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Name : merA (SGO_0368) Accession : YP_001449687.1 Strain : Streptococcus gordonii Challis Genome accession: NC_009785 Putative virulence/resistance : Resistance Product : mercury(II) reductase Function : - COG functional category : C : Energy production and conversion COG ID : COG1249 EC number : 1.16.1.1 Position : 398290 - 400185 bp Length : 1896 bp Strand : + Note : identified by match to protein family HMM PF00070; match to protein family HMM PF00403; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR02053 DNA sequence : ATGAATAAATTTAAGGTAAACATTTCAGGAATGACTTGTACGGGTTGTGAAAAACACGTAGAATCAGCACTTGAAAAGAT AGGTGCTAAAAATATTGAGTCTAGTTATCGTCGTGGTGAAGCAGTATTTGAACTGTCCGATGATATTGAGGTTGAAAGTG CAATAAAGGCGATTGCTGACGCAAATTATCACCCGGGCGAAGCAGAAGAATTTCAATCGGAACAAAAGACGAATTTATTG AAAAAATATCGGCTAAACGTTGAAGGAATGACCTGCACTGGTTGTGAAGAACATATTGCGGTTGCTCTTGAAAATGCAGG TGCAAAAGGGATTGAAGTAGACTTTCGTCGCGGAGAAGCACTGTTTGAACTACCGTATGATGTAGACATTGATATCGCGA AAACAGCGATTACTGACGCACAATATCAACCGGGCGAAGCAGAAGAAATACAAGTGCAATCGGAAAAAAGGACAGATGTA AGTTTAAATGATGAAGGTAACTATGATTATGATTACATCATCATCGGTTCTGGTGGAGCTGCCTTTTCATCTGCCATTGA AGCCGTTACTTTGAACGCAAAAGTGGCTATGATTGAGCGTGGAACGGTGGGTGGAACTTGCGTTAATGTCGGATGCGTTC CTTCTAAGACCTTATTAAGAGCAGGGGAAATCAATCATCTAGCAAAAAATAATCCATTTGTGGGATTACACACTTCGGCT TCAAATGTTGATTTAGCGCCATTAGTAAAACAAAAGAATGATTTAGTAACCGAGATGCGAAATGAAAAATATGTGAATTT AATTGATGATTATGGTTTTGAATTAATAAAAGGTGAAGCAAAATTCGTAAATGAAAATACAGTTGAAGTAAATGACAATC AAATCACAGCCAAAAGATTTTTAATAGCTACAGGTGCTTCTTCAACTGCACCTAATATTCCCGGATTAGATGAAGTAGAT TATTTAACAAGCACTAGCTTATTGGAATTAAAGAAGGTTCCAAATCGTCTTACCGTAATTGGTTCAGGATATATCGGCAT GGAATTAGGACAACTATTTCATAACCTCGGGTCAGAAGTCACTTTGATTCAAAGAAGCGAGCGTCTATTAAAAGAATACG ATCCTGAAATTTCAGAAGCCATTACTAAGGCCTTAACAGAACAGGGAATTAATTTAGTAACAGGTGCAACCTATGAACGA GTTGAGCAAGATGGAGACATTAAAAAAGTTCATGTTGAGATAAATGGTAAAAAGCGAATTATTGAAGCAGAACAATTGCT AATTGCCACTGGAAGAAAACCAAATACAGAATCATTAAACTTACATGCAGCAGGCGTTGAAGTTGGTTCCCGTGGTGAAA TTGTCATTGATGATTATCTTAAAACGACCAATTCCCGAATTTATTCAGCTGGAGATGTCACTCTCGGTCCCCAATTTGTT TATGTAGCTGCTTATGAAGGTGGACTTGCTGCTCGTAATGCAATCGGAGGACTAAATCAAAAGGTCAATTTAGAAGTGGT TCCAGGCGTTACGTTTACTTCTCCATCGATTGCAACGGTTGGTTTAACGGAGCAACAGGCAAAAGAAAAAGGATATGAAG TGAAAACATCGGTATTGCCGTTGGATGCTGTTCCAAGAGCGCTCGTTAATCGGGAAACAACAGGTGTTTTCAAATTAGTG GCAGACGCGAAAACATTGAAAGTGTTAGGGGCGCATGTAGTGGCAGAAAACGCAGGAGACGTAATTTATGCAGCAACATT AGCTGTGAAATTCGGTTTAACTGTTGGAGATCTGAGAGAAACGATGGCTCCATATCTAACAATGGCAGAAGGATTGAAGC TGGCTGTCCTAACTTTTGATAAAGATGTTTCGAAATTATCTTGCTGTGCAGGCTAA Protein sequence : MNKFKVNISGMTCTGCEKHVESALEKIGAKNIESSYRRGEAVFELSDDIEVESAIKAIADANYHPGEAEEFQSEQKTNLL KKYRLNVEGMTCTGCEEHIAVALENAGAKGIEVDFRRGEALFELPYDVDIDIAKTAITDAQYQPGEAEEIQVQSEKRTDV SLNDEGNYDYDYIIIGSGGAAFSSAIEAVTLNAKVAMIERGTVGGTCVNVGCVPSKTLLRAGEINHLAKNNPFVGLHTSA SNVDLAPLVKQKNDLVTEMRNEKYVNLIDDYGFELIKGEAKFVNENTVEVNDNQITAKRFLIATGASSTAPNIPGLDEVD YLTSTSLLELKKVPNRLTVIGSGYIGMELGQLFHNLGSEVTLIQRSERLLKEYDPEISEAITKALTEQGINLVTGATYER VEQDGDIKKVHVEINGKKRIIEAEQLLIATGRKPNTESLNLHAAGVEVGSRGEIVIDDYLKTTNSRIYSAGDVTLGPQFV YVAAYEGGLAARNAIGGLNQKVNLEVVPGVTFTSPSIATVGLTEQQAKEKGYEVKTSVLPLDAVPRALVNRETTGVFKLV ADAKTLKVLGAHVVAENAGDVIYAATLAVKFGLTVGDLRETMAPYLTMAEGLKLAVLTFDKDVSKLSCCAG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| merA | BAB47642.1 | mercuric reductase | Not tested | Type-III SCCmec | Protein | 0.0 | 68 |
| SE0085 | NP_763640.1 | dihydrolipoamide dehydrogenase | Not tested | SCCpbp4 | Protein | 0.0 | 68 |
| merA | AAN62178.1 | mercuric (Hg(II)) reductase | Not tested | PAGI-2(C) | Protein | 2e-80 | 43 |
| merA | AGK07079.1 | MerA | Not tested | SGI1 | Protein | 2e-81 | 41 |
| merA | ACN81005.1 | MerA Hg(II) mercuric ion reductase | Not tested | AbaR5 | Protein | 3e-79 | 41 |
| merA | ABQ57371.1 | MerA | Not tested | SGI1 | Protein | 2e-81 | 41 |
| merA | AGK07021.1 | MerA | Not tested | SGI1 | Protein | 2e-81 | 41 |
| merA | CAJ77060.1 | Mercuric ion reductase | Not tested | AbaR1 | Protein | 1e-79 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| merA | YP_001449687.1 | mercury(II) reductase | BAC0224 | Protein | 0.0 | 96 |
| merA | YP_001449687.1 | mercury(II) reductase | BAC0651 | Protein | 0.0 | 68 |
| merA | YP_001449687.1 | mercury(II) reductase | BAC0653 | Protein | 3e-78 | 42 |
| merA | YP_001449687.1 | mercury(II) reductase | BAC0652 | Protein | 7e-78 | 41 |
