Gene Information

Name : lysS (CCC13826_0225)
Accession : YP_001467461.1
Strain : Campylobacter concisus 13826
Genome accession: NC_009802
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG1190
EC number : 6.1.1.6
Position : 1635796 - 1637307 bp
Length : 1512 bp
Strand : +
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
GTGATATTTGACAACCAACACGAAATTCAAAGATTAGAAAGCATAGATGAGCTTAGAAATTTAGGCATAAATCCGTATCC
ACATTTTCTTAGAAGAGATATGAATATCTCTAAATTTAGACTTAAATTTAACTATATAAAAGATACAGAAGAGAAAAAAG
CAGAGGGGCAGCTAGTTGGCCTTGCAGGCAGGATAAAGCTGATCCGCGACGCCGGTAAAGCGGTCTTTGCAAACATCGAA
GACGAAAATGGAAATTTACAAATTTATTTTAGCAACAAGACGCTTGATCCAGAGTGGTTTAAAATCGTTAAAAAATATGT
AGAAATAGGCGACATTGTCTATGTTAGAGGCTACGCTTTTATAACAAGAACTGGCGAATTTTCAATGCACGTAAATGAGC
TTAGCTTAGCTACAAAATCAATTAGTCCGCTTCCTGAGAAGTACCACGGGCTAGTTGATGTTGAGACAAGATACCGCCAA
AGATACCTTGATATGATAATGAACCCTGAAGTTAGGGCTGATTTTAAAAAGCGCTCGGTGATTATAAGCACGATTAGAAG
ATTTTTTGAAGAAAAGGGCTTTTTAGAGGTTGAAACTCCGATGCTTCACCCAATAGCAGGCGGCGCAAATGCAAAGCCAT
TTGTGACATTTCACAACGCCCTTGGAGTTGAGAGATACCTAAGAATCGCTCCCGAGCTATATCTAAAACGCCTTGTAGTT
GGCGGCTTTGAAGCTGTTTATGAGATGAATAGAAACTTCAGAAACGAGGGCATGGATCTAACCCACAACCCTGAATTTAC
AAGTATCGAGTTTTACTGGGCATATCATAACTACCACGATCTAATGGGCATCACAGAGGATCTATTTAATGTCATTTTAG
AAAAGCTTGGCATGGAGAAAGTGATAAATTTTGATGGTATGGAGATTGATTTTAGCAAGCCATTTAAACGCATAAGCTAT
AAAAAAGCTCTAGTTGAGATCGGCGGACTTGCTGAAGATATCGTAAGCGATAAGGCTAAAATTTTAGCAAAACTAAGAGC
TGATGGCTTTGAAGCAAACGAGAAACTTGACCTTGGCCACTTGCAGGCTGAACTCTTTGACAACTACGTGGAGAGCAAGC
TCATCCACCCAACTTTTGTCATCGACTATCCGATCTCTATAAGCCCACTTTCAAGAAGAAGCGACACAAATCCTGATGTG
GCAGAGAGATTTGAGCTATTTATCGCTGGTCGTGAGCTAGCAAATGGCTTTAACGAGCTAAACGATCCAATCGATCAATA
CAACCGCTTTAAAGCGCAAATCGATGCCAAAAATGCAGGCGATGACGAGGCTCACGAAATGGATGAAGACTATGTAAAAG
CCCTAGGATACGGCATGCCACCAGTTGCAGGCGAAGGCATAGGCATCGATAGGCTTGTGATGCTTCTAACAGATAAAAAA
TCAATCCGCGACGTTGTCCTCTTCCCAGCGATGAGGCCACTAAAAACTGAGATAAAGGAGAACGAAAAATGA

Protein sequence :
MIFDNQHEIQRLESIDELRNLGINPYPHFLRRDMNISKFRLKFNYIKDTEEKKAEGQLVGLAGRIKLIRDAGKAVFANIE
DENGNLQIYFSNKTLDPEWFKIVKKYVEIGDIVYVRGYAFITRTGEFSMHVNELSLATKSISPLPEKYHGLVDVETRYRQ
RYLDMIMNPEVRADFKKRSVIISTIRRFFEEKGFLEVETPMLHPIAGGANAKPFVTFHNALGVERYLRIAPELYLKRLVV
GGFEAVYEMNRNFRNEGMDLTHNPEFTSIEFYWAYHNYHDLMGITEDLFNVILEKLGMEKVINFDGMEIDFSKPFKRISY
KKALVEIGGLAEDIVSDKAKILAKLRADGFEANEKLDLGHLQAELFDNYVESKLIHPTFVIDYPISISPLSRRSDTNPDV
AERFELFIAGRELANGFNELNDPIDQYNRFKAQIDAKNAGDDEAHEMDEDYVKALGYGMPPVAGEGIGIDRLVMLLTDKK
SIRDVVLFPAMRPLKTEIKENEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 1e-105 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_001467461.1 lysyl-tRNA synthetase VFG1668 Protein 6e-106 47