Gene Information

Name : CKO_02152 (CKO_02152)
Accession : YP_001453712.1
Strain : Citrobacter koseri ATCC BAA-895
Genome accession: NC_009792
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : -
Position : 1992056 - 1992802 bp
Length : 747 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence :
ATGAGTTTTGTGGTCATTATTCCCGCTCGTTTTTCGTCCACGCGTCTACCCGGTAAGCCTTTACTGGATATCAACGGCAA
ACCGATGATCGTGCATGTTCTGGAACGCGCGCGCGAATCTGGCGCTGAACGCATTATTGTCGCGACGGACCATGAAGATG
TCGCTCGCGCGGTAGAAGCGGCGGGTGGGGAAGTCTGCATGACGCGCGCTGACCATCAGTCCGGGACGGAGCGTCTGGCG
GAAGTCGTCGAAAAATGCGGTTTTAGCGACGATACCGTTATTGTGAACGTGCAGGGCGATGAGCCGATGATCCCGGCGGT
GATTATTCGTCAGGTGGCGGAAAACCTGGCGCAGCGCCAGGTTGGTATGGCAACGCTGGCGGCGCCGATTCACGGTGCTG
AAGAAGCCTTTAATCCTAATGCAGTGAAAGTTGTGCTGGACGCTGAAGGCTATGCGCTTTATTTCTCGCGTGCGACGATC
CCCTGGGATCGCGATCGTTTTGCGAAAAGCCTTGAGACCGTGGGCGACACGTTCCTGCGCCATCTGGGAATTTACGGCTA
TCGCGCCGGGTTTATTCGCCGCTACGTGAACTGGCAGCCCAGCCCACTTGAGCATATTGAGATGCTGGAGCAGCTTCGTG
TGCTGTGGTATGGCGAAAAAATCCATGTTGCCGTCGCCAAAGAAGTCCCGGGAACGGGCGTTGATACAGCCGAAGATCTT
GAGCGCGTTCGCGCCGAAATGCGCTGA

Protein sequence :
MSFVVIIPARFSSTRLPGKPLLDINGKPMIVHVLERARESGAERIIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLA
EVVEKCGFSDDTVIVNVQGDEPMIPAVIIRQVAENLAQRQVGMATLAAPIHGAEEAFNPNAVKVVLDAEGYALYFSRATI
PWDRDRFAKSLETVGDTFLRHLGIYGYRAGFIRRYVNWQPSPLEHIEMLEQLRVLWYGEKIHVAVAKEVPGTGVDTAEDL
ERVRAEMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-34 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 8e-34 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 3e-34 44