Gene Information

Name : clpB (SGO_1998)
Accession : YP_001451248.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp proteinase, ATP-binding chain
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 2049395 - 2051824 bp
Length : 2430 bp
Strand : -
Note : identified by match to protein family HMM PF00004; match to protein family HMM PF02861; match to protein family HMM PF07724; match to protein family HMM PF07728

DNA sequence :
ATGAAATATTCAAAAGCCTTGATTGTTAGTATAGAAGAAGCCCAGCAACTGGCTAGTCATTTTGAATCTGAGTATTTAGA
GTCATGGCATCTCTTGATTGCTTTTTCTAATTATCCGTACAGCGTAGCAGGCTCAGTTTTAAACGATTATCCGCTAGAAA
TTGATCATTTTGAGGATGCTGCTTACCATGTGGTAGGGAAATCTTATCAGAAGGAAGGGCGATTTAGTATCCTGCCTTTT
TCTCATCGCTTGACGACTCTTTTTAAGGAGGCAAAAGCTATAGCCGAAGCTACTCACGCAAAGGAAGTCGGAACTGAACA
CATCTTATACGCTATCATCAGCGATAGAGGTACCCTAGCAACTCGTATTTTGGAATTTGTCGGCTTTAGTTATGAAGACA
AAGAAGGAGTCTTGCGTATTAATGATTTGCGAAGAAATCTGGAACAAAAGTCTGGCTGGACTAAGAATGATTTAAAAGCA
ATCCGCAGTCTTCATAAAGGTTTTAATCAAGCCAAGCAAAACATGGCAAACATGATGGGGATGCCACCTACTCAGAGTGG
TGGTCTAGAAGATTACACACGAGACTTGACGGAATTAGCTCGTTCAGGTCAGCTAGAGCCTGTTGTTGGTCGAGATCAGG
AAATCTCTCGGATGATTCAGGTTCTCAGTCGCAAGACGAAGAATAACCCTGTCTTGGTTGGGGATGCTGGAGTTGGTAAA
ACTGCTCTAGCTCTCGGTTTGGCCCAGCGTGTAGCTTCTGGTCAAGTTCCACACGAACTAGCCAAAATGCGGGTTTTAGA
GCTTGATTTAATGAATGTAGTCGCAGGGACTCGTTTCCGTGGGGATTTTGAAGAGCGTATGAACAATATCATCGATGATA
TTGAGAAAGATGGTAAGGTCATTCTCTTTATCGATGAGCTTCATACGATTATGGGATCTGGTAGCGGTATTGACTCTACG
ATGGATGCTGCGAATATCCTTAAACCTGCTCTGGCTCGCGGAACACTGCGTACGATAGGAGCTACAACTCAAGAAGAATA
CCAAAAGCATATTGAAAAAGACGCTGCTCTATCTCGGCGCTTTGCTAAGATCAGTATTGAAGAACCAAGTGTGGCTGACA
GCATTGCTATCCTTAAGGGCCTAAAAGAAAACTATGAAGCCCATCATAAGGTAACGATTACAGATCAAGCCATTGAAACA
GCAGTAAAATATGCCCACCGTTATTTGACAAGTAAGCATCTGCCTGATTCAGCAATTGATCTGTTAGATGAAGCGAGTGC
CACAGTACGTAACAATGGTCCTCAGAGTCATGCACAAGAGGATTTGAGTCCAGCAGATCGAGCAATTATAGCTGGTCAGT
TCAATAAACTTAGTCGCTTGATCGAGAAAGAAAATCAACCTCTGTTAAGTGATTTAAGAGTAGAGGAAGCAGATATTCTG
ACAACCCTAAGTCGGCTGTCTGGTATTCCAGTTCAAAAATTGACCCAGACAGATGCTAAGAAGTATTTGCACTTAGAAGA
AGAATTGCATAAGCGGGTGATTGGTCAAGATGAAGCTATCTCAGCTATTAGTCGTGCAATCCGTCGTAACCAGTCAGGTA
TTCGAGCGAATAAGCGACCGATTGGTTCCTTTATGTTCTTGGGACCAACTGGAGTTGGTAAGACCGAGTTGGCTAAGGCT
TTGGCAGAAACCCTCTTTGACGACGAATCAGCTCTCATTCGTTTTGATATGAGTGAATACATGGAGAAATTTGCTGCTAG
CCGTCTCAATGGAGCGCCTCCAGGCTACGTCGGCTATGAAGAAGGAGGCGAATTAACAGAGAAAGTTCGCAACCGACCAT
ATTCCGTCCTCTTATTTGATGAAGTGGAAAAAGCTCATCCAGATATTTTCAATGTCCTTCTGCAGGTTTTAGATGATGGT
GTATTAACTGATAGTAAGGGACGAAAGATTGATTTTTCAAATACGATTATTATCATGACCAGTAACCTAGGTGCAACCAG
TCTGCGTGATGATAAGACAGTTGGCTTTGGGGCTCGCGACATCCGTTTAGACCATGCAAATATGGAAAAACGAATGTTAG
AAGAGCTCAAAAAGACATACCGTCCAGAATTTATTAACCGGATTGATGAAAAAGTCGTCTTCCATAGCTTGTCTGCTGAC
CATATGCAGGAGGTTGTAAAAGTGATGATTAAGCCTCTGGTTGCCAGTCTAGCTGAAAAGAATATCCAACTAAAATTCCA
AGCTAGTGCCTTGAAACTACTAGCTAAAGAAGGCTATGATGTAGAAATGGGGGCTAGACCTCTTCGTAGGACTCTGCAAA
CCAAAGTTGAAGACAAACTAGCAGAACTGCTATTGACAGGTGATTTACAAGCAGGCCAGACCTTGAAGGTGGGAGTTAAG
GCAGGTCAGTTGAAGTTTGATATAGCCTAA

Protein sequence :
MKYSKALIVSIEEAQQLASHFESEYLESWHLLIAFSNYPYSVAGSVLNDYPLEIDHFEDAAYHVVGKSYQKEGRFSILPF
SHRLTTLFKEAKAIAEATHAKEVGTEHILYAIISDRGTLATRILEFVGFSYEDKEGVLRINDLRRNLEQKSGWTKNDLKA
IRSLHKGFNQAKQNMANMMGMPPTQSGGLEDYTRDLTELARSGQLEPVVGRDQEISRMIQVLSRKTKNNPVLVGDAGVGK
TALALGLAQRVASGQVPHELAKMRVLELDLMNVVAGTRFRGDFEERMNNIIDDIEKDGKVILFIDELHTIMGSGSGIDST
MDAANILKPALARGTLRTIGATTQEEYQKHIEKDAALSRRFAKISIEEPSVADSIAILKGLKENYEAHHKVTITDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVRNNGPQSHAQEDLSPADRAIIAGQFNKLSRLIEKENQPLLSDLRVEEADIL
TTLSRLSGIPVQKLTQTDAKKYLHLEEELHKRVIGQDEAISAISRAIRRNQSGIRANKRPIGSFMFLGPTGVGKTELAKA
LAETLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
VLTDSKGRKIDFSNTIIIMTSNLGATSLRDDKTVGFGARDIRLDHANMEKRMLEELKKTYRPEFINRIDEKVVFHSLSAD
HMQEVVKVMIKPLVASLAEKNIQLKFQASALKLLAKEGYDVEMGARPLRRTLQTKVEDKLAELLLTGDLQAGQTLKVGVK
AGQLKFDIA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 2e-146 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB YP_001451248.1 ATP-dependent Clp proteinase, ATP-binding chain VFG0079 Protein 7e-163 52
clpB YP_001451248.1 ATP-dependent Clp proteinase, ATP-binding chain VFG0080 Protein 4e-122 45