Gene Information

Name : secA (SGO_0415)
Accession : YP_001449731.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Unknown
Product : preprotein translocase subunit SecA
Function : -
COG functional category : U : Intracellular trafficking, secretion and vesicular transport
COG ID : COG0653
EC number : -
Position : 458246 - 460762 bp
Length : 2517 bp
Strand : +
Note : functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis ap

DNA sequence :
ATGGCAAATATTTTAAGAACAATTATCGAAAATGATAAAGGTGAATTAAGAAAATTAGAGAAAATGGCAAATAAGGTCAT
TGCTTATAGTGACCAGATGGCTGCCTTGTCCGATGAGGAATTAAAGGCTAAAACAGATGAATTTAAACAACGTTATCAGA
ACGGTGAAAGTTTAGATGACTTGCTTTATGAAGCCTTCGCAGTTGTCCGTGAGGGTGCGAAACGTGTTCTTGGCCTCTAT
CCTTATCCAGTACAGATTATGGGGGGGATTGTTCTCCATCATGGTGACGTACCAGAGATGCGTACAGGTGAAGGTAAAAC
TCTTACTGCGACCATGCCTGTTTACTTGAATGCGTTGGCAGGAGAAGGAGTTCACGTTGTAACGGTCAATGAATATCTGA
CAGAACGTGATGCGACCGAAATGGGTGAACTGTACTCTTGGTTAGGGCTTTCAGTTGGTATTAACTTGGCGGCTAAATCT
CCAGCTGAGAAGAGAGAAGCCTATGCTTGTGACATCACCTACTCAACGAACTCAGAAATTGGCTTTGATTACCTCCGTGA
TAACATGGTGGTTCGTGCTGAAAACATGGTTCAGCGCCCACTTAACTATGCCTTGGTCGATGAGGTGGATTCCATTCTGA
TCGATGAAGCTAGAACCCCTCTGATTGTTTCTGGACCAGTTTCATCTGAAACTAATCAGCTTTACCACATGGCGGATAGC
TTCGTTAAGAGTCTTAACAAGGATGATTACATCATAGATGTGCCATCAAAAACAATCGGCTTGTCTGACTCTGGAATTGA
CAAGGCAGAAAGCTATTTCAAATTAGATAATCTCTATGATATTGAAAATGTGGCATTGACTCACTTCATTGATAATGCCT
TGCGTGCTAACTATATCATGATTTTGGACATCGATTATGTGGTTAGCGAAGAACAAGAAATTCTGATCGTTGACCAGTTC
ACCGGTCGTACCATGGAAGGACGTCGCTATTCTGACGGACTTCACCAGGCCATTGAAGCTAAAGAAGGTGTTCCGGTTCA
AGATGAAACCAAGACATCTGCTTCTATTACCTACCAAAACCTCTTCCGTATGTATAAAAAACTGTCTGGAATGACTGGTA
CAGCTAAGACTGAGGAAGAAGAATTCCGCGAAACTTATAATATCCGTGTTATCCCAATTCCAACTAACCGCCCAATTGCT
CGTATTGACCATGAGGATTTACTTTACCCTAGTTTAGAATCTAAATTTAAGGCAGTTGTAGAAGACGTGAAAGAACGCCA
TCTTAAAGGACAGCCTGTTCTGGTCGGTACAGTTGCAGTTGAAACCAGTGACTATCTTTCTAAAAAGCTGGTTGCAGCAG
GAATTCCTCATGAGGTATTGAATGCTAAGAACCACTATCGTGAAGCGCAAATCATTATGAATGCTGGCCAACGCGGTGCA
GTTACAATTGCAACCAATATGGCTGGTCGTGGTACCGATATTAAGCTTGGAGAAGGTGTGCGCGAATTGGGCGGTCTCTG
TGTGATTGGTACAGAACGCCATGAAAGCCGTCGTATTGACAATCAGTTACGTGGACGTTCTGGTCGTCAGGGAGATCCAG
GTGAATCTCAATTCTATCTATCTCTTGAAGATGAGCTGATGCGTCGTTTTGGTTCTGAGAGAATCAAAGCTGTCTTGGAT
CGTTTCAAACTGAGCGAAGAAGAGTCTGTCATTAAGTCTAAGATGTTTACGCGCCAAGTTGAAGCGGCTCAAAAACGGGT
TGAAGGAAATAACTATGATACTCGTAAGCAAGTCCTTCAGTATGACGATGTGATGCGTGAACAACGTGAAATTATCTACG
CTGAACGTCATGATGTTATCACAGCTAATCGGGATTTGGCTCCAGAGATTCACGCTATGATCAAACGGACTATTGATCGT
TTTGTTGATGGAAATAGCAGAGCTCCTCAAGAAGAAAAATTGGATTCAATTTTGTACTTTGCTAAGTATAACTTGGTTCC
GGAAGAGTCAATTTCATTGAGCGATCTTCAAGGTTTATCTGATGAGGAAATCAAGGCTAGCTTATACGAACGTGCTTTGG
AAGTCTACAATAGTCAAATTGCTAAACTTCGTGATGAAGAAGCTGTTCGAGAATTCCAAAAAGTATTGATTCTACGTGTT
GTAGATAACAAGTGGACAGATCACATTGATGCATTGGATCAGCTTCGTAATGCTGTAGGTCTTCGAGGCTATGCTCAAAA
TAATCCTGTTGTTGAATACCAATCTGAAAGTTTCAGAATGTTTAACGATATGATTGGTTCGATTGAGTTTGATGTGACCC
GTCTTATGATGAAAGCACAAATTCATGAGCAAGAGCGTCCTCGTACAGAGCACAATATTGTAACAACAGCAACGCGCAAT
ATCTCAGCGCAAGAATCAGACCTGCCAGCAGACGTTGATTTGGCAAAGGTTGGCCGGAATGAACTATGCCCATGTGGCTC
AGGTAAGAAGTTTAAAAATTGCCACGGCCGTCGTTAA

Protein sequence :
MANILRTIIENDKGELRKLEKMANKVIAYSDQMAALSDEELKAKTDEFKQRYQNGESLDDLLYEAFAVVREGAKRVLGLY
PYPVQIMGGIVLHHGDVPEMRTGEGKTLTATMPVYLNALAGEGVHVVTVNEYLTERDATEMGELYSWLGLSVGINLAAKS
PAEKREAYACDITYSTNSEIGFDYLRDNMVVRAENMVQRPLNYALVDEVDSILIDEARTPLIVSGPVSSETNQLYHMADS
FVKSLNKDDYIIDVPSKTIGLSDSGIDKAESYFKLDNLYDIENVALTHFIDNALRANYIMILDIDYVVSEEQEILIVDQF
TGRTMEGRRYSDGLHQAIEAKEGVPVQDETKTSASITYQNLFRMYKKLSGMTGTAKTEEEEFRETYNIRVIPIPTNRPIA
RIDHEDLLYPSLESKFKAVVEDVKERHLKGQPVLVGTVAVETSDYLSKKLVAAGIPHEVLNAKNHYREAQIIMNAGQRGA
VTIATNMAGRGTDIKLGEGVRELGGLCVIGTERHESRRIDNQLRGRSGRQGDPGESQFYLSLEDELMRRFGSERIKAVLD
RFKLSEEESVIKSKMFTRQVEAAQKRVEGNNYDTRKQVLQYDDVMREQREIIYAERHDVITANRDLAPEIHAMIKRTIDR
FVDGNSRAPQEEKLDSILYFAKYNLVPEESISLSDLQGLSDEEIKASLYERALEVYNSQIAKLRDEEAVREFQKVLILRV
VDNKWTDHIDALDQLRNAVGLRGYAQNNPVVEYQSESFRMFNDMIGSIEFDVTRLMMKAQIHEQERPRTEHNIVTTATRN
ISAQESDLPADVDLAKVGRNELCPCGSGKKFKNCHGRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
secA2 YP_006310687.1 preprotein translocase subunit SecA2 Not tested FWisland_3 Protein 8e-146 42