Gene Information

Name : thyA (CKO_04194)
Accession : YP_001455691.1
Strain : Citrobacter koseri ATCC BAA-895
Genome accession: NC_009792
Putative virulence/resistance : Unknown
Product : thymidylate synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0207
EC number : -
Position : 3899542 - 3900336 bp
Length : 795 bp
Strand : -
Note : ThyA; catalyzes formation of dTMP and 7,8-dihydrofolate from 5,10-methylenetetrahydrofolate and dUMP; involved in deoxyribonucleotide biosynthesis; there are 2 copies in some Bacilli, one of which appears to be phage-derived

DNA sequence :
ATGAAACAGTATTTAGAACTGATGCAAAAAGTGCTGGATGAAGGCACACAGAAAAACGACCGTACCGGAACCGGAACGCT
TTCCATTTTTGGTCATCAGATGCGTTTTAACCTGCGGGAAGGATTTCCGCTGGTGACGACGAAGCGCTGCCATTTACGCT
CCATCATTCACGAGCTGTTGTGGTTCCTGCAAGGCGATACCAACGTCGCTTACCTGCATGAAAACAATGTGACGATCTGG
GACGAATGGGCCGATGAAAACGGTAATTTAGGCCCGGTATATGGCAAACAGTGGCGCGCATGGCCTGCGCCGGACGGTCG
CCATATTGACCAGATCACCACGGTCATGAACCAGTTGAAAAATGACCCGGACTCCCGCCGTATTATTGTTTCCGCCTGGA
ACGTCGGCGAGCTGGATAAAATGGCGCTGGCGCCGTGTCATGCGTTCTTCCAGTTCTATGTTGCGGACGGCAAACTCTCC
TGCCAGCTGTATCAGCGCTCCTGCGACGTCTTCCTGGGGCTGCCGTTTAATATCGCCAGCTATGCGTTACTGGTGCATAT
GATGGCGCAACAGTGCGACCTGGAAGTGGGCGACTTTGTCTGGACCGGCGGCGACACGCACCTGTACAGCAACCATATGG
AACAGACGCATCTACAGTTAAGCCGCGAACCGCGCGCGCTGCCGAAACTGGTGATCAAACGTAAGCCTGACTCTATCTTC
GACTACCGTTTTGAAGATTTTGAGATTGAAGGCTACGACCCGCATCCTGGCATTAAAGCGCCGGTCGCTATCTGA

Protein sequence :
MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLREGFPLVTTKRCHLRSIIHELLWFLQGDTNVAYLHENNVTIW
DEWADENGNLGPVYGKQWRAWPAPDGRHIDQITTVMNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMEQTHLQLSREPRALPKLVIKRKPDSIF
DYRFEDFEIEGYDPHPGIKAPVAI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thyA YP_001800914.1 thymidylate synthase Not tested Not named Protein 4e-88 66