Gene Information

Name : guaA (CCC13826_1555)
Accession : YP_001466431.1
Strain : Campylobacter concisus 13826
Genome accession: NC_009802
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 5.4.2.1
Position : 537602 - 539134 bp
Length : 1533 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGAACAATACGATTATAGTTTTGGACTTTGGTTCGCAGTATACTCAGCTAATAGCTAGAAGGCTAAGAGAAGAAGGAGT
TTATACTGAAATTTTGCCATTTAATGCAAAACTAAGCGATATAAAGGCGAAAGATCCAAAAGGTATCATTCTAAGTGGTG
GTCCAGCTAGCGTTTATGCCAAAGATGCCTACTTTTGCGATAACGGCGTCTTTGAGCTAAATATCCCTATACTTGGCGTT
TGCTACGGCATGCAGCTACTTGCTCACACACATGGTGCTGAGGTTTTAGCAGCTGATCACAAAGAGTACGGCAAGGCTGA
ACTTAGCGTCGTAAAAGAGCACGATCTTTTTAAAGATACACCTTCAAAACAAATCGTATGGATGAGCCATAGCGACTATG
TAAAAGACCTGCCAAAGGGCTTTGAGGCGATTGCGATTAGCGAAAATTCGCCTTATTGCGCTTTTGGCGATGATAAGCGT
AAATTTTATGCGATCCAGTTTCATGCAGAGGTGCAACACAGCGAGTATGGCACGCAAATTTTAAAGAATTTTGCTAAATA
TATCTGTGGCTGCGAGAGCACTTGGAACATGGGAAGCTTCGCTAAAAATAAGATAGAAGAGATCAGAAAAACAGTGGGCA
CTCACAAGGTGCTTTGCGCAGTTAGCGGTGGCGTGGATAGCTCTGTGACTGCGGCACTTTTGGCGGCTGCTGTGCCTGAA
AATTTGATCCTTGTTTTTGTTGATAATGGACTTCTTAGGACAAACGAAAAAGAGCAGGTTGAGGCTACATTTAGAACAAA
ACTTGGCGTTGAGCTAGTTAGTATAGATGCGAGCGAGATCTTTCTTGGTCGCTTAGCTGGTGTCGTTGATCCTGAGAAAA
AACGCAAGATCATAGGCGAGACATTTATAGAAATTTTTGAAAAAGAGGCTAAGAAGCATGGCGATGTGAAATTTCTAGCT
CAAGGCACTCTTTATACCGATATCATCGAAAGCTCAGTCGTTGGCTCAAGCAAGACGATAAAGAGCCACCACAATGTTGG
AGGCTTGCCTGATTGGATGACATTTGAGCTGATAGAGCCTTTAAGAGAGATTTTTAAAGACGAAGTTAGAAAGCTAGGAC
TTGAGCTTGGGCTAAGCCGCGAGCTAGTCTTCCGCCACCCTTTCCCTGGACCTGGTCTTGCTATCCGCATCATGGGCGAG
GTAAATAAGCCAAGTCTTGAGCTACTTCGCAAAGCTGACGTGATATTACGTGACGAGCTAAAAAGCACTGGATGGTATAA
CAAAACTTGGCAGGCGTTCTGCGTGCTTCTAAACGTAAATTCAGTCGGCGTAATGGGCGATAATCGCACCTACGAAAACG
CTGTTTGTGTGCGCGTAGTAGACGCAAGTGACGGCATGACTGCAAGCTTTTCAAGGCTTCCTTATGATCTACTTGAAAAC
GTAAGCCGCCGCATCATAAACGAAGTAAATGGCATAAACCGCGTAGTTTATGATATCTCAAGTAAGCCACCTGCAACTAT
CGAGTGGGAGTAA

Protein sequence :
MNNTIIVLDFGSQYTQLIARRLREEGVYTEILPFNAKLSDIKAKDPKGIILSGGPASVYAKDAYFCDNGVFELNIPILGV
CYGMQLLAHTHGAEVLAADHKEYGKAELSVVKEHDLFKDTPSKQIVWMSHSDYVKDLPKGFEAIAISENSPYCAFGDDKR
KFYAIQFHAEVQHSEYGTQILKNFAKYICGCESTWNMGSFAKNKIEEIRKTVGTHKVLCAVSGGVDSSVTAALLAAAVPE
NLILVFVDNGLLRTNEKEQVEATFRTKLGVELVSIDASEIFLGRLAGVVDPEKKRKIIGETFIEIFEKEAKKHGDVKFLA
QGTLYTDIIESSVVGSSKTIKSHHNVGGLPDWMTFELIEPLREIFKDEVRKLGLELGLSRELVFRHPFPGPGLAIRIMGE
VNKPSLELLRKADVILRDELKSTGWYNKTWQAFCVLLNVNSVGVMGDNRTYENAVCVRVVDASDGMTASFSRLPYDLLEN
VSRRIINEVNGINRVVYDISSKPPATIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 2e-137 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 1e-137 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 2e-137 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-119 49