Gene Information

Name : fliP (Tlet_0627)
Accession : YP_001470257.1
Strain : Thermotoga lettingae TMO
Genome accession: NC_009828
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : 3.1.1.3
Position : 640653 - 641405 bp
Length : 753 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence :
ATGCGGAAGATCCTGATTTTTATTCTTCTGCTTCTACCAGTACTAATTCATCCACAGGAAGAATTGCCTTTTCCATCTAT
TGGCATCGAAATCTCTCCTGTTGGGAATGAACGTGATTTGGTTACGACACTCGAGATCCTTTTAATCATTACTGTTCTCG
CACTTGCTCCAAGTATACTGATACTTTTTACATCTTTCACAAGAATTATAGTCGTATTTTCATTTTTAAGAAATGCCCTT
GGAACAAGGCAAACACCCCCATCCCAAGTGCTTATAGGCCTGGCCCTATTTTTGACATTTTTCATTATGCAACCTGTATG
GAATGACATATATAACGATGCTTTGACCCCATATATGGAAAAAGAAATAGGCTATGAAGAGCTATTCTCGCGAATGATAG
GCCGAGTACGGCAGTTTATGCTGAAAGAACTCGTGGATCATCATAATGAAGATAACGTTTTCTTACTCGCATCGAGTGTG
GGAAAAAAATTTGATAAAATTGAAGATGCGCCAAATTCAATTTTGATACCTGCCTTTGTGCTTGGTGAACTCGAAATAGG
TTTTAAAATGGGAGTGCTTCTGTACATACCTTTTATTGTAATAGACATGATAGTCTCAAGTATATTACTCGCTATGGGAA
TGATAATGATACCGCCTGTACTTATTTCACTCCCTTTTAAGGTGTTACTATTCATAGTTGTAAATGGATGGGATTTGCTT
GTTTCTGGCTTGATAAAAAGTTTCGCGAGGTGA

Protein sequence :
MRKILIFILLLLPVLIHPQEELPFPSIGIEISPVGNERDLVTTLEILLIITVLALAPSILILFTSFTRIIVVFSFLRNAL
GTRQTPPSQVLIGLALFLTFFIMQPVWNDIYNDALTPYMEKEIGYEELFSRMIGRVRQFMLKELVDHHNEDNVFLLASSV
GKKFDKIEDAPNSILIPAFVLGELEIGFKMGVLLYIPFIVIDMIVSSILLAMGMIMIPPVLISLPFKVLLFIVVNGWDLL
VSGLIKSFAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escR AAC38369.1 EscR Virulence LEE Protein 2e-27 42
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 4e-28 42
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 4e-28 42
ssaR CAA68199.1 secretion system apparatus, SsaR Virulence SPI-2 Protein 2e-28 41
ssaR YP_216427.1 type III secretion system protein Virulence SPI-2 Protein 3e-28 41
ssaR NP_460384.1 type III secretion system protein Virulence SPI-2 Protein 3e-28 41
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 1e-27 41
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 1e-27 41
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 1e-27 41
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 1e-27 41
unnamed AAL06354.1 EscR Virulence LEE Protein 8e-29 41
escR AAC31528.1 L0049 Virulence LEE Protein 1e-27 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG2494 Protein 2e-41 47
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG1259 Protein 5e-42 46
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG2338 Protein 1e-39 45
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG2016 Protein 7e-41 44
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG0715 Protein 1e-27 42
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG0519 Protein 1e-28 41
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG0394 Protein 6e-29 41
fliP YP_001470257.1 flagellar biosynthesis protein FliP VFG0827 Protein 6e-28 41