHILLGIIREGEGIAVHVLRKMGIDLGVLRRMIVESTSPRINDAGSERTFENSSVR
HLEGFGIDLTALAMKNQLDPVIGREEEIERVMQILVRRKKNNPVLIGEPGIGKTAIVEGLAQRIVAGEVPEPLKHKTIFS
LDVAALVAGTKYRGEFEKRMKKLLQIVTKDPGIILFIDEVHTIVGAGSAEGAVDAANILKPALSRGEIRCIGATTPDEYR
KYIEKDAALERRFQKIYVKEPTVEETINILKGLRYKYETHHRVKYTDNALEAAVYLSKRYITDHFLPDKAIDVIDEAAAR
ARLRSFVIPDELQQLRKQLEQVKADKELAVLNQDYERAADLKEKEKLLNQEYTEKYEQWRKNVESSIVAVDVDQISEVVS
GWTGIPLMKIEENESMRLLNLEKVLHQRIVGQDEAIKAIARAIRRARSGLKDPRRPIGVFLFLGPTGVGKTELTKVLTAH
LFGDEKALLRFDMSEYMERFSVSRLIGAPPGYVGYEEGGTLTERVRRRPFSVILFDEIEKAHPDVFNILLQIMDDGRLTD
SQGREVDFKNTIVVMTSNIGGNLINKSKKTMGFVSQDADKDYQEMKSLVLEEVKKTFRPEFLNRIDEVIVFHPLNRDHIE
KIVDILVSDVHKRLESKGMTLKLTKEAKNFLIEKGYDPVFGARPLRRAIQQYLEDPLAEELLRGKFAFGDTVVCKVSGNG
LKFTKHRSKAGALKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 53

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
Tlet_0789 YP_001470419.1 ATPase VFG0079 Protein 0.0 54
Tlet_0789 YP_001470419.1 ATPase VFG0080 Protein 8e-150 51