Gene Information

Name : pyk (CCC13826_0964)
Accession : YP_001466287.1
Strain : Campylobacter concisus 13826
Genome accession: NC_009802
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0469
EC number : 2.7.1.40
Position : 391172 - 392623 bp
Length : 1452 bp
Strand : +
Note : identified by match to protein family HMM PF00224; match to protein family HMM PF02887; match to protein family HMM TIGR01064

DNA sequence :
ATGATAAAAAAGACGAAAATTGTAGCGACTTTAGGGCCAGCAAGTGACAACGAAGAGACGATGGAAGCGATGGTTAAAGC
AGGGGTTAATGTCTTTCGTTTAAATTTTAGCCACGGAACACACGAATACCACAAATCAAACATCGACAAGATAAGAAACA
TCGAAAAAAGACTAAACAAACGCATAGGCATCTTGCAAGATATCTGCGGTCCAAAGATCAGAGTTGGCAAGCTTAGCGAG
CCATTTTACTTAAAAGCTGGCGACGAGCTTAGCATCTACGCAGAGGATATCGTGGGCGAGAAGATCGAAAAGGGCGTTTA
TAGAGTGAGCCTAAATCAGCCTCAAATTTTACCTATGCTAAAGGCTGGCGAGTACGTCTATCTCTACGATGGCTCGATCA
GAGCAAGAGTTGTAGGCGAGGGCAAAGATGTGGTAAAAACCATCATCGAAAATGACGGAATTTTAAACTCAAACAAAGGG
GTAAATTTCCCAAATACTACCCTTGGTATCGAGATCATCACGCCAAAAGATAAAGAAGATATGGAATTTGGCGCAAAGCA
GGGCGTAAATTTCGTCGCCATTAGCTTCGTGCAAGACGCAAATGACGTGATAAAAGCGAGAAATATCTTAAAAGAATTTG
GCTCCAAAGCGGCTATCTTATCTAAGATAGAGAAATTTGACGCGGTTGAAAACATAGACGACATCATCGCAAAGAGCGAT
GGTATCATGGTAGCTCGTGGCGATCTTGGCATAGAAGTGCCATTTTACAAGGTGCCAACCATACAAAAGCTCATCATCAA
AAAGGCAAATGCAGCCAGCAAGCCAGTCATCACAGCAACTCAGATGATGCTAAGCATGGCAGAGCATGAAACTGCCACAA
GAGCGGAGATAAGCGACGTGGCAAACGCCGTGCTAGACGGCACTGATGCGGTTATGCTAAGCGAGGAGAGCGCGATCGGC
AAAAACCCAGTCGCGGTCGTAGAGGCGATGAGCAAAACGATCATCCAGACGCAAAGCATCTATCCATACAATAAATTTGA
CGAATTTGACTTTTTTGACGAGACTGACATGGTCGCAAATAGCGCAGCTTCGCTAGCTGTTCGCATCAAGGCAAATGCGA
TACTCTCTATCACAGGCTCAGGCAAATCAGCTATAAAGCTAGCTAGAAACCGCACAAATATCGACATCATCGCTATCGCG
CACGACGAGCAGACAGCTCACATGCTGACCCTTGCTTGGGGCGTGACGCCAGCGCTTGTGCTTGAAAAGACAAAGCTAAA
TGTCCTTCTCGCAAATGTCATCAAAAAGGCTTATGATGCTGGATATGTCGAGCATGACAAGACCTATCTCGTCACAGCTG
GCCACCCAACAGGTGTAGAGGGCAGCACAAACCTCATACGTATCATTAGACGCGACCAGCTTGATTATTACCTAGACCTT
GCAACCGAGTAA

Protein sequence :
MIKKTKIVATLGPASDNEETMEAMVKAGVNVFRLNFSHGTHEYHKSNIDKIRNIEKRLNKRIGILQDICGPKIRVGKLSE
PFYLKAGDELSIYAEDIVGEKIEKGVYRVSLNQPQILPMLKAGEYVYLYDGSIRARVVGEGKDVVKTIIENDGILNSNKG
VNFPNTTLGIEIITPKDKEDMEFGAKQGVNFVAISFVQDANDVIKARNILKEFGSKAAILSKIEKFDAVENIDDIIAKSD
GIMVARGDLGIEVPFYKVPTIQKLIIKKANAASKPVITATQMMLSMAEHETATRAEISDVANAVLDGTDAVMLSEESAIG
KNPVAVVEAMSKTIIQTQSIYPYNKFDEFDFFDETDMVANSAASLAVRIKANAILSITGSGKSAIKLARNRTNIDIIAIA
HDEQTAHMLTLAWGVTPALVLEKTKLNVLLANVIKKAYDAGYVEHDKTYLVTAGHPTGVEGSTNLIRIIRRDQLDYYLDL
ATE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-53 41
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-52 41
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-53 41
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-53 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_001466287.1 pyruvate kinase VFG0479 Protein 2e-53 41