Gene Information

Name : nrdE (SGO_1558)
Accession : YP_001450837.1
Strain : Streptococcus gordonii Challis
Genome accession: NC_009785
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 1611969 - 1614128 bp
Length : 2160 bp
Strand : +
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
ATGGGTTTAAAACACTTAGAAGACGTTACTTACTTCCGTCTTAATAATGAAATTAACCGTCCTGTCAACGGTCAAATCAT
GCTTCATAAAGACCAAGAAGCATTGGAAGCTTTCTTTAAAGAAAACGTTGAGCCGAATACTAAACAATTTTCTTCAATTA
CAGAAAAAATTAAATATTTAATAGAAGAAAACTATCTAGAAAAAGAATTTATTCAGCTTTATTCTCCTGAGTACATCGAA
GAGCTGGCTGCTTTTATCCATGCGCAAGATTTCAAGTTTAAATCTTTCATGGCAGCTTACAAGTTCTATAATCAATATGC
ACTAAAGACCAATGATGGCGAATACTATCTAGAAGGCATGGAGGAGCGTGTTCTCTTTAACGCCCTCTACTTTGCCAATG
GAGATGAAGCGATCGCTAAGGATATTGCCAATGAAATCATCCACCAACGCTATCAACCAGCTACACCAAGCTTCCTTAAT
GCAGGTCGAGCTCGTCGCGGTGAATTGGTATCTTGCTTCCTCATCCAAGTAACAGATGATATGAACTCAATCGGTCGCTC
TATCAACTCTGCCCTTCAACTATCTCGTATCGGAGGCGGAGTCGGTATTTCCCTCAGCAATCTGCGGGAAGCTGGAGCAC
CTATCAAGGGTTATGAAGGAGCTGCGTCTGGCGTTGTGCCTGTTATGAAACTCTTTGAAGACAGCTTCTCCTACTCTAAC
CAGCTGGGACAACGTCAGGGAGCTGGAGTTGTTTACCTCAACGTCTTCCACCCAGATATCATCGCTTTCCTTTCAACTAA
GAAAGAAAATGCTGACGAAAAAGTTCGGGTTAAAACCCTCTCACTCGGTGTTGTCATTCCAGATAAATTCTACGAATTAG
CTCGTAAAAATGAAGAAATGTATCTCTTCAGCCCATATTCTGTTGAACGCGAGTACGGAGTGCCATTTGCCTACCTTGAC
ATCACTGAAAAATATGATGAATTGGTCGCTAATCCAAATATCACTAAAACCAAGATCAAGGCTCGTGATTTGGAAACAGA
AATTTCTAAACTCCAACAAGAATCTGGCTATCCTTATGTCGTAAACATCGATACAGCTAATCGTTCAAATCCAATTGACG
GTAAAATCATCATGAGTAACCTTTGCTCTGAAATCCTGCAAGTGCAAGAACCTAGTCTTTTGAATGATGCACAAGAGTAT
CTTCACTTGGGAACAGATGTATCATGTAACTTAGGTTCTACCAACGTTGTGAACATGATGACTTCTCCTGACTTTGGAAA
ATCCATCCGAACTATGACTCGCGCTCTTACTTTCGTGACTGATAGTTCACACATCACAGCTGTACCTTCTATTGATCACG
GAAATAGCCTAGCTCATACTTTTGGTTTAGGTGCTATGGGACTACACAGTTATTTAGCTCAGCAGTTGATCGATTACGGA
TCAGCGGAAGCTGTAGAGTTCACCAGCATCTACTTCATGCTCATGAACTACTGGACTTTGGTTGAGTCTAATAATATCGC
TCGCGAGCGTGGCGTGACCTTCCATAACTTTGAAAAATCTGACTATGCTAGCGGAACTTACTTTGACAAGTACCTGACAG
GTGAATTTGTACCTAAGTCCGACCGTGTCAAAGAACTCTTCGCGGGAATCTTTATCCCGTCTGCAGAGGATTGGGCTGAG
TTGCGTGACAAGGTAAAAGCGGACGGTCTCTATCACCAAAACCGCCTAGCTGTTGCACCAAATGGCTCTATCAGCTACAT
CAACGATGTTTCTGCTTCAATCCATCCAATTACTCAACGGATCGAAGAACGTCAAGAAAAGAAAATTGGTAAGATCTACT
ATCCTGCTGCTGGTCTGTCAACTGAGACTATCCCTTACTACACCAGCGCTTATGACATGGACATGCGCAAGGTTATTGAT
GTCTATGCAGCCGCAACTGAGCATGTGGACCAAGGACTTTCCCTGACTCTCTTTATGCGCAGCGATATTCCTAAAGGTCT
CTACGAGTGGAAAAAAGAAAGCAAGCAAACAACTCGTGATCTTTCTATCCTGCGTAACTACGCCTTCAACAAGGGTATCA
AGTCCATCTACTACGTCCGCACCTTCACTGACGATGGTGGCGAAGTAGGTGCCAACCAATGTGAAAGCTGTGTGATATAG

Protein sequence :
MGLKHLEDVTYFRLNNEINRPVNGQIMLHKDQEALEAFFKENVEPNTKQFSSITEKIKYLIEENYLEKEFIQLYSPEYIE
ELAAFIHAQDFKFKSFMAAYKFYNQYALKTNDGEYYLEGMEERVLFNALYFANGDEAIAKDIANEIIHQRYQPATPSFLN
AGRARRGELVSCFLIQVTDDMNSIGRSINSALQLSRIGGGVGISLSNLREAGAPIKGYEGAASGVVPVMKLFEDSFSYSN
QLGQRQGAGVVYLNVFHPDIIAFLSTKKENADEKVRVKTLSLGVVIPDKFYELARKNEEMYLFSPYSVEREYGVPFAYLD
ITEKYDELVANPNITKTKIKARDLETEISKLQQESGYPYVVNIDTANRSNPIDGKIIMSNLCSEILQVQEPSLLNDAQEY
LHLGTDVSCNLGSTNVVNMMTSPDFGKSIRTMTRALTFVTDSSHITAVPSIDHGNSLAHTFGLGAMGLHSYLAQQLIDYG
SAEAVEFTSIYFMLMNYWTLVESNNIARERGVTFHNFEKSDYASGTYFDKYLTGEFVPKSDRVKELFAGIFIPSAEDWAE
LRDKVKADGLYHQNRLAVAPNGSISYINDVSASIHPITQRIEERQEKKIGKIYYPAAGLSTETIPYYTSAYDMDMRKVID
VYAAATEHVDQGLSLTLFMRSDIPKGLYEWKKESKQTTRDLSILRNYAFNKGIKSIYYVRTFTDDGGEVGANQCESCVI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 5e-180 54