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Name : EcE24377A_2911 (EcE24377A_2911) Accession : YP_001463946.1 Strain : Escherichia coli E24377A Genome accession: NC_009801 Putative virulence/resistance : Unknown Product : HsdR family type I site-specific deoxyribonuclease Function : - COG functional category : V : Defense mechanisms COG ID : COG0610 EC number : - Position : 2915437 - 2918676 bp Length : 3240 bp Strand : + Note : identified by match to protein family HMM PF04313; match to protein family HMM PF04851; match to protein family HMM TIGR00348 DNA sequence : ATGGCAAAGATGACCGAATCCGATATTGAAGTAATGGTAATTGAGCACCTGCAAGGGCTGGGCTATGAGTATGTTTACGG CCCGGACATTGAACCCAGTGGCATCAATCCGTTACGTAGCTATCAGCAGGTTATCCTTGAAGATAAGGTGCGTATTGCTC TACAACGCCTGAATCCGCACCTTAGTGAACAGAAGTGTGAGGAAGCCCTGAAACAGGTGATGCAGATCAGCACACCTGAT CTAATGGCAAACAATCTGGCCTTTCATCGCCTGTTGACCGAAGGGATCAATATCGAAGTCAGTAAGGATGGTAATACACA AGGAGAGCTGGCCTGCCTGATCGACTTTAACGATCCCACTAATAATGAATTTCTGGTCATTAATCAGCTCACCATCAAAG AAGGCAATCATACCCGCCGACCTGATCTTATTTTATTCATCAACGGCCTGCCATTAGTCGTTATCGAACTTAAAAATGCC GCTGACGAAAATGCTACGGTAACAGGTGCCTATAATCAGATTAAAACCTATCAGAACCAAATCCCCGTTCTGTTTAACTA CAATGCTTTTAATGTGATATCTGACGGGCTGGAAGCCAAAGCGGGGACGGTTTCTGCCGATTTCAGTCGTTATATGACAT GGAAAACCGCTAATGGTAAAACACAAGCTACCAGTACCCAACCACAGCTCGAAGTTTTATTACAGGGATTGCTTAATCCT GTAACGCTGTTGGATGTGATCCGCCACTTTATCGTGTTTGAAGCCAGCAAACATGAAGACAGCAAAGGGATTATCAGTAT CCGTACCGTTAAAAAAATGGCTGCTTATCACCAGTACTACGCGGTTAATGCAGCAGTACTTTCCACTATTCGTGCCTCAG GTGTAAATGCAGATTCCCCCTCTGCCGAAGTAGCACTGCGCCAGCAGGGACGTAACAGTAAAGTTCTTGTTAATGCGCAA AAAACCGGAGATCGTAAAGCGGGGGTCGTGTGGCATACCCAGGGTTCCGGTAAATCGCTTTCGATGGTGTTTTATACCGG GAAGATTGTACTGGCGCTGAATAATCCAACAGTGGTAGTGATCACTGACCGTAACGATTTGGATGATCAGCTATTCGGTA CGTTTTCTTCTGCCACTCAGCTACTTCGTCAGACACCAAAACAGGCCGACAACCGGGAAGAACTCAAAGAATATTTGCGC GTAGCCTCTGGTGGTGTGGTGTTTACCACTATTCAAAAATTCCAGCCTAATGATGGCAGCAATATCTATGAGTTGTTGTC AGACAGAACCAATATTGTCGTTATCGCTGATGAAGCCCACCGTTCACAATACGGTTTCAGCGCCAAAGAAGTTGACGTGA AAGACAGTGAAGGCAACGTTACAGGTAAGCGCACTGTTTATGGCTTTGCCAAATATATGCGTGATGCCTTACCTAATGCG ACCTATCTCGGCTTTACCGGAACCCCCATAGAAAAAACGGACGTCAACACGCCTGCTGTTTTTGGTAACTATGTTGATAT CTACGATATCTCGCAGGCCGTTGAAGATGGTGCAACAGTTCGTATCTTTTATGAAAGCCGTCTTGCCAAAATTGCCATCA GTGATGAAGGTCGTCAGCTTATTGAAGACTTTGATGATGAGTTTAACGAGGACGAACTGACGCTCACGCAAAAAGAACGT TCTAAATGGGCCAGAATCGAAGGTTTGATTGGCAGTTCAAAACGTATTAAAGCGATTGCGGCGGATATGGTTCTGCACTT TGAGCAGCGCTTAAAATCCAATGCCGATCATGGTAAGGGCATGATTGTTACCATGTCCCGCCGTATTGCTGCTGAACTAT ATAAAGAAATCATAGCCTTAAAACCTGAATGGCACAGCGATGATTTAAATGACGGTATAATAAAAGTCGTCATGACCTCT TCTGCTGCTGACGGGCCAGAAATTGCCAAACACCACACCACAAAAAAAGAACGTCAGGTTCTGGCTAACCGTATGAAGGA TGACGACGACAAGCTGAAACTGGTGATAGTGCGTGATATGTGGTTAACCGGCTTCGACGCTCCCAGCATGCATACGCTGT ATATCGACAAACCAATGAAAGGCCACAACCTTATGCAGGCAATTGCCCGTGTGAACCGTGTGTATAAAGATAAGATAGGC GGTCTGGTTGTTGACTATCTGGGCATTGCCTCTGATTTAAAAGAAGCCCTCTCCTTTTACTCTGATGCAGGTGGACGTGG AGATCCTGCTGAGGTTCAGGAAGAAGCCGTAACGCTCATGCAGGAAAAGCTGGAAATCCTGGAAGGCATGATGCATGGAT ACGATTACAAAGCTTACTTTGCCGCAACTACCTCACAACGCCTGACAATTATTCTTGAATCAGAAAACCATATTTTAGGG CTGGATAACGGTAAAGGTAAAATGCGTTTCCTGGCTGCGGTTGCAGCCTTGTCGCAGGCATTTGCATTGGCGACACCGCA CGATAAAGCAATGGAAGCGGCACCCGAAGTAGCATTCTTCCAGGCAGTAAAAGCCAGACTGAATAAATTTACTGAAAACT CAGACGGATCAGAAGAAGAACACAATGACAGTCTGGAAGTTCGGGTAAAACAGACTATCGATCAGGCTCTGGTTACCGAT AAAGTTGTTGATATTTTTGACGCTGCTGGGATACAAAAGCCTGATATTTCCGTTCTTTCTGAAGAATTCCTTCAGGAAAT GAAGGATTACCAACACAGAAATATTGCTTTGGAAACGCTTAAAAAACTGCTTTCTGACGAGATCAAGGTTCGCTCGAATC AAAGTATCACCCAAGGCAAAAAACTGATTGATATGCTGACCTCTGCAATCAATGGCTACCAGAACAAGGTACTGACCGCA GCGGAGGTAATTGATGAGCTAATCAAGCTTGCCAAGACTATCCAGGAATCTGACAGCCTTGCCAGCCAGTTAAACCTCAG CGCTTATGAATATGCCTTCTATTCTGCTGTTGCAGATAACGACAGTGCTCGCGAGTTAATGGAAAAGGAAAAACTACGAG AACTGGCAGTCGTACTTACAGAGGCTATCCGCAACAATGTCAGTCTTGACTGGACAGTGAAAGAAGCAGCAAGAGCAAAA ATTCGCGTGGTGGTAAAACGTCTGCTCAAAAAATATGGTTATCCACCCGATATGTCCTTGCTCGCCACAGAGACCATTTT GAAGCAGGCTGAACTTTTAGCTGGAGAATTAGGAAAATGA Protein sequence : MAKMTESDIEVMVIEHLQGLGYEYVYGPDIEPSGINPLRSYQQVILEDKVRIALQRLNPHLSEQKCEEALKQVMQISTPD LMANNLAFHRLLTEGINIEVSKDGNTQGELACLIDFNDPTNNEFLVINQLTIKEGNHTRRPDLILFINGLPLVVIELKNA ADENATVTGAYNQIKTYQNQIPVLFNYNAFNVISDGLEAKAGTVSADFSRYMTWKTANGKTQATSTQPQLEVLLQGLLNP VTLLDVIRHFIVFEASKHEDSKGIISIRTVKKMAAYHQYYAVNAAVLSTIRASGVNADSPSAEVALRQQGRNSKVLVNAQ KTGDRKAGVVWHTQGSGKSLSMVFYTGKIVLALNNPTVVVITDRNDLDDQLFGTFSSATQLLRQTPKQADNREELKEYLR VASGGVVFTTIQKFQPNDGSNIYELLSDRTNIVVIADEAHRSQYGFSAKEVDVKDSEGNVTGKRTVYGFAKYMRDALPNA TYLGFTGTPIEKTDVNTPAVFGNYVDIYDISQAVEDGATVRIFYESRLAKIAISDEGRQLIEDFDDEFNEDELTLTQKER SKWARIEGLIGSSKRIKAIAADMVLHFEQRLKSNADHGKGMIVTMSRRIAAELYKEIIALKPEWHSDDLNDGIIKVVMTS SAADGPEIAKHHTTKKERQVLANRMKDDDDKLKLVIVRDMWLTGFDAPSMHTLYIDKPMKGHNLMQAIARVNRVYKDKIG GLVVDYLGIASDLKEALSFYSDAGGRGDPAEVQEEAVTLMQEKLEILEGMMHGYDYKAYFAATTSQRLTIILESENHILG LDNGKGKMRFLAAVAALSQAFALATPHDKAMEAAPEVAFFQAVKARLNKFTENSDGSEEEHNDSLEVRVKQTIDQALVTD KVVDIFDAAGIQKPDISVLSEEFLQEMKDYQHRNIALETLKKLLSDEIKVRSNQSITQGKKLIDMLTSAINGYQNKVLTA AEVIDELIKLAKTIQESDSLASQLNLSAYEYAFYSAVADNDSARELMEKEKLRELAVVLTEAIRNNVSLDWTVKEAARAK IRVVVKRLLKKYGYPPDMSLLATETILKQAELLAGELGK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdR | YP_251977.1 | type I restriction-modification system restriction subunit | Not tested | SCCmec | Protein | 0.0 | 46 |
| hsdR | BAH57699.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-VII SCCmec | Protein | 0.0 | 46 |
| hsdR | BAD24840.1 | type I restriction-modification system endonuclease homologue | Not tested | Type-V SCCmec | Protein | 0.0 | 46 |
| api52 | CAF28526.1 | hsdr-like Type I restriction enzyme | Not tested | YAPI | Protein | 0.0 | 46 |
