Gene Information

Name : hsdM (SGO_0560)
Accession : YP_001449876.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Unknown
Product : type I restriction-modification system, M subunit
Function : -
COG functional category : V : Defense mechanisms
COG ID : COG0286
EC number : 2.1.1.72
Position : 605957 - 607564 bp
Length : 1608 bp
Strand : +
Note : identified by match to protein family HMM PF02384; match to protein family HMM TIGR00497

DNA sequence :
ATGATACTAGAAACAACACAAACCTCCCAGTCGCTCTACCAAGCCCTGTGGAACTCGGCGGATGTGCTCCGCTCTAAGAT
GGATGCCAATGACTATAAGTCTTATCTCTTGGGGATGATCTTTTACAAGTATCTCTCAGATAAGTTGCTCTTCTTCGTGG
CAGAGACCATGGAGGAGGAGACAGAGAGCTTAGATGAAGCCTTGGCTCTTTACCGAACCTACTATGAGGATCCAGACTCT
CAAGAGGATCTGATCACCGTCATCACCGATGAGCTCAACTATGTCATCAAGCCAGACTTGACCTTTACGGCCTTGGTGGA
TCGGGTCAATGAAGGCACCTTCCAACTGGAAGATCTAGCTCAGGGCTTCCGAGATATTGAGCAATGTGATGAACTCTATG
AAAACCTCTTTGAGGACATTGATCTTTACTCTAAGAAGCTAGGAGCAACTCCTCAAAAGCAAAACCAGCTAGTAGCTGCG
GTCATGAAAGAGCTAGCAGTCCTGGAAGTAGCAGGTCATGCGGGAGATATGCTGGGCGATGCCTATGAGTATCTGATCGG
TCAGTTTGCGACCGACTCGGGTAAGAAGGCAGGAGAGTTCTATACGCCGCAGCCTGTGGCCAAGCTCATGACCCAGATTG
CCTTTTTAGGGCGTGAAGACGAGCAGGGCTTTACACTCTACGATGCCACCATGGGATCAGGCTCCCTCTTGCTCAATGCT
AAGAAGTATTCTCATCAACCTCAAACAGTCCAATACTTCGGTCAGGAGCTCAATACTTCGACCTATAATCTAGCTCGGAT
GAACATGATCCTCCACGGGGTTCCTGTTGAAAACCAGTTCTTGCACAATGCCGATACGCTGGATGAAGACTGGCCGACAC
AAGAGCCGACCAACTTTGACGGTGTTCTCATGAATCCTCCTTACTCAGCCAAGTGGTCTGCTAGCTCTGGCTTCCTGAAT
GATCCTCGTTTCTCTCCTTTTGGGAAACTCGCGCCTCAGTCCAAAGCTGACTTTGCTTTTCTCTTGCATGGTTATTACCA
CCTCAAGCAGGACAAGGGAGTCATGGCTATCGTCCTACCTCACGGGGTCCTCTTCCGTGGTAACGCCGAAGGAACCATTC
GCAAGGCCTTGCTGGAAGAAGGGGCCATTGATACGGTGATCGGTCTACCTGCTAATATCTTCTTTAATACCAGCATTCCG
ACCACGGTTATCATTCTCAAAAAGAATCGCACCAATCGGGACGTTTACTTTATCGATGCTTCTAAGGAGTTTGATAAGGG
GAAAAACCAGAATATCATGACAGATGCTCATATCGAGAAGATTCTGGAAGCCTACAAGTCTCGTGAGGAGATGGACAAGT
TTGCCCATCTGGCAAGCTATGAAGAAATTGTTGAAAATGACTATAACCTCAATATTCCTCGCTATGTAGATACCTTTGAG
GAAGAAGAAGTAGAGCCATTGACAGAAATCGTCAGCAAGATTAACGAGACAAATAAAGCAATCGAAAGCCAAACAGCTTC
GCTACTCGAAATGCTTAATCAACTCCACGGCACAACACCAGAAGCAGATGCTGAGCTCAAACAGTTTTTGAAGGAGTTTA
AAGGGTGA

Protein sequence :
MILETTQTSQSLYQALWNSADVLRSKMDANDYKSYLLGMIFYKYLSDKLLFFVAETMEEETESLDEALALYRTYYEDPDS
QEDLITVITDELNYVIKPDLTFTALVDRVNEGTFQLEDLAQGFRDIEQCDELYENLFEDIDLYSKKLGATPQKQNQLVAA
VMKELAVLEVAGHAGDMLGDAYEYLIGQFATDSGKKAGEFYTPQPVAKLMTQIAFLGREDEQGFTLYDATMGSGSLLLNA
KKYSHQPQTVQYFGQELNTSTYNLARMNMILHGVPVENQFLHNADTLDEDWPTQEPTNFDGVLMNPPYSAKWSASSGFLN
DPRFSPFGKLAPQSKADFAFLLHGYYHLKQDKGVMAIVLPHGVLFRGNAEGTIRKALLEEGAIDTVIGLPANIFFNTSIP
TTVIILKKNRTNRDVYFIDASKEFDKGKNQNIMTDAHIEKILEAYKSREEMDKFAHLASYEEIVENDYNLNIPRYVDTFE
EEEVEPLTEIVSKINETNKAIESQTASLLEMLNQLHGTTPEADAELKQFLKEFKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SSP0053 YP_300143.1 type I restriction-modification system methyltransferase subunit Not tested SCC15305cap Protein 1e-100 48
SAKOR_00415 YP_008490599.1 Type I restriction-modification system methylation subunit Not tested vSa¥á Protein 1e-98 46
hsdM NP_646568.1 hypothetical protein Not tested vSa¥â Protein 4e-98 46
hsdM1 YP_185366.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 1e-98 46
SAV1808 NP_372332.1 type I restriction enzyme EcoR124II M protein Not tested vSa¥â Protein 4e-98 46
hsdM YP_001331432.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥á Protein 1e-98 46
SA1626 NP_374915.1 hypothetical protein Not tested vSa¥â Protein 4e-98 46
SAR1899 YP_041281.1 type I restriction modification system modification protein Not tested vSa¥â Protein 2e-97 46
hsdM YP_493119.1 type I restriction-modification system, M subunit Not tested vSa¥á Protein 1e-98 46
hsdM NP_645209.1 type I site-specific deoxyribonuclease LldI chain hsdM Not tested vSa¥á Protein 3e-98 46
hsdM NP_373642.1 type I site-specific deoxyribonuclease LldI subunit HsdM Not tested vSa¥á Protein 3e-98 46
SAMSHR1132_16570 YP_005326167.1 restriction-modification system, M subunit Not tested vSa¥â Protein 8e-98 46
SAS0394 YP_042520.1 restriction enzyme modification protein Not tested vSa¥á Protein 2e-98 46
SAR0433 YP_039884.1 type I restriction enzyme modification protein Not tested vSa¥á Protein 6e-98 46
hsdM2 YP_186690.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 2e-98 46
SAMSHR1132_03780 YP_005324900.1 putative type I restriction enzyme modification protein Not tested vSa¥á Protein 6e-98 46
ORF6 BAC22943.1 - Not tested etd PI Protein 2e-98 46
SAS1732 YP_043848.1 type I restriction enzyme modification protein Not tested vSa¥â Protein 4e-98 46
hsdM YP_001332734.1 type I restriction-modification system, methyltransferase subunit Not tested vSa¥â Protein 1e-98 46
hsdM YP_494443.1 type I restriction-modification system, M subunit Not tested vSa¥â Protein 1e-98 46
SAKOR_01757 YP_008491945.1 Type I restriction-modification system methylation subunit Not tested vSa¥â Protein 2e-98 46
hsdM NP_370955.1 type I site-specific deoxyribonuclease LldI chain Not tested vSa¥á Protein 1e-97 45