Gene Information

Name : Tlet_0230 (Tlet_0230)
Accession : YP_001469864.1
Strain : Thermotoga lettingae TMO
Genome accession: NC_009828
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 239175 - 240449 bp
Length : 1275 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATAGACATCAGATTAATTCGTGAGAAACCGGATTTTGTGAAAAAAGCACTTGAGAAGCGAAATTACGAGAAAAAAAT
GGTTGATGATCTACTCTCTCTTGATGCACAATTTAGAGAACTCACAAATCAGATTAACCAGCTCCGCGCACAAAGAAATT
CCATCTCAAAGATGGTTGCCCAGGCAAAGTCATCCGGGAAAACAGAGGAGATAGAAAATCTAACTGAAGAAGGAAAAAAG
ATAGGTAGGCAAATAGACTCTATAGAAGATCAATTAAAAGAAATAAAAGTTCAGATGGAAAAATTGATGCTTCTTGTCCC
CAATATCCCAGACGATTCAGTACCCGAGGGAAAAGATGAAACTTCAAACAGAGAAATTCGAAAGTGGGGAGATCCGAAAA
AATTTGATTATAATCCTCAGGCTCACTGGGACCTCGGTCCGTCTCTGGGCCTTATGGATTTCGATCGCGCGGCAAAACTA
AGTGGTTCCAGATTTACTGTTATGTATGGGATGTTTGCAAAACTTGAAAGGGCTCTGACAAATTTTATGCTGGACATGCA
TACAAAAGAGCACGGCTATACAGAAGTCTGGCTCCCCCACATAGTAAAACGAGAAACCATGACCATTACAGGGCAATTAC
CAAAATTCGAAGAAGAGGCTTACAGAATAGAGGCAGATGATCTATTTTTAATACCAACTGCCGAAGTTCCTCTCGTGGCA
CTCAGGTCTAATGAAATTCTTGAAGAAAAAGATCTTCCATTGCTTTATACGGCTTATACACCGTGCTATAGAAGAGAAGC
GGGAAGTTATGGAAAAGATGTACGTGGAATGATCCGTCAACATCAATTTGACAAAGTTGAGCTGGTCTGGATAACCACAC
CGGAAAGATCGTTCGAAGATCTCGAAACGCTTGTTTCCCACGCAGAAGAAGTTCTCAGAAGGCTTGAATTGCCTTACAGA
GTTATTCAATTGTGCAGCGGGGATCTTGGATTTGGTGCGGCCAAAACTTATGATCTTGAAGTCTGGTTACCATCGTATAA
TTCGTACAAAGAGATATCTTCCTGCAGCAACGATACAGATTTTCAGGCTCGAAGAGGCAACATAAGATACCGGAGAAAAG
ACGGAAAAATTTCTTTTGTCCACACATTAAATGGTTCTGGCGTTGCAGTGGGCAGAACCTTAGTAGCAATAATAGAAAAT
TATCAAAGGGCCGACGGCAGGATAGATGTACCAAAAGCACTGCAACCGTACCTTGGCTGTGAGGTGCTGGGATAA

Protein sequence :
MIDIRLIREKPDFVKKALEKRNYEKKMVDDLLSLDAQFRELTNQINQLRAQRNSISKMVAQAKSSGKTEEIENLTEEGKK
IGRQIDSIEDQLKEIKVQMEKLMLLVPNIPDDSVPEGKDETSNREIRKWGDPKKFDYNPQAHWDLGPSLGLMDFDRAAKL
SGSRFTVMYGMFAKLERALTNFMLDMHTKEHGYTEVWLPHIVKRETMTITGQLPKFEEEAYRIEADDLFLIPTAEVPLVA
LRSNEILEEKDLPLLYTAYTPCYRREAGSYGKDVRGMIRQHQFDKVELVWITTPERSFEDLETLVSHAEEVLRRLELPYR
VIQLCSGDLGFGAAKTYDLEVWLPSYNSYKEISSCSNDTDFQARRGNIRYRRKDGKISFVHTLNGSGVAVGRTLVAIIEN
YQRADGRIDVPKALQPYLGCEVLG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 7e-100 49