Gene Information

Name : ribD (EcHS_A0485)
Accession : YP_001457253.1
Strain : Escherichia coli HS
Genome accession: NC_009800
Putative virulence/resistance : Unknown
Product : bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0117
EC number : 1.1.1.193
Position : 497247 - 498350 bp
Length : 1104 bp
Strand : +
Note : riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway; catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2,5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine a

DNA sequence :
GTGCAGGACGAGTATTACATGGCGCGGGCGCTAAAGCTGGCGCAACGAGGACGTTTTACCACGCATCCCAACCCGAATGT
CGGGTGCGTCATTGTCAAAGATGGCGAAATTGTCGGTGAAGGTTACCACCAACGTGCGGGTGAACCACATGCCGAAGTAC
ACGCGTTGCGTATGGCGGGTGAAAAAGCCAAAGGTGCGACCGCCTATGTCACACTCGAACCCTGTAGCCATCATGGTCGT
ACGCCACCGTGCTGTGACGCACTCATCGCCGCTGGCGTAGCGCGCGTGGTTGCCTCGATGCAAGATCCTAACCCGCAGGT
CGCTGGGCGTGGACTTTACCGTCTGCAACAGGCTGGCATTGACGTCAGCCACGGGCTGATGATGAGTGAAGCCGAGCAAT
TGAATAAAGGCTTTCTCAAGCGGATGCGCACCGGCTTTCCTTATATTCAGTTAAAACTTGGCGCATCGCTTGATGGCCGC
ACGGCGATGGCGAGCGGCGAAAGCCAGTGGATCACTTCGCCTCAGGCGCGGCGCGACGTACAACGACAGCGCGCACAAAG
TCATGCCATTTTAACCAGCAGCGCCACGGTGCTGGCGGATGATCCAGCCTTAACAGTGCGTTGGTCTGAACTGGATGAAC
AAACTCAGGCGCTCTACCCGCAACAAAATCTCCGCCAGCCAGTACGTATTGTGATTGATAGCCAAAATCGCGTGACGCCG
GAACATCGCATTGTGCAGCAGCCCGGCGAAACCTGGTTCGCGCGTACGCAGGAAGATTCTAGTGAGTGGCCGGAAACGGT
GCGTACCTTGCTGACTCCAGAGCATAAAGGTCATCTGGATCTGGTTGTACTGATGATGCAACTGGGTAAACAGCAAATTA
ACAGCATCTGGGTGGAAGCGGGGCCAACGCTCGCTGGCGCATTGCTGCAGGCGGGTTTAGTCGATGAGCTGATTGTCTAT
ATCGCACCTAAACTATTAGGCAGCGACGCCCGCGGATTATGCACGCTGCCAGGGCTTGAGAAATTAGCCGACGCCCCCCA
ATTTAAATTCAAAGAGATACGTCATGTAGGCCCGGATGTTTGCCTGCATTTAGTGGGTGCATGA

Protein sequence :
MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQRAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGR
TPPCCDALIAAGVARVVASMQDPNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
TAMASGESQWITSPQARRDVQRQRAQSHAILTSSATVLADDPALTVRWSELDEQTQALYPQQNLRQPVRIVIDSQNRVTP
EHRIVQQPGETWFARTQEDSSEWPETVRTLLTPEHKGHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVY
IAPKLLGSDARGLCTLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00289 YP_008207754.1 Pyrimidine deaminase Not tested AbaR25 Protein 3e-61 47
BJAB0868_00293 YP_008211619.1 Pyrimidine deaminase Not tested AbaR26 Protein 3e-61 47