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Name : leuS (Tlet_1847) Accession : YP_001471465.1 Strain : Thermotoga lettingae TMO Genome accession: NC_009828 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : - Position : 1918645 - 1921092 bp Length : 2448 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : GTGCCGAGATATGAACCTCAAGAGATAGAAAGCAAATGGCAGAAATTTTGGGAAAAAGAAGGTTTGTTTAAAACACCTCA ACATTCTGATCTACCGAAATACTACATGCTCGTGATGTTCCCATATCCATCTGGTACGCTTCATGTGGGCCATGTGAAAA ATTACGTTATAGGTGATGCAGTTGCGCGCTACAAAAGAATGCGCGCCTACAACGTGTTGCATCCGTTTGGTTACGACGCC TTTGGGTTACCCGCAGAGAATGCCGCAATCGAGCGAAAAATCCATCCAAAAGATTGGACTTTGAACAATATAAATATCAT AAGAAGACAGATAAAGAAACTTGGTATCAGTTATGACTGGAACAGGGAAGTCATAACCTGTTTGGAATCTTACTACAAAT GGACTGAATGGATCTTTTTGAAATTATATGAAGCCGGGCTTGCCTATAAGAAAAAAGCGGCGGTGAACTGGTGCCCGAAG TGCATGACATCGCTTGCAAATGAGCAGGTAAAAGACGGAAGATGTGAACGGTGTGATACACCGGTTACCATAAAGCATCT TGAGCAATGGTTTTTCAAGATAACAGACTATGCAGAGAGACTTTTGAAAGATCTGGATAAGCTTACCGGGTGGCCAGAAC ATGTAAAAACAATGCAGAGAAACTGGATTGGTGAGAGCAAGGGAGCAAAAATTTCGTTCAAAGTTGAAGAATCAGAGATG AATATAGAGGTTTTCACCACGAGACCCGATACACTCTGGGGTGTAACTTTTATGGTGCTTGCACCCGAATCTGATCTTGT TAATCACATAACGCTTCCAGAATTAAAAGGGGAACTTGAGAAATTTTTGAATTATGTCGGGCAACAGGATAGACATAAAA GAGGCTCAGCAGATGTTGAAAAAGAGGGATTTTTTACGGGAAGGTACGCGATCAACCCGGTTAGCGGTGAAAGAATTCCA ATATATGTTGCAAATTATGTTTTGATGGAATACGGTACAGGGGCTGTGATGGGTGTTCCCGCTCATGATCAGAGAGATTA CGAGTTTGCTGTTAAGTACAATTTGCCTATAAAAGAAGTTATAAAGCCATCCGAGGATATTCCAAAAAATAGGGCTTATG ATGGCCCGGGGATTATGGTTAACAGTGGTCCACTGAATGGTACTGTTGTGCCTGAAGGTATAGAAAGAGTTATCCAATGG CTTGAAGAAAGGGGCATAGCGAAAAGATCTGTACAGTACAAATTAAGGGACTGGCTTATTTCAAGGCAACGGTACTGGGG GGCTCCTATTCCAATTGTCTATTGTGAAAAATGTGGGATGGTACCTGTTCCGGAGAAATCTCTCCCAGTTCAATTACCTT ACGATGTTGAGTTTCTTCCAACGGGTCAGTCGCCTCTAATGCTGAACGATGAATTTAGAAAAACTTCATGCCCAAAATGT GGTGGTCCCGCTCTCAGAGATGCTGACACGATGGATACTTTTGTTGATTCTTCATGGTATTTTCTGAGATATGTTAACCC GGATCGGGATGATGTGCCTTTCGTGAAAGAAGATGTCGATCACTGGTTGCCTGTTGATCAATATGTTGGTGGTGTAGAAC ATGCCGTTTTGCATTTGCTTTATTCAAGATTCATAACGAAAGTGCTCTATGATCTTGGATACCTGAGTTTCGATGAGCCG TTTGAAAATCTCTTTACTCAGGGAATGATATATAAAGACGGCGCCAAGATGTCTAAGAGCAAAGGTAATGTTGTCTCACC TGATGAAATGATTGACAGGTATGGAGCTGATACTCTCAGAATGTATATCCTTTTTATGGGACCGCCTGAGAGAGATGCAG AATGGAATGATGCAGGAATAGAAGGTGTATATAGATTTATAAGGAGAGCTTGGTCTCTTATGGATCAGATAATATCTCTA CCAGATAATCAGAATCAGGTGTTTGCGGAAGAAGAGAAACATCTTCGTAGAAAACTCCATATATCCCTGAGAAAGGTTAC CCAGGATATGGAAGGAGGATTCAAATTTAACACAGTTGTCAGTAGCTTGATGGAGCTGGTGAACGATGCTTATGATTACA TAGACAACTTACCGCAGCATCGGTGGAATATAAAGTTGTTGAAAGAACTTGCTAAAAATTTTGTGCTTATGATATCTCCC TTTGCACCTCATTTTGCTGAGGAGCTCTGGCAAAGAATGGGCTATAGCTCGTCAGTAATGAAAGAAAAATGGCCTGAATA TGATCCGGATGCACTTGTTGTCGAAGAAGTTGAAATAGCAATCCAGGTAAATGGAAAACTGAGAGATAAAGTAAAGATTC CTGTAGATGCTACAGAAGATCAGATAAAAGAAATCGCGTTAAAGAGTGAAAAAGTGCGAAAGTATATCAGCGATGAGCCA AAAAAAATAATTTATGTTCCAAAAAGATTGTTGAACATAATTTTTTAA Protein sequence : MPRYEPQEIESKWQKFWEKEGLFKTPQHSDLPKYYMLVMFPYPSGTLHVGHVKNYVIGDAVARYKRMRAYNVLHPFGYDA FGLPAENAAIERKIHPKDWTLNNINIIRRQIKKLGISYDWNREVITCLESYYKWTEWIFLKLYEAGLAYKKKAAVNWCPK CMTSLANEQVKDGRCERCDTPVTIKHLEQWFFKITDYAERLLKDLDKLTGWPEHVKTMQRNWIGESKGAKISFKVEESEM NIEVFTTRPDTLWGVTFMVLAPESDLVNHITLPELKGELEKFLNYVGQQDRHKRGSADVEKEGFFTGRYAINPVSGERIP IYVANYVLMEYGTGAVMGVPAHDQRDYEFAVKYNLPIKEVIKPSEDIPKNRAYDGPGIMVNSGPLNGTVVPEGIERVIQW LEERGIAKRSVQYKLRDWLISRQRYWGAPIPIVYCEKCGMVPVPEKSLPVQLPYDVEFLPTGQSPLMLNDEFRKTSCPKC GGPALRDADTMDTFVDSSWYFLRYVNPDRDDVPFVKEDVDHWLPVDQYVGGVEHAVLHLLYSRFITKVLYDLGYLSFDEP FENLFTQGMIYKDGAKMSKSKGNVVSPDEMIDRYGADTLRMYILFMGPPERDAEWNDAGIEGVYRFIRRAWSLMDQIISL PDNQNQVFAEEEKHLRRKLHISLRKVTQDMEGGFKFNTVVSSLMELVNDAYDYIDNLPQHRWNIKLLKELAKNFVLMISP FAPHFAEELWQRMGYSSSVMKEKWPEYDPDALVVEEVEIAIQVNGKLRDKVKIPVDATEDQIKEIALKSEKVRKYISDEP KKIIYVPKRLLNIIF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 2e-164 | 43 |
