Gene Information

Name : CKO_00725 (CKO_00725)
Accession : YP_001452313.1
Strain : Citrobacter koseri ATCC BAA-895
Genome accession: NC_009792
Putative virulence/resistance : Unknown
Product : tyrosine kinase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG3206
EC number : -
Position : 700692 - 702854 bp
Length : 2163 bp
Strand : +
Note : Wzc; catalyzes the autophosphorylation on tyrosine residues which downregulates the biosynthesis of colonic acid (an extracellular polysaccharide)

DNA sequence :
ATGACAGAAAAAGTAAAACAGCTTGCCGCTCCGGTAACGGGCAGTGATGAAATCGATATCGGTCGCCTGGTGGGAACCGT
CATTGAAGCGCGCTGGTGGGTGCTTGGCATTACGGCGGTATTTGCGCTGTGCGCGGTGATTTACACGCTATTCGCCACGC
CGATTTACAGCGCCGACGCGCTGGTGCAAATCGAGCAAAATACCGGTAACTCGCTGGTGCAGGATATTGGCTCTGCGCTG
GCCAATAAACCGCCGGCATCAGAAGCGGAAATTCAGCTGATTCAGTCGCGTCTGGTTCTGGGGAAAACCGTTGACGATCT
CGACCTGGATATCTCCGTCACCAAAAACACCTTCCCGCTGTTTGGCGCAGGCTGGGAGCGCCTGATGGGGCGGCAGAATG
AGACGGTGAAAGTGACAACGTTCACCCGTCCAAAAGAGATGGGCGAGCAGGTTTTCACGCTTAACGTGCTGAGTGACAAA
ACCTACGAACTGACCAGCGACGGCGGCTTTAGCGCGCGCGGTCAGGCCGGGCAACTGCTGAGTAAAGATGGCGTGACGAT
GATGGTGAGCGCTATCCATGCCCGCCCGGACAGTGAATTTACCGTCACTAAATTCTCCACGCTTGGGATGATCAACAATC
TGCAAAACAACCTGACCGTGACGGAAAACGGCAAAGATACCGGCGTATTGAGCCTGGCCTTTACCGGTGAAGACAAGGAT
CAGATCCGCGATATTCTCAACAGCATCACCCGCAACTATCTCGAACAGAACGTTGAGCGGAAATCTGCGGAAGCGGCGAA
AAGCCTGGCGTTCCTGGCGAAACAGTTGCCGGAAGTGCGCAGTCGCCTGGACGTCGCGGAAAACAAACTCAACGCCTTCC
GTCAGGATAAAGACTCCGTGGACTTACCGCTGGAGGCCAAGGCGGTGCTGGATTCGATGGTGAATATCGACGCCCAGCTT
AACGAACTGACCTTCAAAGAGGCGGAAATCTCCAAGCTGTTTACTAAAGCGCATCCGGCTTACCGTACGCTGCTGGAAAA
ACGTAAAGCGCTGGAAGATGAAAAAGCCAAACTGAACGGGCGCGTGACGGCAATGCCGAAAACGCAGCAGGAAATTGTGC
GTCTGACGCGCGACGTCGAATCCGGTCAGCAGGTTTATATGCAACTGCTGAACAAGCAGCAGGAGCTGAAGATCACCGAG
GCCAGCACCGTCGGGGATGTGCGTATTGTTGACCCGGCGATTGCCCAGCCGGGCGTGCTGAAGCCGAAAAAAGCGCTGAT
TATTCTTGGCAGCATTATTCTTGGCCTGATGCTCTCTATCGTCGGCGTGTTGCTGCGTTCGCTGTTTAACCGTGGGATTG
AAAGTCCGCAGGTGCTCGAAGAACACGGCATCAGCGTCTATGCCAGCATTCCGCTGTCGGAGTGGCAGAAAGCGCGCGAT
AACGTCAAAACGATTAAGGGCGTTAAGCGCTACAAACAGAGCCAGTTGCTGGCGGTGGGGAATCCAACCGATCTGGCGAT
TGAGGCGGTGCGTAGCCTGCGTACCAGCCTGCATTTCGCCATGATGCAGGCGCAAAACAATGTGCTGATGTTGACCGGGG
TCAGCCCGTCTATCGGCAAAACCTTTGTCTGCGCCAACCTGGCGGCGGTCATCAGCCAGACCAACAAACGCGTGCTGCTG
ATCGACTGCGATATGCGTAAAGGCTATACCCACGAGCTGCTGGGCACCAACAACGTGAATGGTCTGTCCGACATTCTGGT
GGGCAAAGGGGATATCGCCTCCTGCGCCAAACCCACCTCCATCCCGCATTTCGATCTGGTGCCGCGCGGACAGGTGCCGC
CTAACCCGTCGGAACTGCTGATGAGCGAGCGCTTTGGCGAACTGATTGCCTGGGCCAGCGCGCACTATGACCTGGTCTTA
ATCGATACGCCGCCGATTCTGGCGGTGACCGATGCGGCGATCGTCGGACGGCATGTCGGCACCACGCTGATGGTGGCGCG
TTACGCTGTTAACACATTAAAAGAGGTGGAAACCAGCCTGAGCCGCTTTGAGCAGAACGGCATTCCGGTAAAAGGCGTAA
TCCTCAACTCCATCTTCCGACGGGCGACCGGTTATCAGGATTACGGTTACTACGAGTACGAATACAAGTCGGATTCAAAA
TAA

Protein sequence :
MTEKVKQLAAPVTGSDEIDIGRLVGTVIEARWWVLGITAVFALCAVIYTLFATPIYSADALVQIEQNTGNSLVQDIGSAL
ANKPPASEAEIQLIQSRLVLGKTVDDLDLDISVTKNTFPLFGAGWERLMGRQNETVKVTTFTRPKEMGEQVFTLNVLSDK
TYELTSDGGFSARGQAGQLLSKDGVTMMVSAIHARPDSEFTVTKFSTLGMINNLQNNLTVTENGKDTGVLSLAFTGEDKD
QIRDILNSITRNYLEQNVERKSAEAAKSLAFLAKQLPEVRSRLDVAENKLNAFRQDKDSVDLPLEAKAVLDSMVNIDAQL
NELTFKEAEISKLFTKAHPAYRTLLEKRKALEDEKAKLNGRVTAMPKTQQEIVRLTRDVESGQQVYMQLLNKQQELKITE
ASTVGDVRIVDPAIAQPGVLKPKKALIILGSIILGLMLSIVGVLLRSLFNRGIESPQVLEEHGISVYASIPLSEWQKARD
NVKTIKGVKRYKQSQLLAVGNPTDLAIEAVRSLRTSLHFAMMQAQNNVLMLTGVSPSIGKTFVCANLAAVISQTNKRVLL
IDCDMRKGYTHELLGTNNVNGLSDILVGKGDIASCAKPTSIPHFDLVPRGQVPPNPSELLMSERFGELIAWASAHYDLVL
IDTPPILAVTDAAIVGRHVGTTLMVARYAVNTLKEVETSLSRFEQNGIPVKGVILNSIFRRATGYQDYGYYEYEYKSDSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
orf41 AAO18066.1 Orf41 Not tested TTSS locus Protein 4e-160 49