Gene Information

Name : ribD (EcE24377A_0445)
Accession : YP_001461596.1
Strain : Escherichia coli E24377A
Genome accession: NC_009801
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 1.1.1.193
Position : 466330 - 467433 bp
Length : 1104 bp
Strand : +
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
GTGCAGGACGAGTATTACATGGCGCGGGCGCTAAAGCTGGCGCAACGAGGACGTTTTACCACCCACCCCAACCCGAATGT
CGGGTGCGTCATTGTCAAAGATGGCGAAATTGTCGGTGAAGGTTACCACCAACGAGCGGGTGAACCACATGCCGAAGTAC
ACGCGTTGCGTATGGCGGGTGAAAAAGCCAAAGGCGCAACGGCGTATGTGACACTCGAACCCTGTAGCCATCATGGTCGT
ACGCCACCGTGCTGTGACGCACTCATCGCCGCTGGCGTAGCGCGCGTGGTTGCCTCGATGCAAGATCCTAACCCGCAGGT
CGCTGGGCGTGGACTTTACCGTCTGCAACAGGCTGGCATTGACGTCAGCCACGGGCTGATGATGAGTGAAGCCGAGCAAT
TGAATAAAGGCTTTCTCAAGCGGATGCGCACCGGCTTTCCTTATATTCAGTTAAAACTTGGCGCATCGCTTGATGGCCGC
ACGGCGATGGCGAGCGGCGAAAGCCAGTGGATCACTTCGCCTCAGGCGCGGCGCGACGTACAACGACAGCGCGCACAAAG
TTATGCCATTTTAACCAGCAGCGCCACGGTGCTGGCGGATGATCCAGCCTTAACAGTGCGTTGGTCTGAACTGGATGAAC
AAACTCAGGCGCTCTACCCGCAACAAAATCTCCGCCAGCCAGTACGTATTGTGATTGATAGCCAAAATCGCGTGCTGCCG
GAACATCGCATTGTGCAGCAGCCCGGCGAAACCTGGTTCGCGCGTACGCAGGAAGATTCTAGTGAGTGGCCGGAAACGGT
GCGTACCTTGCTGATTCCAGAGCATAAAGGTCATCTGGATCTGGTTGTACTGATGATGCAACTGGGTAAACAGCAAATTA
ACAGCATCTGGGTGGAAGCGGGGCCAACGCTCGCTGGCGCATTGCTGCAGGCGGGTTTAGTCGATGAGCTGATTGTCTAT
ATCGCACCTAAACTATTAGGCAGCGACGCCCGCGGATTATGCACGCTGCCAGGGCTTGAGAAATTAGCCGACGCCCCCCA
ATTTAAATTCAAAGAGATACGTCATGTAGGCCCGGATGTTTGCCTGCATTTAGTGGGTGCATGA

Protein sequence :
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVASMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQRQRAQSYAILTSSATVLADDPALTVRWSELDEQTQALYPQQNLRQPVRIVIDSQNRVLP
EHRIVQQPGETWFARTQEDSSEWPETVRTLLIPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVY
IAPKLLGSDARGLCTLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 2e-60 47
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 2e-60 47