Gene Information

Name : leuS (CKO_02514)
Accession : YP_001454059.1
Strain : Citrobacter koseri ATCC BAA-895
Genome accession: NC_009792
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : -
Position : 2320627 - 2323233 bp
Length : 2607 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAAAACAGGACCACTGGCTGCCATGCAAGAGCAATACCGCCCGGAAGAGATAGAATCAAAAGTCCAGCAACACTGGGA
CGAGAAGCGCACCTTTGAAGTAACCGAAGACGAGAGCAAAGAGAAGTATTACTGCCTGTCGATGCTTCCCTATCCTTCTG
GTCGACTACACATGGGCCATGTGCGTAACTACACCATCGGTGATGTGATTGCCCGCTACCAACGCATGCTGGGTAAAAAC
GTTTTACAGCCCATCGGCTGGGATGCTTTCGGCCTGCCTGCTGAAGGCGCGGCGGTGAAAAACAACACGGCGCCGGCGCC
GTGGACCTATGACAACATCGCCTACATGAAAAACCAGCTCAAAATGCTGGGCTTCGGCTATGACTGGAGCCGCGAGCTGG
CGACCTGCACCCCGGAATACTACCGCTGGGAGCAAAAATTCTTCACCGAACTGTATAAAAAAGGCCTGGTGTACAAAAAG
ACCTCTGCGGTGAACTGGTGCCCGAACGACCAGACCGTACTGGCGAACGAGCAGGTTATCGACGGCTGCTGCTGGCGCTG
CGACACCAAAGTTGAGCGTAAAGAGATCCCGCAGTGGTTCATTAAGATCACCGCCTACGCCGACGAACTGCTGAACGATC
TGGATAAACTGGATCACTGGCCAGACACCGTTAAAACCATGCAGCGCAACTGGATCGGCCGTTCTGAAGGCGTCGAGATC
ACTTTTGACGTGAACGGCTACGACAATACGCTGACGGTGTACACCACGCGTCCAGACACGTTCATGGGCGCCACTTACCT
GGCGGTCGCCGCAGGTCACCCGCTGGCGCAGAAAGCGGCTGCCAACAACCCGGAACTGGCTGCCTTTATCGACGAATGCC
GCAACACCAAAGTGGCGGAAGCCGATATGGCGACGATGGAGAAAAAAGGCGTCGACACCGGTTTTAAAGCCATTCACCCG
CTGACCGGCGAAGCGATCCCGGTATGGGCCGCCAACTTCGTGCTGATGGAGTACGGTACCGGTGCGGTCATGGCCGTTCC
GGGCCACGATCAGCGCGACTACGAATTTGCCACCAAATATGGCCTGACCATCAAGCCGGTTATCCTGGCGGCGGACGGCT
CTGAACCGGATCTGTCCGAGCAGGCGCTGACCGAGAAAGGCGTACTGTTTAACTCCGGCGAATTTAACGGTCTGGGCTTT
GAAGACGCCTTCAACGCGATTGCCGATAAACTGGCGGCGAAAGGCGTCGGCGAGCGTAAAGTCAACTACCGTCTGCGCGA
TTGGGGCGTTTCCCGTCAGCGTTACTGGGGCGCGCCGATTCCGATGGTGACTCTGGAAGACGGCACCGTTCTGCCGACCC
CGGAAGATCAACTGCCGGTCATCCTGCCGGAAGATGTCGTCATGGACGGCATCACCAGCCCGATCAAAGCCGATCCTGAG
TGGGCGAAAACCACCGTTAACGGTCAGCCTGCGCTGCGTGAAACCGACACCTTTGACACCTTTATGGAGTCCTCCTGGTA
CTACGCGCGCTACACCTGCCCGCAGTACAACGAAGGGATGCTGGACCCGGAAGCAGCAAATTACTGGCTGCCGGTCGATA
TCTACATCGGCGGTATTGAACACGCGATCATGCACCTGCTCTACTTCCGCTTCTTCCACAAGCTGATGCGCGACGCGGGC
ATGGTGAACTCTGACGAACCGGCGAAACAGCTACTGTGCCAGGGTATGGTGCTGGCAGACGCATTCTACTATGTAGGCGA
AAACGGCGAGCGTAACTGGGTTTCCCCGGTTGATGCCATCGTTGAGCGCGACGAGAAAGGCCGCATCGTTAAGGCGAAAG
ACGCGGCGGGCCATGAGCTGGTGTACACCGGCATGAGCAAGATGTCCAAGTCCAAAAACAACGGCATCGACCCGCAGGTA
ATGGTTGAGCGTTACGGCGCGGACACCGTGCGTCTGTTCATGATGTTTGCTTCTCCAGCCGATATGACGCTGGAATGGCA
GGAATCTGGCGTGGAAGGGGCAAACCGCTTCCTGAAGCGCGTCTGGAAACTGGTCTATGAGCACACCGCGAAAGGCGAGG
TTGCGGCACTGAACGTTGATGCGCTGAGCGAAGATCAGAAAGCGCTGCGTCGCGACGTCCACAAAACCATCGCGAAAGTG
ACCGATGATATCGGCCGCCGTCAGACCTTCAACACCGCGATTGCCGCGATTATGGAGCTGATGAACAAACTGGCGAAAGC
GCCGCAGGAAGGCGAGCAGGATCGCGCCCTGATGCAGGAAGCGCTGCTGGCTGTCGTGCGTATGCTCAACCCGTTCACCC
CACATGCCTGCTTCACGCTGTGGGAAGCGCTGAAAGGCGAAGGCGATATCGATAACGCGCCGTGGCCGGTCGCTGACGAC
AAAGCAATGGTAGAAGACTCTACGTTGGTTGTGGTTCAGGTGAACGGTAAAGTCCGTGGCAAAATCACCGTACCGGTGAA
CGCCACTGAAGAACAGGTTCGTGAACGTGCTGGCCAGGAACATTTGGTCGCAAAATATCTTGATGGCGTTACCGTGCGTA
AAGTGATTTACGTTCCGGGTAAACTCCTCAATTTGGTCGTTGGCTAA

Protein sequence :
MKTGPLAAMQEQYRPEEIESKVQQHWDEKRTFEVTEDESKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVIARYQRMLGKN
VLQPIGWDAFGLPAEGAAVKNNTAPAPWTYDNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKK
TSAVNWCPNDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKTMQRNWIGRSEGVEI
TFDVNGYDNTLTVYTTRPDTFMGATYLAVAAGHPLAQKAAANNPELAAFIDECRNTKVAEADMATMEKKGVDTGFKAIHP
LTGEAIPVWAANFVLMEYGTGAVMAVPGHDQRDYEFATKYGLTIKPVILAADGSEPDLSEQALTEKGVLFNSGEFNGLGF
EDAFNAIADKLAAKGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVLPTPEDQLPVILPEDVVMDGITSPIKADPE
WAKTTVNGQPALRETDTFDTFMESSWYYARYTCPQYNEGMLDPEAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAG
MVNSDEPAKQLLCQGMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSKNNGIDPQV
MVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTAKGEVAALNVDALSEDQKALRRDVHKTIAKV
TDDIGRRQTFNTAIAAIMELMNKLAKAPQEGEQDRALMQEALLAVVRMLNPFTPHACFTLWEALKGEGDIDNAPWPVADD
KAMVEDSTLVVVQVNGKVRGKITVPVNATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLNLVVG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 1e-152 42