Gene Information

Name : leuS (SGO_1784)
Accession : YP_001451053.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1855920 - 1858421 bp
Length : 2502 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAGTACTTACAATCATAGAGAAATCGAGCCCAAATGGCAGAAATACTGGGCAGAACACCACACATTTAAGACAGGTAC
GGATAAGGACAAGCCTAACTTTTATGCGCTGGACATGTTTCCTTACCCATCAGGAGCGGGGCTCCATGTAGGGCATCCGG
AGGGCTATACGGCGACAGATATCCTCAGCCGCTACAAGCGTGCGCAAGGCTACAATGTCCTCCACCCTATGGGCTGGGAC
GCCTTTGGTCTTCCAGCTGAGCAGTATGCCATGGATACAGGCAATGATCCAGCTGACTTTACAGCAGAAAATATTGCCAA
CTTCAAGCGTCAAATCAACGCTCTTGGTTTCTCCTATGACTGGGACCGGGAGGTCAATACTACCGACCCTAACTACTACA
AGTGGACTCAGTGGATTTTCACCAAACTTTACGAAAAAGGTCTGGCTTATGAAGCAGAAGTACCAGTAAACTGGGTGGAA
GAGCTGGGAACGGCTATTGCCAATGAGGAAGTTCTGCCAGACGGCACTTCTGAGCGCGGTGGTTATCCAGTTGTCCGCAA
GCCTATGCGTCAGTGGATGCTGAAAATCACAGCCTATGCAGAACGTTTGCTCAATGACTTGGAGGAGCTGGATTGGCCAG
AGTCTATCAAGGATATGCAACGCAACTGGATCGGTAAATCAACCGGTGCCAATGTAACCTTCAAGATTAAGGACACAGAC
AAGGACTTCACCGTCTTTACCACTCGTCCGGACACCCTTTTTGGTGCGACCTATGCTGTTTTGGCTCCAGAGCATGCTCT
TGTTGATGTCATTACAAGTGCCGAACAAGCCCAAGCAGTTGCAGACTACAAACATGCAGCCAGCCTCAAATCCGACCTGG
CTCGGACTGATTTGGCTAAGGAGAAGACCGGTGTCTGGACAGGAGCTTATGCTATCAATCCTGTCAATGGCAAGGAAATC
CCCATCTGGATTGCCGACTATGTGCTTGCTAGCTACGGAACAGGGGCTATCATGGCTGTTCCTGCCCACGATGAGCGCGA
CTGGGAGTTTGCTAAGCAGTTTGACTTGGAGATTATTCCGGTTCTAGAAGGTGGCAATGTTGCTGACGCTGCTTATACAG
AAGACGGTCCGCATATTAACTCTGGCTTCCTAGATGGCTTGGACAAGGCTGCCGCTATTGAGAAGATGGTTGCTTGGCTG
GAAAAAGAAGGTGTCGGAAATGAAAAAGTAACCTATCGTCTGCGCGACTGGCTCTTTAGCCGTCAGCGCTACTGGGGTGA
GCCGATTCCAATCATTCATTGGGAAGATGGGACTTCAACAGCAGTTCCAGAAAGTGAACTGCCACTTGTCCTGCCGGTAA
CCAAGGATATCCGTCCTTCTGGTACTGGTGAAAGTCCTCTGGCTAATCTGACTGACTGGCTGGAAGTCACTCGAGAAGAC
GGTGTCAAAGGACGCCGTGAAACCAACACCATGCCTCAATGGGCAGGTTCTAGCTGGTATTACCTGCGTTACATTGACCC
GCACAATAATGAGAAGTTAGCAGACGAAGACCTGCTCAAGGCCTGGCTGCCAGTTGATATTTACATCGGTGGTGCAGAGC
ATGCTGTACTTCACCTTCTCTACGCTCGCTTCTGGCACAAGTTCCTCTATGATCTTGGAGTGGTTCCGACCAAAGAGCCT
TTCCAAAAACTCTTTAACCAAGGGATGATTCTGGGGACTAGCTATCGTGATCACCGTGGAGCACTTGTGGCGACTGACAA
GGTGGAAAAACGCGATGGTTCTTTCTTCAACATTGAAACGGGAGAAGAATTAGAGCAAGCGCCTGCTAAGATGTCTAAGT
CTTTGAAGAATGTGGTCAACCCAGACGATGTAGTAGAGCAATATGGTGCCGATACGCTTCGTGTCTATGAAATGTTCATG
GGGCCGCTGGATGCATCTATCGCTTGGAGCGAGGAAGGTCTGGAAGGCAGCCGTAAGTTCCTAGATCGGGTCTATCGTCT
TCTTAACACTAAGGAGCTGGTCACTGAAAATAGCGGAGCTCTCGACAAGGTCTACCATGAAACAGTCAAGTCTGTTACCG
AGCAGCTTGAGGAGCTCAAGTTTAACACAGCCATTGCCCAACTCATGATCTTTGTCAATGCAGCCAACAAGGAAGAAAAA
CTCTATGTCGAATATGCCAAAGGTTTCATCCAATTGCTGGCGCCATTTGCTCCGCACTTGGCCGAAGAACTCTGGCAGGC
AGTAGCTCAAACAGACGAGAGCATTTCCTATGTAGCTTGGCCAACTTATGACGAAAGCAAGCTGGTCGAGGCAGAGGTTG
AAATCGTAGTTCAAATCAAGGGCAAAGTTCGTGCTAAGCTTGTTGTAGCTAAAGATCTGAGCCGTGAAGAATTGCAGGAA
ATCGCTCTGGCAGATGAGAAAATCAAGTCTGAAATCGCCGATAAAGAAGTCGTGAAAGTGATTAGTGTACCGAATAAACT
TGTTAATATCGTTGTGAAATAA

Protein sequence :
MSTYNHREIEPKWQKYWAEHHTFKTGTDKDKPNFYALDMFPYPSGAGLHVGHPEGYTATDILSRYKRAQGYNVLHPMGWD
AFGLPAEQYAMDTGNDPADFTAENIANFKRQINALGFSYDWDREVNTTDPNYYKWTQWIFTKLYEKGLAYEAEVPVNWVE
ELGTAIANEEVLPDGTSERGGYPVVRKPMRQWMLKITAYAERLLNDLEELDWPESIKDMQRNWIGKSTGANVTFKIKDTD
KDFTVFTTRPDTLFGATYAVLAPEHALVDVITSAEQAQAVADYKHAASLKSDLARTDLAKEKTGVWTGAYAINPVNGKEI
PIWIADYVLASYGTGAIMAVPAHDERDWEFAKQFDLEIIPVLEGGNVADAAYTEDGPHINSGFLDGLDKAAAIEKMVAWL
EKEGVGNEKVTYRLRDWLFSRQRYWGEPIPIIHWEDGTSTAVPESELPLVLPVTKDIRPSGTGESPLANLTDWLEVTRED
GVKGRRETNTMPQWAGSSWYYLRYIDPHNNEKLADEDLLKAWLPVDIYIGGAEHAVLHLLYARFWHKFLYDLGVVPTKEP
FQKLFNQGMILGTSYRDHRGALVATDKVEKRDGSFFNIETGEELEQAPAKMSKSLKNVVNPDDVVEQYGADTLRVYEMFM
GPLDASIAWSEEGLEGSRKFLDRVYRLLNTKELVTENSGALDKVYHETVKSVTEQLEELKFNTAIAQLMIFVNAANKEEK
LYVEYAKGFIQLLAPFAPHLAEELWQAVAQTDESISYVAWPTYDESKLVEAEVEIVVQIKGKVRAKLVVAKDLSREELQE
IALADEKIKSEIADKEVVKVISVPNKLVNIVVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 0.0 90