Gene Information

Name : EcHS_A2489 (EcHS_A2489)
Accession : YP_001459144.1
Strain : Escherichia coli HS
Genome accession: NC_009800
Putative virulence/resistance : Virulence
Product : fimbrial usher family protein
Function : -
COG functional category : N : Cell motility
COG ID : COG3188
EC number : -
Position : 2493977 - 2496619 bp
Length : 2643 bp
Strand : -
Note : identified by match to protein family HMM PF00577

DNA sequence :
ATGCCTGATCATTCTCTTTTTCGATTACGGATTCTTCCGTGGTGCATTGCGCTGGCAATGTCAGGGAGTTATAGCAGTGT
CTGGGCTGAAGACGACATTCAGTTTGATTCCCGTTTTCTGGAATTAAAAGGCGACACAAAAATTGATCTGAAGCGTTTTT
CCAGCCAGGGATATGTTGAGCCCGGAAAATACAATTTACAGGTTCAACTAAATAAACAGCCATTGGCGGAAGAGTACGAT
ATTTACTGGTATGCTGGTGAAGATGACGCGAGCAAAAGCTATGCTTGTCTGACACCGGAACTGGTAGCGCAGTTTGGTTT
AAAAGAAGACGTGGCGAAAAATCTGCAATGGAGCCACGATGCTAAATGCCTGAAATCCGGTCAACTGGAAGGCGTGGAAA
TTAAGGCTGATTTAAGCCAGTCCGCATTAGTCATTTCACTGCCACAGGCTTACCTCGAATATACTTATCCCGACTGGGAT
CCGCCTTCACGTTGGGATGACGGCATCTCCGGGATCGTCGCGGACTACAGCATCAACGCACAAACCCGGCACGAAGAAAA
TGGCGGTGATGATAGTAACGAGATCAGCGGCAACGGGACGGTCGGGGTTAACCTGGGGCCGTGGCGTATGCGTGCTGACT
GGCAGACTAACTATCAACATACTCGCAGTAATGATGACGATGAATTCAGCGGCGATGAAACTCAAAAAAAATGGGAGTGG
AGTCGCTACTATGCCTGGCGGGCGTTACCATCATTAAAAGCCAAACTGGCGCTGGGCGAGGATTACCTCAGATCCGATAT
TTTTGATGGTTTTAACTATGTTGGTGGCAGTGTCAGTACTGACGATCAAATGTTGCCTCCCAATCTGCGCGGCTACGCGC
CAGACATTTCCGGCGTGGCACACACCACAGCAAAAGTGACCGTCAGCCAGATGGGGCGTGTGATTTACGAAACGCAGGTT
CCGGCTGGACCGTTTCGTATTCAGGATCTTGGTGATTCTGTCTCCGGTACGTTGCATATTCGCATTGAAGAACAGAACGG
CCAGGTGCAGGAATATGACATCAGCACCGCCTCGATGCCATACCTCACTCGTCCAGGTCAGGTTCGCTATAAGATCATGA
TGGGCCGTCCGCAAGAGTGGGGACACCATGTCGAGGGTGAATTTTTTTCTGGTGCTGAAGCTTCCTGGGGGATCGCTAAC
GGCTGGTCGTTATATGGCGGCGCACTGGGAGATGAAAACTATCAGTCTGCGGCGCTTGGCGTCGGTCGCGATTTGTCTAC
ATTCGGCGCGGTCGCGTTTGATGTTACTCACTCGCACACCAAACTGGATAAAGACACCGCTTATGGCAAAGGTTCGCTGG
ACGGTAACTCCTTCCGTGTGAGTTATTCCAAAGACTTTGACCAGCTCAACAGCCGCGTTACTTTTGCTGGATATCGCTTC
TCGGAAGAGAACTTTATGACCATGAGCGAGTATCTGGATGCCAGTGACAGCGGAATGGTACGCACGGGCAACGACAAAGA
GATGTACACCGCCACTTATAACCAGAACTTCCGCGATGCGGGTGTTTCGGTTTATCTCAACTATACCCGCCATACCTACT
GGGATCGCGAGGAGCAGACAAACTACAACATCATGCTCTCGCACTATTTCAATATGGGCAGTATTCGTAATGTCAGCATC
TCGATGACTGGCTACCGTTACGAGTATGACAACCAGGCCGACAAAGGCATGTACATTTCGCTCAGTATGCCGTGGGGCGA
CAACAGTACCGTTAGCTATAACGGCAACTATGGCAGTGGGACGGACAGCAGTCAGGTCGGTTATTTCAGCCGTGTCGATG
ACGCGACTCACTATCAGTTGAACGTCGGCACCAGTGACAAACACACCAGCGTTGACGGCTATTACAGCCATGATGGTTCG
CTGGCGCAGGTTGACCTCAGCGCGAACTACCATGAAGGGCAATACACCTCTGCGGGCTTGTCGTTACAGGGCGGCGCAAC
GCTTACTGCCCACGGTGGCGCACTTCACCGTACCCAGAATATGGGCGGGACACGCTTGTTGATTGATGCCGATGGCGTTG
CCGATGTTCCGGTGGAAGGTAACGGGGCAGCTGTTTATACCAATATGTTTGGTAAGGCCGTCGTTTCTGACGTCAATAAC
TATTACCGCAATCAGGCGTATATCGACCTCAACAAACTGCCGGAAAACGCCGAAGCAACCCAGTCGGTGGTACAAGCCAC
GCTAACTGAAGGGGCGATTGGCTACCGCAAATTTACCGTCATCAGTGGTCAAAAAGCGATGGCGGTGCTGCGCCTGAGCG
ACGGCAGCCATCCTCCGTTTGGCGCAGAAGTAAAAAATGATAACGAGCAGACAGTGGGCCTTGTCGATGATGACGGCAAT
GTTTATCTGGCAGGGGTGAAACCTGGCGAACACATGAGTGTGTTCTGGAGTGGTGTTGCGCATTGCGATATCAACCTGCC
GGACCCGCTGCCTGCCGATCTGTTTAACGGCTTGTTACTGCCATGCCAGCATAAAGGCAATGTAGCACCTGTCACTTCGC
CGGCGGTCAAACCGGCGATTCAGGAACAGACACAGCGGGTGACGCCAACGGAACCCCCGACTTCAATTTCAGTAAACCAG
TAA

Protein sequence :
MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYD
IYWYAGEDDASKSYACLTPELVAQFGLKEDVAKNLQWSHDAKCLKSGQLEGVEIKADLSQSALVISLPQAYLEYTYPDWD
PPSRWDDGISGIVADYSINAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNYQHTRSNDDDEFSGDETQKKWEW
SRYYAWRALPSLKAKLALGEDYLRSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQV
PAGPFRIQDLGDSVSGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQVRYKIMMGRPQEWGHHVEGEFFSGAEASWGIAN
GWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYRF
SEENFMTMSEYLDASDSGMVRTGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNIMLSHYFNMGSIRNVSI
SMTGYRYEYDNQADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNVGTSDKHTSVDGYYSHDGS
LAQVDLSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMGGTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNN
YYRNQAYIDLNKLPENAEATQSVVQATLTEGAIGYRKFTVISGQKAMAVLRLSDGSHPPFGAEVKNDNEQTVGLVDDDGN
VYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPVTSPAVKPAIQEQTQRVTPTEPPTSISVNQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 5e-152 43
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 7e-151 43
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 9e-151 43
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 8e-152 43
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 7e-152 43
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 5e-152 43
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 3e-157 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EcHS_A2489 YP_001459144.1 fimbrial usher family protein VFG1548 Protein 3e-152 43
EcHS_A2489 YP_001459144.1 fimbrial usher family protein VFG0884 Protein 4e-152 43
EcHS_A2489 YP_001459144.1 fimbrial usher family protein VFG0895 Protein 2e-152 43